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In clinical practice, single-radiotracer positron emission tomography (PET) is commonly used for imaging. Although multi-tracer PET imaging can provide supplementary information of radiotracers that are sensitive to physiological function…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Bin Huang , Feihong Xu , Xinchong Shi , Shan Huang , Binxuan Li , Fei Li , Qiegen Liu

Probabilistic time series forecasting is crucial in many application domains such as retail, ecommerce, finance, or biology. With the increasing availability of large volumes of data, a number of neural architectures have been proposed for…

机器学习 · 计算机科学 2021-12-15 Olivier Sprangers , Sebastian Schelter , Maarten de Rijke

Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their…

图像与视频处理 · 电气工程与系统科学 2025-04-17 Kangbo Ma

The increasing need to simulate the dynamics of photoexcited molecular and nanosystems in the sub-picosecond regime demands new efficient tools able to describe the quantum nature of matter at a low computational cost. By combining the…

Recent advances in molecular machine learning, especially deep neural networks such as Graph Neural Networks (GNNs) for predicting structure activity relationships (SAR) have shown tremendous potential in computer-aided drug discovery.…

机器学习 · 计算机科学 2022-03-14 Vishal Dey , Raghu Machiraju , Xia Ning

To obtain high-quality positron emission tomography (PET) scans while reducing radiation exposure to the human body, various approaches have been proposed to reconstruct standard-dose PET (SPET) images from low-dose PET (LPET) images. One…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Zeyu Han , Yuhan Wang , Luping Zhou , Peng Wang , Binyu Yan , Jiliu Zhou , Yan Wang , Dinggang Shen

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

计算机视觉与模式识别 · 计算机科学 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

Recent neuroimaging studies have highlighted the importance of network-centric brain analysis, particularly with functional magnetic resonance imaging. The emergence of Deep Neural Networks has fostered a substantial interest in predicting…

神经元与认知 · 定量生物学 2023-09-06 Xuan Kan , Antonio Aodong Chen Gu , Hejie Cui , Ying Guo , Carl Yang

Adapting neural networks to new tasks typically requires task-specific fine-tuning, which is time-consuming and reliant on labeled data. We explore a generative alternative that produces task-specific parameters directly from task identity,…

机器学习 · 计算机科学 2025-06-24 Lijun Zhang , Xiao Liu , Hui Guan

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

神经元与认知 · 定量生物学 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens

Positron emission tomography (PET) is a key nuclear medicine imaging modality that visualizes radiotracer distributions to quantify in vivo physiological and metabolic processes, playing an irreplaceable role in disease management. Despite…

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Bin Huang , Xubiao Liu , Lei Fang , Qiegen Liu , Bingxuan Li

Drug-target interaction (DTI) prediction is a challenging, albeit essential task in drug repurposing. Learning on graph models have drawn special attention as they can significantly reduce drug repurposing costs and time commitment.…

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

机器学习 · 计算机科学 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Data-driven medical AI is traditionally formulated as a discriminative mapping from input $X$ to output $Y$ via a learned function $f$, which does not generalize well across heterogeneous data and modalities encountered in real-world…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Hantao Zhang , Weidong Guo , Yuhe Liu , Jiancheng Yang , Sathvik Bhagavan , Danli Shi , Mingda Xu , Pascal Fua

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Forecasting the progression of neurodegenerative diseases, such as Parkinson's disease, is essential for effective long-term planning and personalized therapeutic intervention. Existing systems typically produce scalar clinical scores that…

机器学习 · 计算机科学 2026-05-29 Danylo Boiko , Viktoriia Mishkurova

This study explores the applicability of a graph-based interaction-aware trajectory prediction model, originally developed for the transportation domain, to forecast particle trajectories in three-dimensional discrete element simulations.…

计算物理 · 物理学 2025-03-07 Abhishek Setty , Lukas Morand , Poojitha Ramachandra , Claas Bierwisch

The accurate diagnosis and segmentation of tumors in contrast-enhanced Computed Tomography (CT) are fundamentally driven by the distinctive hemodynamic profiles of contrast agents over time. However, in real-world clinical practice,…

计算机视觉与模式识别 · 计算机科学 2026-03-02 Zishuo Wan , Qinqin Kang , Na Li , Yi Huang , Qianru Zhang , Le Lu , Yun Bian , Dawei Ding , Ke Yan

Diffusion Probabilistic Models (DPMs) have achieved great success in image generation but suffer from high inference latency due to their iterative denoising nature. Motivated by the evolving feature dynamics across the denoising…

计算机视觉与模式识别 · 计算机科学 2026-03-23 Haodong He , Yuan Gao , Weizhong Zhang , Gui-Song Xia