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Intensive Care Units (ICUs) provide critical care and life support for most severely ill and injured patients in the hospital. With the need for ICUs growing rapidly and unprecedentedly, especially during COVID-19, accurately identifying…

人工智能 · 计算机科学 2024-12-04 Weihan Xu

Determining whether hypotensive patients in intensive care units (ICUs) should receive fluid bolus therapy (FBT) has been an extremely challenging task for intensive care physicians as the corresponding increase in blood pressure has been…

机器学习 · 计算机科学 2018-12-04 Uma M. Girkar , Ryo Uchimido , Li-wei H. Lehman , Peter Szolovits , Leo Celi , Wei-Hung Weng

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

定量方法 · 定量生物学 2019-10-24 Pejman F. Ghalati , Satya S. Samal , Jayesh S. Bhat , Robert Deisz , Gernot Marx , Andreas Schuppert

Sepsis accounts for nearly 20% of global ICU admissions, yet conventional prediction models often fail to effectively integrate heterogeneous data streams, remaining either siloed by modality or reliant on brittle early fusion. In this…

机器学习 · 计算机科学 2025-12-18 Ryan Cartularo

We develop a deep learning approach to predicting a set of ventilator parameters for a mechanically ventilated septic patient using a long and short term memory (LSTM) recurrent neural network (RNN) model. We focus on short-term predictions…

定量方法 · 定量生物学 2022-02-23 Zhijun Zeng , Zhen Hou , Ting Li , Lei Deng , Jianguo Hou , Xinran Huang , Jun Li , Meirou Sun , Yunhan Wang , Qiyu Wu , Wenhao Zheng , Hua Jiang , Qi Wang

Attention mechanisms have recently demonstrated impressive performance on a range of NLP tasks, and attention scores are often used as a proxy for model explainability. However, there is a debate on whether attention weights can, in fact,…

计算与语言 · 计算机科学 2022-11-16 Bingyang Wen , K. P. Subbalakshmi , Fan Yang

The early and accurate diagnosis of sepsis is critical for enhancing patient outcomes. This study aims to use heart rate variability (HRV) features to develop an effective predictive model for sepsis detection. Critical HRV features are…

机器学习 · 计算机科学 2024-08-07 Sai Balaji , Christopher Sun , Anaiy Somalwar

The recent release of large-scale healthcare datasets has greatly propelled the research of data-driven deep learning models for healthcare applications. However, due to the nature of such deep black-boxed models, concerns about…

机器学习 · 计算机科学 2021-02-16 Chuizheng Meng , Loc Trinh , Nan Xu , Yan Liu

Deep learning models are widely used nowadays for their reliability in performing various tasks. However, they do not typically provide the reasoning behind their decision, which is a significant drawback, particularly for more sensitive…

计算机视觉与模式识别 · 计算机科学 2024-12-09 Tiago Roxo , Joana C. Costa , Pedro R. M. Inácio , Hugo Proença

Sepsis is a leading cause of mortality in intensive care units and costs hospitals billions annually. Treating a septic patient is highly challenging, because individual patients respond very differently to medical interventions and there…

人工智能 · 计算机科学 2017-11-28 Aniruddh Raghu , Matthieu Komorowski , Imran Ahmed , Leo Celi , Peter Szolovits , Marzyeh Ghassemi

Predictive process monitoring aims to support the execution of a process during runtime with various predictions about the further evolution of a process instance. In the last years a plethora of deep learning architectures have been…

机器学习 · 计算机科学 2024-08-15 Martin Käppel , Lars Ackermann , Stefan Jablonski , Simon Härtl

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

机器学习 · 计算机科学 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

机器学习 · 计算机科学 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Heart disease is the number one killer, and ECGs can assist in the early diagnosis and prevention of deadly outcomes. Accurate ECG interpretation is critical in detecting heart diseases; however, they are often misinterpreted due to a lack…

机器学习 · 计算机科学 2021-10-29 Dharma KC , Chicheng Zhang , Chris Gniady , Parth Sandeep Agarwal , Sushil Sharma

Worldwide, suicide is the second leading cause of death for adolescents with past suicide attempts to be an important predictor for increased future suicides. While some people with suicidal thoughts may try to suppress them, many signal…

计算与语言 · 计算机科学 2025-11-13 Mohaiminul Islam Bhuiyan , Nur Shazwani Kamarudin , Nur Hafieza Ismail

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

机器学习 · 计算机科学 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Predicting extubation failure in intensive care is challenging due to complex data and the severe consequences of inaccurate predictions. Machine learning shows promise in improving clinical decision-making but often fails to account for…

机器学习 · 计算机科学 2024-12-03 Akram Yoosoofsah

We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…

应用统计 · 统计学 2024-03-07 Giacomo Lancia , Meri Varkila , Olaf Cremer , Cristian Spitoni

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

机器学习 · 计算机科学 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He