相关论文: scRDiT: Generating single-cell RNA-seq data by dif…

Diffusion model, as a new generative model which is very popular in image generation and audio synthesis, is rarely used in speech enhancement. In this paper, we use the diffusion model as a module for stochastic refinement. We propose…

This paper introduces the Single-Cell Perturbation Prediction Diffusion Model (scPPDM), the first diffusion-based framework for single-cell drug-response prediction from scRNA-seq data. scPPDM couples two condition channels,…

Diffusion Transformer (DiT), an emerging diffusion model for visual generation, has demonstrated superior performance but suffers from substantial computational costs. Our investigations reveal that these costs primarily stem from the…

Dataset distillation enables the training of deep neural networks with comparable performance in significantly reduced time by compressing large datasets into small and representative ones. Although the introduction of generative models has…

In this paper, we propose to utilise diffusion models for data augmentation in speech emotion recognition (SER). In particular, we present an effective approach to utilise improved denoising diffusion probabilistic models (IDDPM) to…

The lack of real-world data in clinical fields poses a major obstacle in training effective AI models for diagnostic and preventive tools in medicine. Generative AI has shown promise in increasing data volume and enhancing model training,…

Generating samples from a probability distribution is a fundamental task in machine learning and statistics. This article proposes a novel scheme for sampling from a distribution for which the probability density $\mu({\bf x})$ for ${\bf…

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Single-cell RNA sequencing (scRNA-seq) enables the study of cellular diversity at single cell level. It provides a global view of cell-type specification during the onset of biological mechanisms such as developmental processes and human…

Motivation: Single cell RNA sequencing (scRNA-seq) data makes studying the development of cells possible at unparalleled resolution. Given that many cellular differentiation processes are hierarchical, their scRNA-seq data is expected to be…

Recently, ultra high-throughput sequencing of RNA (RNA-Seq) has been developed as an approach for analysis of gene expression. By obtaining tens or even hundreds of millions of reads of transcribed sequences, an RNA-Seq experiment can offer…

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Diffusion models with their powerful expressivity and high sample quality have achieved State-Of-The-Art (SOTA) performance in the generative domain. The pioneering Vision Transformer (ViT) has also demonstrated strong modeling capabilities…

In the visual generative area, discrete diffusion models are gaining traction for their efficiency and compatibility. However, pioneered attempts still fall behind their continuous counterparts, which we attribute to noise (absorbing state)…

Single image super-resolution (SISR) aims to reconstruct high-resolution (HR) images from the given low-resolution (LR) ones, which is an ill-posed problem because one LR image corresponds to multiple HR images. Recently, learning-based…

We introduce a novel generative model, the Discrete Distribution Networks (DDN), that approximates data distribution using hierarchical discrete distributions. We posit that since the features within a network inherently capture…

The ability to measure the transcriptomes of single cells has only been feasible for a few years, and is becoming an extremely popular assay. While many types of analysis and questions can be answered using single cell RNA-sequencing, a…

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering…