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This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

机器学习 · 计算机科学 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Prototype-based classification learning methods are known to be inherently interpretable. However, this paradigm suffers from major limitations compared to deep models, such as lower performance. This led to the development of the so-called…

机器学习 · 计算机科学 2025-04-18 Sascha Saralajew , Ashish Rana , Thomas Villmann , Ammar Shaker

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Yuzhe Lu , Adam Perer

Image recognition with prototypes is considered an interpretable alternative for black box deep learning models. Classification depends on the extent to which a test image "looks like" a prototype. However, perceptual similarity for humans…

计算机视觉与模式识别 · 计算机科学 2022-08-18 Meike Nauta , Annemarie Jutte , Jesper Provoost , Christin Seifert

XAI gained considerable importance in recent years. Methods based on prototypical case-based reasoning have shown a promising improvement in explainability. However, these methods typically rely on additional post-hoc saliency techniques to…

计算机视觉与模式识别 · 计算机科学 2025-10-02 Steffen Meinert , Philipp Schlinge , Nils Strodthoff , Martin Atzmueller

Prototype-based interpretability methods provide intuitive explanations of model prediction by comparing samples to a reference set of memorized exemplars or typical representatives in terms of similarity. In the field of sequential data…

机器学习 · 计算机科学 2023-03-20 Yifei Zhang , Neng Gao , Cunqing Ma

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

图像与视频处理 · 电气工程与系统科学 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

机器学习 · 计算机科学 2020-08-14 Anika Tabassum , Naimul Khan

Recently, deep learning models have shown the potential to predict breast cancer risk and enable targeted screening strategies, but current models do not consider the change in the breast over time. In this paper, we present a new method,…

计算机视觉与模式识别 · 计算机科学 2023-08-29 Hyeonsoo Lee , Junha Kim , Eunkyung Park , Minjeong Kim , Taesoo Kim , Thijs Kooi

Recent advancements in post-hoc and inherently interpretable methods have markedly enhanced the explanations of black box classifier models. These methods operate either through post-analysis or by integrating concept learning during model…

计算机视觉与模式识别 · 计算机科学 2024-04-24 Bor-Shiun Wang , Chien-Yi Wang , Wei-Chen Chiu

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

图像与视频处理 · 电气工程与系统科学 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

One of the major challenges in machine learning nowadays is to provide predictions with not only high accuracy but also user-friendly explanations. Although in recent years we have witnessed increasingly popular use of deep neural networks…

机器学习 · 计算机科学 2019-07-24 Yao Ming , Panpan Xu , Huamin Qu , Liu Ren

Interpretability is critical in high-stakes domains such as medical imaging, where understanding model decisions is essential for clinical adoption. In this work, we introduce Sparse Autoencoder (SAE)-based interpretability to breast…

计算机视觉与模式识别 · 计算机科学 2025-08-19 Krishna Kanth Nakka

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

生物大分子 · 定量生物学 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

机器学习 · 计算机科学 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Explainable AI (XAI) methods generally fall into two categories. Post-hoc approaches generate explanations for pre-trained models and are compatible with various neural network architectures. These methods often use feature importance…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Piotr Borycki , Magdalena Trędowicz , Szymon Janusz , Jacek Tabor , Przemysław Spurek , Arkadiusz Lewicki , Łukasz Struski

The ability to accurately estimate risk of developing breast cancer would be invaluable for clinical decision-making. One promising new approach is to integrate image-based risk models based on deep neural networks. However, one must take…

图像与视频处理 · 电气工程与系统科学 2020-09-17 Yue Liu , Hossein Azizpour , Fredrik Strand , Kevin Smith

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Neil Chaudhary , Zaynah Dhunny

Explainable Artificial Intelligence (xAI) has the potential to enhance the transparency and trust of AI-based systems. Although accurate predictions can be made using Deep Neural Networks (DNNs), the process used to arrive at such…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Bhushan Atote , Victor Sanchez

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

图像与视频处理 · 电气工程与系统科学 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah