中文
相关论文

相关论文: Synthetic Data from Diffusion Models Improve Drug …

200 篇论文

Artificial intelligence (AI) is increasingly used in every stage of drug development. One challenge facing drug discovery AI is that drug pharmacokinetic (PK) datasets are often collected independently from each other, often with limited…

定量方法 · 定量生物学 2025-07-03 Bing Hu , Anita Layton , Helen Chen

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

The role of Artificial Intelligence (AI) is growing in every stage of drug development. Nevertheless, a major challenge in drug discovery AI remains: Drug pharmacokinetic (PK) and Drug-Target Interaction (DTI) datasets collected in…

定量方法 · 定量生物学 2025-10-27 Bing Hu , Jong-Hoon Park , Helen Chen , Young-Rae Cho , Anita Layton

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

计算机视觉与模式识别 · 计算机科学 2024-10-04 Lakshmi Nair

The rapid advancement of generative models, such as Stable Diffusion, raises a key question: how can synthetic data from these models enhance predictive modeling? While they can generate vast amounts of datasets, only a subset meaningfully…

机器学习 · 统计学 2025-05-09 Jialong Jiang , Wenkang Hu , Jian Huang , Yuling Jiao , Xu Liu

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

图像与视频处理 · 电气工程与系统科学 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Recent years have witnessed a surge in the popularity of Machine Learning (ML), applied across diverse domains. However, progress is impeded by the scarcity of training data due to expensive acquisition and privacy legislation. Synthetic…

机器学习 · 计算机科学 2024-02-05 André Bauer , Simon Trapp , Michael Stenger , Robert Leppich , Samuel Kounev , Mark Leznik , Kyle Chard , Ian Foster

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

机器学习 · 计算机科学 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

The increasing reliance on large-scale datasets in machine learning poses significant privacy and ethical challenges, particularly in sensitive domains such as face recognition. Synthetic data generation offers a promising alternative;…

计算机视觉与模式识别 · 计算机科学 2025-10-27 Parsa Rahimi , Damien Teney , Sebastien Marcel

The emergence of generative AI models has dramatically expanded the availability and use of synthetic data across scientific, industrial, and policy domains. While these developments open new possibilities for data analysis, they also raise…

机器学习 · 统计学 2026-03-06 Ahmad Abdel-Azim , Ruoyu Wang , Xihong Lin

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

机器学习 · 计算机科学 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Federated semi-supervised learning (FSSL) is primarily challenged by two factors: the scarcity of labeled data across clients and the non-independent and identically distribution (non-IID) nature of data among clients. In this paper, we…

机器学习 · 计算机科学 2025-01-07 Zhongwei Wang , Tong Wu , Zhiyong Chen , Liang Qian , Yin Xu , Meixia Tao

Generative models such as Large Language Models, Diffusion Models, and generative adversarial networks have recently revolutionized the creation of synthetic data, offering scalable solutions to data scarcity, privacy, and annotation…

机器学习 · 计算机科学 2025-08-28 Dawei Li , Yue Huang , Ming Li , Tianyi Zhou , Xiangliang Zhang , Huan Liu

The artificial intelligence (AI) world is running out of real data for training increasingly large generative models, resulting in accelerating pressure to train on synthetic data. Unfortunately, training new generative models with…

机器学习 · 计算机科学 2024-08-30 Sina Alemohammad , Ahmed Imtiaz Humayun , Shruti Agarwal , John Collomosse , Richard Baraniuk

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

医学物理 · 物理学 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

The scarcity of accessible, compliant, and ethically sourced data presents a considerable challenge to the adoption of artificial intelligence (AI) in sensitive fields like healthcare, finance, and biomedical research. Furthermore, access…

机器学习 · 计算机科学 2025-04-02 Kumar Kshitij Patel , Weitong Zhang , Lingxiao Wang

Drug discovery is a complex, resource-intensive process requiring significant time and cost to bring new medicines to patients. Many generative models aim to accelerate drug discovery, but few produce synthetically accessible molecules.…

机器学习 · 计算机科学 2025-01-30 Zygimantas Jocys , Zhanxing Zhu , Henriette M. G. Willems , Katayoun Farrahi
‹ 上一页 1 2 3 10 下一页 ›