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Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

图像与视频处理 · 电气工程与系统科学 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Histopathology slide digitization introduces scanner-induced domain shift that can significantly impact computational pathology models based on deep learning methods. In the state-of-the-art, this shift is often characterized at a broad…

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

图像与视频处理 · 电气工程与系统科学 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

This paper presents a novel approach for unsupervised domain adaptation (UDA) targeting H&E stained histology images. Existing adversarial domain adaptation methods may not effectively align different domains of multimodal distributions…

计算机视觉与模式识别 · 计算机科学 2023-10-02 Ravi Kant Gupta , Shounak Das , Amit Sethi

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

计算机视觉与模式识别 · 计算机科学 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

图像与视频处理 · 电气工程与系统科学 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Designing a deep neural network (DNN) with good generalization capability is a complex process especially when the weights are severely quantized. Model averaging is a promising approach for achieving the good generalization capability of…

机器学习 · 计算机科学 2020-02-04 Sungho Shin , Yoonho Boo , Wonyong Sung

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

图像与视频处理 · 电气工程与系统科学 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Domain generalization in computational histopathology is hindered by heterogeneity in whole slide images (WSIs), caused by variations in tissue preparation, staining, and imaging conditions across institutions. Unlike machine learning…

计算机视觉与模式识别 · 计算机科学 2025-09-03 Hikmat Khan , Syed Farhan Alam Zaidi , Pir Masoom Shah , Kiruthika Balakrishnan , Rabia Khan , Muhammad Waqas , Jia Wu

Developing nations lack adequate number of hospitals with modern equipment and skilled doctors. Hence, a significant proportion of these nations' population, particularly in rural areas, is not able to avail specialized and timely…

计算机视觉与模式识别 · 计算机科学 2020-03-20 Shubham Goswami , Suril Mehta , Dhruva Sahrawat , Anubha Gupta , Ritu Gupta

The Gleason grading system using histological images is the most powerful diagnostic and prognostic predictor of prostate cancer. The current standard inspection is evaluating Gleason H&E-stained histopathology images by pathologists.…

图像与视频处理 · 电气工程与系统科学 2020-12-10 Haotian Xie , Yong Zhang , Jun Wang , Jingjing Zhang , Yifan Ma , Zhaogang Yang

Face anti-spoofing approaches based on domain generalization (DG) have drawn growing attention due to their robustness for unseen scenarios. Previous methods treat each sample from multiple domains indiscriminately during the training…

计算机视觉与模式识别 · 计算机科学 2021-07-01 Shubao Liu , Ke-Yue Zhang , Taiping Yao , Kekai Sheng , Shouhong Ding , Ying Tai , Jilin Li , Yuan Xie , Lizhuang Ma

Image segmentation is pivotal in medical image analysis, facilitating clinical diagnosis, treatment planning, and disease evaluation. Deep learning has significantly advanced automatic segmentation methodologies by providing superior…

图像与视频处理 · 电气工程与系统科学 2026-01-22 Zhengyong Huang , Ning Jiang , Xingwen Sun , Lihua Zhang , Peng Chen , Jens Domke , Yao Sui

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Hao Guan , Mingxia Liu

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Lesion detection is a fundamental problem in the computer-aided diagnosis scheme for mammography. The advance of deep learning techniques have made a remarkable progress for this task, provided that the training data are large and…

图像与视频处理 · 电气工程与系统科学 2021-11-23 Zheren Li , Zhiming Cui , Sheng Wang , Yuji Qi , Xi Ouyang , Qitian Chen , Yuezhi Yang , Zhong Xue , Dinggang Shen , Jie-Zhi Cheng

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

计算机视觉与模式识别 · 计算机科学 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

Deep learning (DL) models are being deployed at medical centers to aid radiologists for diagnosis of lung conditions from chest radiographs. Such models are often trained on a large volume of publicly available labeled radiographs. These…

计算机视觉与模式识别 · 计算机科学 2020-12-22 Abhishek K Dubey , Michael T Young , Christopher Stanley , Dalton Lunga , Jacob Hinkle

Accurate segmentation of the prostate from magnetic resonance (MR) images provides useful information for prostate cancer diagnosis and treatment. However, automated prostate segmentation from 3D MR images still faces several challenges.…

计算机视觉与模式识别 · 计算机科学 2019-08-16 Qikui Zhu , Bo Du , Pingkun Yan