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Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

医学物理 · 物理学 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

Purpose: To evaluate reliability of upright CT for proton dose calculation and feasibility of a simplified phantom configuration for accelerated routine QA. Methods: A calibration phantom was scanned on an upright CT following consensus…

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

医学物理 · 物理学 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Accurately translating medical images between different modalities, such as Computed Tomography (CT) to Magnetic Resonance Imaging (MRI), has numerous downstream clinical and machine learning applications. While several methods have been…

图像与视频处理 · 电气工程与系统科学 2025-12-03 Yuwen Chen , Nicholas Konz , Hanxue Gu , Haoyu Dong , Yaqian Chen , Lin Li , Jisoo Lee , Maciej A. Mazurowski

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Purpose: To characterize image quality, imaging dose, and dose calculation accuracy for an upright CT scanner with a six-degree-of-freedom patient positioning system. Methods: Imaging dose (CTDIvol) was measured at 120 kVp and 200 mAs.…

Background: In MR-guided proton therapy planning, aligning MR and CT images is key for MR-based CT synthesis, especially in mobile regions like the head-and-neck. Misalignments here can lead to less accurate synthetic CT (sCT) images,…

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

In medical image segmentation, particularly in UNet-like architectures, upsampling is primarily used to transform smaller feature maps into larger ones, enabling feature fusion between encoder and decoder features and supporting multi-scale…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Chengkun Sun , Jinqian Pan , Renjie Liang , Zhengkang Fan , Xin Miao , Jiang Bian , Jie Xu

Image registration is an essential technique for the analysis of Computed Tomography (CT) images in clinical practice. However, existing methodologies are predominantly tailored to a specific organ of interest and often exhibit lower…

计算机视觉与模式识别 · 计算机科学 2025-03-31 Xuan Loc Pham , Mathias Prokop , Bram van Ginneken , Alessa Hering

Deformable image registration, estimating the spatial transformation between different images, is an important task in medical imaging. Many previous studies have used learning-based methods for multi-stage registration to perform 3D image…

计算机视觉与模式识别 · 计算机科学 2024-07-23 Jian-Qing Zheng , Ziyang Wang , Baoru Huang , Ngee Han Lim , Tonia Vincent , Bartlomiej W. Papiez

Delineation of tumors and organs-at-risk permits detecting and correcting changes in the patients' anatomy throughout the treatment, making it a core step of adaptive proton therapy (APT). Although AI-based auto-contouring technologies have…

Image-guided adaptive lung radiotherapy requires accurate tumor and organs segmentation from during treatment cone-beam CT (CBCT) images. Thoracic CBCTs are hard to segment because of low soft-tissue contrast, imaging artifacts, respiratory…

图像与视频处理 · 电气工程与系统科学 2022-03-01 Jue Jiang , Harini Veeraraghavan

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

医学物理 · 物理学 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…

医学物理 · 物理学 2025-08-22 Erik Engwall , Victor Mikhalev , Johan Sundström , Otte Marthin , Viktor Wase

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Precise patient positioning and thus precise positioning of the planning target volume (PTV) is a prerequisite for effective treatment in percutaneous radiation therapy. Conventional imaging modalities used to ensure exact positioning for…

医学物理 · 物理学 2016-02-12 Manfred Wiencierz , Kathrin Kruppa , Lutz Lüdemann

The treatment of degenerative spinal disorders requires an understanding of the individual spinal anatomy and curvature in 3D. An upright spinal pose (i.e. standing) under natural weight bearing is crucial for such bio-mechanical analysis.…

图像与视频处理 · 电气工程与系统科学 2021-01-14 Amirhossein Bayat , Anjany Sekuboyina , Johannes C. Paetzold , Christian Payer , Darko Stern , Martin Urschler , Jan S. Kirschke , Bjoern H. Menze

Image registration is a fundamental technique in the analysis of longitudinal and multi-phase CT images within clinical practice. However, most existing methods are tailored for single-organ applications, limiting their generalizability to…

A hybrid imaging system consisting of a standard CT scanner and a low-profile photon-counting detector insert in contact with the patient's body has been used to produce ultrahigh-resolution images in a limited volume in chest scans of…

医学物理 · 物理学 2022-09-05 Dakota H. King , Eric E. Bennett , Dumitru Mazilu , Muyang Wang , Marcus Y. Chen , Han Wen
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