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This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

计算与语言 · 计算机科学 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

计算与语言 · 计算机科学 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Medical question answering requires extensive access to specialized conceptual knowledge. The current paradigm, Retrieval-Augmented Generation (RAG), acquires expertise medical knowledge through large-scale corpus retrieval and uses this…

计算与语言 · 计算机科学 2025-02-20 Sichu Liang , Linhai Zhang , Hongyu Zhu , Wenwen Wang , Yulan He , Deyu Zhou

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

信息检索 · 计算机科学 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

Retrieval-augmented generation (RAG) improves large language model reliability by grounding generated responses in external evidence. However, RAG performance depends on the relevance of retrieved passages, the quality of evidence ranking,…

信息检索 · 计算机科学 2026-05-05 Fariba Afrin Irany , Sampson Akwafuo

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Retrieval-augmented generation (RAG) effectively addresses issues of static knowledge and hallucination in large language models. Existing studies mostly focus on question scenarios with clear user intents and concise answers. However, it…

计算与语言 · 计算机科学 2025-02-18 Shuting Wang , Xin Yu , Mang Wang , Weipeng Chen , Yutao Zhu , Zhicheng Dou

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

计算与语言 · 计算机科学 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Medical question answering (QA) requires extensive access to domain-specific knowledge. A promising direction is to enhance large language models (LLMs) with external knowledge retrieved from medical corpora or parametric knowledge stored…

计算与语言 · 计算机科学 2025-10-22 Lei Li , Xiao Zhou , Yingying Zhang , Xian Wu

Language models (LMs) are known to suffer from hallucinations and misinformation. Retrieval augmented generation (RAG) that retrieves verifiable information from an external knowledge corpus to complement the parametric knowledge in LMs…

计算与语言 · 计算机科学 2024-10-14 Zhuohang Li , Jiaxin Zhang , Chao Yan , Kamalika Das , Sricharan Kumar , Murat Kantarcioglu , Bradley A. Malin

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

计算与语言 · 计算机科学 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

The rapid growth of medical knowledge and increasing complexity of clinical practice pose challenges. In this context, large language models (LLMs) have demonstrated value; however, inherent limitations remain. Retrieval-augmented…

Automated question-answering (QA) systems increasingly rely on retrieval-augmented generation (RAG) to ground large language models (LLMs) in authoritative medical knowledge, ensuring clinical accuracy and patient safety in Artificial…

计算与语言 · 计算机科学 2026-03-05 Aswini Sivakumar , Vijayan Sugumaran , Yao Qiang

Retrieval-augmented generation (RAG) improves large language models (LLMs) by using external knowledge to guide response generation, reducing hallucinations. However, RAG, particularly multi-modal RAG, can introduce new hallucination…

机器学习 · 计算机科学 2025-01-08 Matin Mortaheb , Mohammad A. Amir Khojastepour , Srimat T. Chakradhar , Sennur Ulukus

The emergent abilities of large language models (LLMs) have demonstrated great potential in solving medical questions. They can possess considerable medical knowledge, but may still hallucinate and are inflexible in the knowledge updates.…

计算与语言 · 计算机科学 2024-10-14 Guangzhi Xiong , Qiao Jin , Xiao Wang , Minjia Zhang , Zhiyong Lu , Aidong Zhang

In high-stakes information domains such as healthcare, where large language models (LLMs) can produce hallucinations or misinformation, retrieval-augmented generation (RAG) has been proposed as a mitigation strategy, grounding model outputs…

信息检索 · 计算机科学 2026-04-07 Saeedeh Javadi , Sara Mirabi , Manan Gangar , Bahadorreza Ofoghi

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

计算与语言 · 计算机科学 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Retrieval-Augmented Generation (RAG) aims to reduce hallucination by grounding answers in retrieved evidence, yet hallucinated answers remain common even when relevant documents are available. Existing evaluations focus on answer-level or…

计算与语言 · 计算机科学 2026-05-21 Passant Elchafei , Monorama Swain , Shahed Masoudian , Markus Schedl
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