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Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

Computational Fluid Dynamics (CFD) simulation by the numerical solution of the Navier-Stokes equations is an essential tool in a wide range of applications from engineering design to climate modeling. However, the computational cost and…

计算物理 · 物理学 2021-11-29 Mateus Dias Ribeiro , Abdul Rehman , Sheraz Ahmed , Andreas Dengel

The heart is the central part of the cardiovascular network. Its role is to pump blood to various body organs. Many cardiovascular diseases occur due to an abnormal functioning of the heart. A diseased heart leads to severe complications…

医学物理 · 物理学 2024-11-19 Mahesh S. Nagargoje , Eneko Lazpita , Jesús Garicano-Mena , Soledad Le Clainche

4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

图像与视频处理 · 电气工程与系统科学 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

计算机视觉与模式识别 · 计算机科学 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Widefield calcium imaging has recently emerged as a powerful experimental technique to record coordinated large-scale brain activity. These measurements present a unique opportunity to characterize spatiotemporal coherent structures that…

The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through…

流体动力学 · 物理学 2024-02-21 Hashnayne Ahmed , Chinmayee Podder

An arteriovenous fistula, created by artificially connecting segments of a patient's vasculature, is the preferred way to gain access to the bloodstream for kidney dialysis. The increasing power and availability of supercomputing…

医学物理 · 物理学 2021-06-14 J. W. S. McCullough , P. V. Coveney

Coronary heart disease (CHD) remains a top reason of mortality worldwide. This study introduces a novel approach by integrating patient-specific Multi-slice CT scans into CAD models and employing a one-dimensional numerical framework to…

医学物理 · 物理学 2025-07-01 Oeshee Roy , Priyanshu Ghosh , Sayan Karmakar , Supratim Saha

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

流体动力学 · 物理学 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

计算工程、金融与科学 · 计算机科学 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu

This study investigates the effects of geometric model reduction on blood flow simulations in the patient-specific descending aorta, followed by speed-accuracy trade-off analysis using 3D simulations. We demonstrate how wall shear stresses…

流体动力学 · 物理学 2025-12-12 Rishi Kumar , K. Muralidhar , Indranil Saha Dalal

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

We propose a method for multi-scale hybrid simulations of molecular dynamics (MD) and computational fluid dynamics (CFD). In the method, usual lattice-mesh based simulations are applied for CFD level, but each lattice is associated with a…

软凝聚态物质 · 物理学 2014-01-20 Shugo Yasuda , Ryoichi Yamamoto

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Rapid and accurate simulation of cerebral aneurysm flow modifications by flow diverters (FDs) can help improving patient-specific intervention and predicting treatment outcome. However, with explicit FD devices being placed in…

流体动力学 · 物理学 2021-06-14 Armin Abdehkakha , Adam L. Hammond , Tatsat R. Patel , Adnan H. Siddiqui , Gary Dargush , Hui Meng

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

定量方法 · 定量生物学 2025-08-27 Daehyun Kim , Jeffrey Tithof

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

计算工程、金融与科学 · 计算机科学 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

Computational fluid dynamics (CFD) simulation provides valuable information on blood flow from the vascular geometry. However, it requires extracting precise models of arteries from low-resolution medical images, which remains challenging.…

计算几何 · 计算机科学 2023-06-14 Méghane Decroocq , Carole Frindel , Pierre Rougé , Makoto Ohta , Guillaume Lavoué