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Heart failure is a serious and life-threatening condition that can lead to elevated pressure in the left ventricle. Pulmonary Arterial Wedge Pressure (PAWP) is an important surrogate marker indicating high pressure in the left ventricle.…

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

定量方法 · 定量生物学 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

Heart failure is a debilitating condition that affects millions of people worldwide and has a significant impact on their quality of life and mortality rates. An objective assessment of cardiac pressures remains an important method for the…

机器学习 · 计算机科学 2023-09-12 Hyewon Jeong , Collin M. Stultz , Marzyeh Ghassemi

Mean aortic pressure (MAP) is a major determinant of perfusion in all organs systems. The ability to forecast MAP would enhance the ability of physicians to estimate prognosis of the patient and assist in early detection of hemodynamic…

机器学习 · 计算机科学 2020-10-20 Eliza Huang , Rui Wang , Uma Chandrasekaran , Rose Yu

Continuous cardiovascular monitoring can play a key role in precision health. However, some fundamental cardiac biomarkers of interest, including stroke volume and cardiac output, require invasive measurements, e.g., arterial pressure…

Early identification of high risk heart failure (HF) patients is key to timely allocation of life-saving therapies. Hemodynamic assessments can facilitate risk stratification and enhance understanding of HF trajectories. However, risk…

机器学习 · 计算机科学 2023-06-13 Josephine Lamp , Yuxin Wu , Steven Lamp , Prince Afriyie , Kenneth Bilchick , Lu Feng , Sula Mazimba

Right Heart Catheterization is a gold standard procedure for diagnosing Pulmonary Hypertension by measuring mean Pulmonary Artery Pressure (mPAP). It is invasive, costly, time-consuming and carries risks. In this paper, for the first time,…

图像与视频处理 · 电气工程与系统科学 2024-09-13 Michal K. Grzeszczyk , Przemysław Korzeniowski , Samer Alabed , Andrew J. Swift , Tomasz Trzciński , Arkadiusz Sitek

Pulmonary Hypertension (PH) is a severe disease characterized by an elevated pulmonary artery pressure. The gold standard for PH diagnosis is measurement of mean Pulmonary Artery Pressure (mPAP) during an invasive Right Heart…

图像与视频处理 · 电气工程与系统科学 2023-12-25 Michal K. Grzeszczyk , Tadeusz Satlawa , Angela Lungu , Andrew Swift , Andrew Narracott , Rod Hose , Tomasz Trzcinski , Arkadiusz Sitek

Heart failure (HF) is one of the most prevalent life-threatening cardiovascular diseases in which 6.5 million people are suffering in the USA and more than 23 million worldwide. Mechanical circulatory support of HF patients can be achieved…

机器学习 · 计算机科学 2023-01-20 Masoud Fetanat , Michael Stevens , Pankaj Jain , Christopher Hayward , Erik Meijering , Nigel H. Lovell

The early detection of a pulmonary embolism (PE) is critical for enhancing patient survival rates. Both image-based and non-image-based features are of utmost importance in medical classification tasks. In a clinical setting, physicians…

图像与视频处理 · 电气工程与系统科学 2024-04-18 Zhaoxin Guo , Zhipeng Wang , Ruiquan Ge , Jianxun Yu , Feiwei Qin , Yuan Tian , Yuqing Peng , Yonghong Li , Changmiao Wang

Accurate cardiac output (CO) estimation from photoplethysmography (PPG) is promising for unobtrusive hemodynamic monitoring, but remains difficult since CO is jointly determined by cardiac function and vascular tone. Conventional…

医学物理 · 物理学 2026-05-20 Yaowen Zhang , Bo Cui , Libera Fresiello , Peter H. Veltink , Dirk W. Donker , Ying Wang

Cardiovascular diseases are one of the most severe causes of mortality, taking a heavy toll of lives annually throughout the world. The continuous monitoring of blood pressure seems to be the most viable option, but this demands an invasive…

信号处理 · 电气工程与系统科学 2022-09-27 Nabil Ibtehaz , Sakib Mahmud , Muhammad E. H. Chowdhury , Amith Khandakar , Mohamed Arselene Ayari , Anas Tahir , M. Sohel Rahman

Pulmonary embolism (PE) is a life-threatening condition where rapid and accurate diagnosis is imperative yet difficult due to predominantly atypical symptomatology. Computed tomography pulmonary angiography (CTPA) is acknowledged as the…

图像与视频处理 · 电气工程与系统科学 2024-07-17 Bizhe Bai , Yan-Jie Zhou , Yujian Hu , Tony C. W. Mok , Yilang Xiang , Le Lu , Hongkun Zhang , Minfeng Xu

Ischemic heart disease is the highest cause of mortality globally each year. This not only puts a massive strain on the lives of those affected but also on the public healthcare systems. To understand the dynamics of the healthy and…

机器学习 · 计算机科学 2021-02-25 Eoin Brophy , Maarten De Vos , Geraldine Boylan , Tomas Ward

The effectiveness of a cardiovascular magnetic resonance (CMR) scan depends on the ability of the operator to correctly tune the acquisition parameters to the subject being scanned and on the potential occurrence of imaging artefacts such…

The use of observed wearable sensor data (e.g., photoplethysmograms [PPG]) to infer health measures (e.g., glucose level or blood pressure) is a very active area of research. Such technology can have a significant impact on health…

信号处理 · 电气工程与系统科学 2023-05-01 Suril Mehta , Nipun Kwatra , Mohit Jain , Daniel McDuff

Purpose: Chest X-rays are essential for diagnosing pulmonary conditions, but limited access in resource-constrained settings can delay timely diagnosis. Electrocardiograms (ECGs), in contrast, are widely available, non-invasive, and often…

信号处理 · 电气工程与系统科学 2025-09-23 Julia Matejas , Olaf Żurawski , Nils Strodthoff , Juan Miguel Lopez Alcaraz

Accurate noninvasive estimation of intracranial pressure (ICP) remains a major challenge in critical care. We developed a bespoke machine learning algorithm that integrates system identification and ranking-constrained optimization to…

Pulmonary arterial hypertension (PAH) is a progressive cardiopulmonary disease that leads to increased pulmonary pressures, vascular remodeling, and eventual right ventricular (RV) failure. Pediatric PAH remains understudied due to limited…

In modern assembly pipelines, identifying anomalies is crucial in ensuring product quality and operational efficiency. Conventional single-modality methods fail to capture the intricate relationships required for precise anomaly prediction…

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