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There has been substantial interest in developing Markov chain Monte Carlo algorithms based on piecewise-deterministic Markov processes. However existing algorithms can only be used if the target distribution of interest is differentiable…

统计理论 · 数学 2021-11-12 Augustin Chevallier , Sam Power , Andi Q. Wang , Paul Fearnhead

The objective is to model longitudinal and survival data jointly taking into account the dependence between the two responses in a real HIV/AIDS dataset using a shared parameter approach inside a Bayesian framework. We propose a linear…

应用统计 · 统计学 2016-05-02 Rui Martins

Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing…

统计方法学 · 统计学 2017-10-24 Meike Köhler , Nikolaus Umlauf , Sonja Greven

Bayes linear kinematics and Bayes linear Bayes graphical models provide an extension of Bayes linear methods so that full conditional updates may be combined with Bayes linear belief adjustment. In this paper we investigate the application…

统计方法学 · 统计学 2016-11-16 Kevin J. Wilson , Malcolm Farrow

This paper introduces a versatile approach for computing the risk of collision specifically tailored for scenarios featuring low relative encounter velocities, but with potential applicability across a wide range of situations. The…

Discrete-time hazard models are widely used when event times are measured in intervals or are not precisely observed. While these models can be estimated using standard generalized linear model techniques, they rely on extensive data…

统计方法学 · 统计学 2025-07-14 Benjamin Müller , Nikolaus Umlauf , Johannes Seiler , Kenneth Harttgen , Stefan Lang

Aiming for accurate estimation of system reliability of load-sharing systems, a flexible model for such systems is constructed by approximating the cumulative hazard functions of component lifetimes using piecewise linear functions. The…

统计方法学 · 统计学 2023-01-05 Shilpi Biswas , Ayon Ganguly , Debanjan Mitra

Health policy decisions are often informed by estimates of long-term survival based primarily on short-term data. A range of methods are available to include longer-term information, but there has previously been no comprehensive and…

统计方法学 · 统计学 2025-05-05 Christopher Jackson

Continuous-time multi-state survival models can be used to describe health-related processes over time. In the presence of interval-censored times for transitions between the living states, the likelihood is constructed using transition…

统计方法学 · 统计学 2017-03-24 Robson J. M. Machado , Ardo van den Hout

In many applications of survival data analysis, the individuals are treated in different medical centres or belong to different clusters defined by geographical or administrative regions. The analysis of such data requires accounting for…

统计方法学 · 统计学 2022-05-03 Rubio , F. J. , Drikvandi , R

The proportional hazards model represents the most commonly assumed hazard structure when analysing time to event data using regression models. We study a general hazard structure which contains, as particular cases, proportional hazards,…

统计方法学 · 统计学 2018-05-24 Francisco J. Rubio , Laurent Remontet , Nicholas P. Jewell , Aurélien Belot

In recent years, mixture cure models have gained increasing popularity in survival analysis as an alternative to the Cox proportional hazards model, particularly in settings where a subset of patients is considered cured. The proportional…

统计方法学 · 统计学 2025-12-10 Fatih Kızılaslan , Valeria Vitelli

It is standard practice for covariates to enter a parametric model through a single distributional parameter of interest, for example, the scale parameter in many standard survival models. Indeed, the well-known proportional hazards model…

统计方法学 · 统计学 2020-08-10 Kevin Burke , Gilbert MacKenzie

In applied time-to-event analysis, a flexible parametric approach is to model the hazard rate as a piecewise constant function of time. However, the change points and values of the piecewise constant hazard are usually unknown and need to…

统计方法学 · 统计学 2024-08-08 Manuel Rosenbaum , Jan Beyersmann , Michael Vogt

Particle Markov Chain Monte Carlo methods are used to carry out inference in non-linear and non-Gaussian state space models, where the posterior density of the states is approximated using particles. Current approaches usually perform…

统计计算 · 统计学 2019-09-30 Eduardo F. Mendes , Christopher K. Carter , David Gunawan , Robert Kohn

There is increasing interest in flexible parametric models for the analysis of time-to-event data, yet Bayesian approaches that offer incorporation of prior knowledge remain underused. A flexible Bayesian parametric model has recently been…

Survival models incorporating random effects to account for unmeasured heterogeneity are being increasingly used in biostatistical and applied research. Specifically, unmeasured covariates whose lack of inclusion in the model would lead to…

统计方法学 · 统计学 2020-05-06 Alessandro Gasparini , Mark S. Clements , Keith R. Abrams , Michael J. Crowther

Characterization of long-term disease dynamics, from disease-free to end-stage, is integral to understanding the course of neurodegenerative diseases such as Parkinson's and Alzheimer's; and ultimately, how best to intervene. Natural…

应用统计 · 统计学 2018-01-12 Dan Li , Samuel Iddi , Wesley K. Thompson , Michael C. Donohue

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Hamiltonian Monte Carlo (HMC) is an efficient and effective means of sampling posterior distributions on Euclidean space, which has been extended to manifolds with boundary. However, some applications require an extension to more general…

种群与进化 · 定量生物学 2017-06-26 Vu Dinh , Arman Bilge , Cheng Zhang , Frederick A. Matsen