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Infectious disease surveillance is of great importance for the prevention of major outbreaks. Syndromic surveillance aims at developing algorithms which can detect outbreaks as early as possible by monitoring data sources which allow to…

机器学习 · 计算机科学 2021-02-01 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

定量方法 · 定量生物学 2011-10-24 Alex Skvortsov , Branko Ristic

Early Warning Signals (EWSs) are vital for implementing preventive measures before a disease turns into a pandemic. While new diseases exhibit unique behaviors, they often share fundamental characteristics from a dynamical systems…

机器学习 · 计算机科学 2025-01-15 Reza Miry , Amit K. Chakraborty , Russell Greiner , Mark A. Lewis , Hao Wang , Tianyu Guan , Pouria Ramazi

Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected…

机器学习 · 计算机科学 2021-10-19 Michael Rapp , Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

Early outbreak data analysis is critical for informing about their potential impact and interventions. However, data obtained early in outbreaks are often sensitive and subject to strict privacy restrictions. Thus, federated analysis, which…

应用统计 · 统计学 2026-01-27 Simon Busch-Moreno , Moritz U. G. Kraemer

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

统计方法学 · 统计学 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

Infectious diseases occur when pathogens from other individuals or animals infect a person, resulting in harm to both individuals and society as a whole. The outbreak of such diseases can pose a significant threat to human health. However,…

种群与进化 · 定量生物学 2024-10-24 Ghazaleh Babanejaddehaki , Aijun An , Manos Papagelis

We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…

统计方法学 · 统计学 2014-12-16 Edward S. Knock , Theodore Kypraios

This chapter surveys univariate and multivariate methods for infectious disease outbreak detection. The setting considered is a prospective one: data arrives sequentially as part of the surveillance systems maintained by public health…

统计方法学 · 统计学 2017-11-27 Benjamin Allévius , Michael Höhle

Non-pharmaceutical interventions, such as contact tracing and social distancing, are critical for controlling epidemic outbreaks, yet their dynamic interactions remain underexplored. We introduce a probabilistic framework to analyze the…

物理与社会 · 物理学 2025-12-11 Jinghui Wang , Yutian Zeng , Cong Xu , Xiyun Zhang , Zhanwei Du , Jiarong Xie , Jiu Zhang , Sen Pei , Zijian Feng , Yanqing Hu

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

定量方法 · 定量生物学 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

In the wake of the SARS-CoV-2 pandemic, there has been heightened interest from applied mathematicians in infectious disease modelling. Modelling efforts often focus on predicting whether diseases are likely to be eliminated or, instead,…

种群与进化 · 定量生物学 2026-01-22 Joshua Looker , Kat S. Rock , Louise Dyson

The timely identification of socio-economic sectors vulnerable to a disease outbreak presents an important challenge to the civic authorities and healthcare workers interested in outbreak mitigation measures. This problem was traditionally…

机器学习 · 计算机科学 2021-10-28 Aboli Marathe , Harsh Sakhrani , Saloni Parekh

Understanding how epidemics spread in a system is a crucial step to prevent and control outbreaks, with broad implications on the system's functioning, health, and associated costs. This can be achieved by identifying the elements at higher…

物理与社会 · 物理学 2015-03-16 Eugenio Valdano , Chiara Poletto , Armando Giovannini , Diana Palma , Lara Savini , Vittoria Colizza

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

机器学习 · 计算机科学 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

Epidemiologists use a variety of statistical algorithms for the early detection of outbreaks. The practical usefulness of such methods highly depends on the trade-off between the detection rate of outbreaks and the chances of raising a…

机器学习 · 计算机科学 2019-07-18 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

Out-of-distribution (OOD) detection is essential for determining when a supervised model encounters inputs that differ meaningfully from its training distribution. While widely studied in classification, OOD detection for regression and…

机器学习 · 统计学 2025-12-16 Min Lu , Hemant Ishwaran

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

种群与进化 · 定量生物学 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…

物理与社会 · 物理学 2018-10-11 Samuel V. Scarpino , Giovanni Petri
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