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The cytoskeleton (CSK) plays an important role in many cell functions. Given the similarities between the mechanical behavior of tensegrity structures and the CSK, many studies have proposed different tensegrity-based models for simulating…

应用物理 · 物理学 2025-10-03 Ziran Zhou , Jacinto Ulloa , Guruswami Ravichandran , Jose E. Andrade

Imitation learning practitioners have often noted that conditioning policies on previous actions leads to a dramatic divergence between "held out" error and performance of the learner in situ. Interactive approaches can provably address…

机器学习 · 计算机科学 2021-02-12 Jonathan Spencer , Sanjiban Choudhury , Arun Venkatraman , Brian Ziebart , J. Andrew Bagnell

Cross-modal representation learning learns a shared embedding between two or more modalities to improve performance in a given task compared to using only one of the modalities. Cross-modal representation learning from different data types…

机器学习 · 计算机科学 2023-09-12 Felix Ott , David Rügamer , Lucas Heublein , Bernd Bischl , Christopher Mutschler

Neural network-based models augmented with unsupervised pre-trained knowledge have achieved impressive performance on text summarization. However, most existing evaluation methods are limited to an in-domain setting, where summarizers are…

计算与语言 · 计算机科学 2020-10-23 Yiran Chen , Pengfei Liu , Ming Zhong , Zi-Yi Dou , Danqing Wang , Xipeng Qiu , Xuanjing Huang

Accurate cell counting is essential in various biomedical research and clinical applications, including cancer diagnosis, stem cell research, and immunology. Manual counting is labor-intensive and error-prone, motivating automation through…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Abdurahman Ali Mohammed , Catherine Fonder , Ying Wei , Wallapak Tavanapong , Donald S Sakaguchi , Qi Li , Surya K. Mallapragada

Continual learning aims to learn multiple tasks sequentially while preserving prior knowledge, but faces the challenge of catastrophic forgetting when adapting to new tasks. Recently, approaches leveraging pre-trained models have gained…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Quan Cheng , Yuanyu Wan , Lingyu Wu , Chenping Hou , Lijun Zhang

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

计算机视觉与模式识别 · 计算机科学 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

Accurate single-cell analysis is critical for diagnostics, immunomonitoring, and cell therapy, but coincident events - where multiple cells overlap in a sensing zone - can severely compromise signal fidelity. We present a hybrid framework…

信号处理 · 电气工程与系统科学 2025-07-18 Moritz Leuthner , Rafael Vorländer , Oliver Hayden

Single-cell representation learning (SCRL) from gene expression data offers a way to uncover the complex regulatory logic underlying cellular function. Inspired by large language models in natural language modeling, several single-cell…

机器学习 · 计算机科学 2026-05-11 Sachini Weerasekara , Natasha Darras , Sagar Kamarthi , Colles Price , Jacqueline Isaacs

Cell line authentication plays a crucial role in the biomedical field, ensuring researchers work with accurately identified cells. Supervised deep learning has made remarkable strides in cell line identification by studying cell…

计算机视觉与模式识别 · 计算机科学 2023-06-30 Lei Tong , Adam Corrigan , Navin Rathna Kumar , Kerry Hallbrook , Jonathan Orme , Yinhai Wang , Huiyu Zhou

Semi-supervised medical image segmentation has attracted much attention in recent years because of the high cost of medical image annotations. In this paper, we propose a novel Inherent Consistent Learning (ICL) method, aims to learn robust…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Ye Zhu , Jie Yang , Si-Qi Liu , Ruimao Zhang

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Recent transformer-based approaches demonstrate promising results on relational scientific information extraction. Existing datasets focus on high-level description of how research is carried out. Instead we focus on the subtleties of how…

计算与语言 · 计算机科学 2021-09-23 Ian H. Magnusson , Scott E. Friedman

Representational Similarity Analysis is a method from cognitive neuroscience, which helps in comparing representations from two different sources of data. In this paper, we propose using Representational Similarity Analysis to probe the…

计算与语言 · 计算机科学 2022-07-19 Shounak Naik , Rajaswa Patil , Swati Agarwal , Veeky Baths

Cardinality estimation (CE), the task of predicting the result size of queries is a critical component of query optimization. Accurate estimates are essential for generating efficient query execution plans. Recently, machine learning…

数据库 · 计算机科学 2025-12-16 Lankadinee Rathuwadu , Guanli Liu , Christopher Leckie , Renata Borovica-Gajic

Generalization methods offer a powerful solution to one of the key drawbacks of randomized controlled trials (RCTs): their limited representativeness. By enabling the transport of treatment effect estimates to target populations subject to…

统计方法学 · 统计学 2025-05-20 Ahmed Boughdiri , Clément Berenfeld , Julie Josse , Erwan Scornet

We describe a simple automated method to extract and quantify transient heterogeneous dynamical changes from large datasets generated in single molecule/particle tracking experiments. Based on wavelet transform, the method transforms raw…

数据分析、统计与概率 · 物理学 2013-06-04 Kejia Chen , Bo Wang , Juan Guan , Steve Granick

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

计算机视觉与模式识别 · 计算机科学 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Cell identity encompasses various semantic aspects of a cell, including cell type, pathway information, disease information, and more, which are essential for biologists to gain insights into its biological characteristics. Understanding…

基因组学 · 定量生物学 2024-06-12 Suyuan Zhao , Jiahuan Zhang , Yushuai Wu , Yizhen Luo , Zaiqing Nie

By supporting multi-modal retrieval training and evaluation, image captioning datasets have spurred remarkable progress on representation learning. Unfortunately, datasets have limited cross-modal associations: images are not paired with…

计算与语言 · 计算机科学 2021-03-25 Zarana Parekh , Jason Baldridge , Daniel Cer , Austin Waters , Yinfei Yang