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The management of invasive mechanical ventilation, and the regulation of sedation and analgesia during ventilation, constitutes a major part of the care of patients admitted to intensive care units. Both prolonged dependence on mechanical…

人工智能 · 计算机科学 2017-04-24 Niranjani Prasad , Li-Fang Cheng , Corey Chivers , Michael Draugelis , Barbara E Engelhardt

Mechanical ventilation is one of the most widely used therapies in the ICU. However, despite broad application from anaesthesia to COVID-related life support, many injurious challenges remain. We frame these as a control problem:…

Mechanical ventilation is a key form of life support for patients with pulmonary impairment. Healthcare workers are required to continuously adjust ventilator settings for each patient, a challenging and time consuming task. Hence, it would…

Invasive mechanical ventilation (MV) is a life-sustaining therapy commonly used in the intensive care unit (ICU) for patients with severe and acute conditions. These patients frequently rely on MV for breathing. Given the high risk of death…

机器学习 · 计算机科学 2026-01-16 Muhammad Hamza Yousuf , Jason Li , Sahar Vahdati , Raphael Theilen , Jakob Wittenstein , Jens Lehmann

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

机器学习 · 计算机科学 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Offline reinforcement learning (RL) holds great promise for deriving optimal policies from observational data, but challenges related to interpretability and evaluation limit its practical use in safety-critical domains. Interpretability is…

机器学习 · 计算机科学 2025-07-24 Anton Matsson , Yaochen Rao , Heather J. Litman , Fredrik D. Johansson

Reinforcement learning (RL) has been widely applied to sequential decision making, where interpretability and performance are both critical for practical adoption. Current approaches typically focus on performance and rely on post hoc…

机器学习 · 计算机科学 2025-10-07 Qianxin Yi , Shao-Bo Lin , Jun Fan , Yao Wang

We propose a method to capture the handling abilities of fast jet pilots in a software model via reinforcement learning (RL) from human preference feedback. We use pairwise preferences over simulated flight trajectories to learn an…

人工智能 · 计算机科学 2023-05-29 Tom Bewley , Jonathan Lawry , Arthur Richards

Although deep reinforcement learning has become a promising machine learning approach for sequential decision-making problems, it is still not mature enough for high-stake domains such as autonomous driving or medical applications. In such…

机器学习 · 计算机科学 2022-02-25 Claire Glanois , Paul Weng , Matthieu Zimmer , Dong Li , Tianpei Yang , Jianye Hao , Wulong Liu

Mechanical ventilation (MV) is a life-saving intervention for patients with acute respiratory failure (ARF) in the ICU. However, inappropriate ventilator settings could cause ventilator-induced lung injury (VILI). Also, clinicians workload…

This paper is a study of reinforcement learning (RL) as an optimal-control strategy for control of nonlinear valves. It is evaluated against the PID (proportional-integral-derivative) strategy, using a unified framework. RL is an autonomous…

机器学习 · 计算机科学 2021-02-05 Rajesh Siraskar

This paper demonstrates that continual relearning of control policies using incremental deep reinforcement learning (RL) can improve policy learning for non-stationary processes. We demonstrate this approach for a data-driven 'smart…

机器学习 · 计算机科学 2020-08-06 Avisek Naug , Marcos Quiñones-Grueiro , Gautam Biswas

Rationing of healthcare resources is a challenging decision that policy makers and providers may be forced to make during a pandemic, natural disaster, or mass casualty event. Well-defined guidelines to triage scarce life-saving resources…

机器学习 · 计算机科学 2024-11-12 Julien Grand-Clément , You Hui Goh , Carri Chan , Vineet Goyal , Elizabeth Chuang

Patients with severe Coronavirus disease 19 (COVID-19) typically require supplemental oxygen as an essential treatment. We developed a machine learning algorithm, based on a deep Reinforcement Learning (RL), for continuous management of…

机器学习 · 计算机科学 2021-11-09 Hua Zheng , Jiahao Zhu , Wei Xie , Judy Zhong

Our aim is to establish a framework where reinforcement learning (RL) of optimizing interventions retrospectively allows us a regulatory compliant pathway to prospective clinical testing of the learned policies in a clinical deployment. We…

机器学习 · 计算机科学 2020-03-20 Luchen Li , Ignacio Albert-Smet , Aldo A. Faisal

In this paper, three recently introduced reinforcement learning (RL) methods are used to generate human-interpretable policies for the cart-pole balancing benchmark. The novel RL methods learn human-interpretable policies in the form of…

机器学习 · 计算机科学 2020-07-21 Daniel Hein , Steffen Limmer , Thomas A. Runkler

Reinforcement learning (RL) has the potential to significantly improve clinical decision making. However, treatment policies learned via RL from observational data are sensitive to subtle choices in study design. We highlight a simple…

机器学习 · 计算机科学 2020-12-23 Christina X. Ji , Michael Oberst , Sanjat Kanjilal , David Sontag

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

机器学习 · 计算机科学 2024-09-10 Jinzhi Shen , Ke Ma

The use of reinforcement learning (RL) methods to support health behavior change via personalized and just-in-time adaptive interventions is of significant interest to health and behavioral science researchers focused on problems such as…

机器学习 · 计算机科学 2025-07-08 Karine Karine , Benjamin M. Marlin
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