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Alzheimer's disease (AD) is an irreversible and progressive brain disease that can be stopped or slowed down with medical treatment. Language changes serve as a sign that a patient's cognitive functions have been impacted, potentially…

计算与语言 · 计算机科学 2018-04-19 Sweta Karlekar , Tong Niu , Mohit Bansal

Memory disorders are a central factor in the decline of functioning and daily activities in elderly individuals. The confirmation of the illness, initiation of medication to slow its progression, and the commencement of occupational therapy…

声音 · 计算机科学 2024-02-08 Marko Niemelä , Mikaela von Bonsdorff , Sami Äyrämö , Tommi Kärkkäinen

Parkinson's disease (PD) poses a growing global health challenge, with Bangladesh experiencing a notable rise in PD-related mortality. Early detection of PD remains particularly challenging in resource-constrained settings, where…

Neurodegeneration characterizes individuals with different dementia subtypes (e.g., individuals with Alzheimer's Disease, Primary Progressive Aphasia, and Parkinson's Disease), leading to progressive decline in cognitive, linguistic, and…

计算与语言 · 计算机科学 2022-12-06 Charalambos Themistocleous

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

机器学习 · 计算机科学 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

Parkinson's disease (PD), characterized by its incurable nature, rapid progression, and severe disability, poses significant challenges to the lives of patients and their families. Given the aging population, the need for early detection of…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Wei Huang , Yinxuan Xu , Yintao Zhou , Zhengyu Li , Jing Huang , Meng Pang

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

神经元与认知 · 定量生物学 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks…

机器学习 · 计算机科学 2019-11-26 James Wingate , Ilianna Kollia , Luc Bidaut , Stefanos Kollias

Parkinson's Disease (PD) is a slowly evolving neuro-logical disease that affects about 1% of the population above 60 years old, causing symptoms that are subtle at first, but whose intensity increases as the disease progresses. Automated…

Alzheimer's Disease (AD) is a significant and growing public health concern. Investigating alterations in speech and language patterns offers a promising path towards cost-effective and non-invasive early detection of AD on a large scale.…

计算与语言 · 计算机科学 2024-12-23 Jonathan Heitz , Gerold Schneider , Nicolas Langer

In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a…

机器学习 · 计算机科学 2016-02-24 Giancarlo Crocetti , Michael Coakley , Phil Dressner , Wanda Kellum , Tamba Lamin

Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…

计算与语言 · 计算机科学 2021-09-27 Akshay Valsaraj , Ithihas Madala , Nikhil Garg , Veeky Baths

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

机器学习 · 计算机科学 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…

声音 · 计算机科学 2025-02-19 Yifan Gao , Long Guo , Hong Liu

Dysarthria is a speech disorder characterized by impaired intelligibility and reduced communicative effectiveness. Automatic dysarthria assessment provides a scalable, cost-effective approach for supporting the diagnosis and treatment of…

音频与语音处理 · 电气工程与系统科学 2025-11-05 Kaimeng Jia , Minzhu Tu , Zengrui Jin , Siyin Wang , Chao Zhang

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

计算与语言 · 计算机科学 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

机器学习 · 计算机科学 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations…

机器学习 · 计算机科学 2025-10-21 Arianna Francesconi , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Valerio Guarrasi , Rosa Sicilia