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Sequence labeling for extraction of medical events and their attributes from unstructured text in Electronic Health Record (EHR) notes is a key step towards semantic understanding of EHRs. It has important applications in health informatics…

计算与语言 · 计算机科学 2016-07-13 Abhyuday Jagannatha , Hong Yu

One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…

应用统计 · 统计学 2018-12-04 Luis F. Campos , Mark E. Glickman , Kristen B. Hunter

Adverse drug events (ADEs) are a serious health problem that can be life-threatening. While a lot of studies have been performed on detect correlation between a drug and an AE, limited studies have been conducted on personalized ADE risk…

机器学习 · 计算机科学 2021-04-20 Jinhe Shi , Xiangyu Gao , Chenyu Ha , Yage Wang , Guodong Gao , Yi Chen

Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a…

计算与语言 · 计算机科学 2019-05-29 Maksim Belousov , Nikola Milosevic , William Dixon , Goran Nenadic

Electronic health records (EHR) are rich heterogeneous collection of patient health information, whose broad adoption provides great opportunities for systematic health data mining. However, heterogeneous EHR data types and biased…

机器学习 · 计算机科学 2018-11-02 Yue Li , Manolis Kellis

Electronic Health Records (EHRs) contain rich, longitudinal patient information across structured (e.g., labs, vitals, and imaging) and unstructured (e.g., clinical notes) modalities. While deep learning models such as RNNs and Transformers…

机器学习 · 计算机科学 2026-02-18 Mohammad Al Olaimat , Shaika Chowdhury , Serdar Bozdag

Most existing methods for predicting drug-drug interactions (DDI) predominantly concentrate on capturing the explicit relationships among drugs, overlooking the valuable implicit correlations present between drug pairs (DPs), which leads to…

机器学习 · 计算机科学 2024-02-29 Mengying Jiang , Guizhong Liu , Yuanchao Su , Weiqiang Jin , Biao Zhao

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

机器学习 · 计算机科学 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Motivation: Unanticipated drug-drug interactions (DDIs) pose significant risks in polypharmacy, emphasizing the need for predictive methods. Recent advancements in computational techniques aim to address this challenge. Methods: We…

In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

定量方法 · 定量生物学 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Electronic Health Records (EHRs) are commonly used by the machine learning community for research on problems specifically related to health care and medicine. EHRs have the advantages that they can be easily distributed and contain many…

机器学习 · 计算机科学 2020-06-08 Kieran Chin-Cheong , Thomas Sutter , Julia E. Vogt

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

The rich longitudinal individual level data available from electronic health records (EHRs) can be used to examine treatment effect heterogeneity. However, estimating treatment effects using EHR data poses several challenges, including…

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

机器学习 · 计算机科学 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Automatic monitoring of adverse drug events (ADEs) or reactions (ADRs) is currently receiving significant attention from the biomedical community. In recent years, user-generated data on social media has become a valuable resource for this…

计算与语言 · 计算机科学 2023-11-21 Ilseyar Alimova , Elena Tutubalina

Most autonomous driving safety benchmarks use time-to-collision (TTC) to assess risk and guide safe behaviour. However, TTC-based methods treat risk as a one-dimensional closing problem, despite the inherently two-dimensional nature of…

Drug repositioning (DR) refers to identification of novel indications for the approved drugs. The requirement of huge investment of time as well as money and risk of failure in clinical trials have led to surge in interest in drug…

计算与语言 · 计算机科学 2017-05-23 Sahil Manchanda , Ashish Anand

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient…

人工智能 · 计算机科学 2022-01-19 Shuai Niu , Qing Yin , Yunya Song , Yike Guo , Xian Yang

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

Schizophrenia (SZ) is a serious mental disorder that could seriously affect the patient's quality of life. In recent years, detection of SZ based on deep learning (DL) using electroencephalogram (EEG) has received increasing attention. In…

神经元与认知 · 定量生物学 2022-07-12 Yihan Wu , Min Xia , Xiuzhu Wang , Yangsong Zhang