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Synchronous oscillatory dynamics is frequently observed in the human brain. We analyze the fine temporal structure of phase-locking in a realistic network model and match it with the experimental data from parkinsonian patients. We show…

神经元与认知 · 定量生物学 2011-04-18 Choongseok Park , Robert M. Worth , Leonid L. Rubchinsky

Spontaneous brain activity generically displays transient spatiotemporal coherent structures, which can selectively be affected in various neurological and psychiatric pathologies. Here we model the full brain's electroencephalographic…

神经元与认知 · 定量生物学 2025-02-25 Annalisa Caligiuri , David Papo , Görsev Yener , Bahar Güntekin , Tobias Galla , Lucas Lacasa , Massimiliano Zanin

We present a novel topological framework for analyzing functional brain signals using time-frequency analysis. By integrating persistent homology with time-frequency representations, we capture multi-scale topological features that…

神经元与认知 · 定量生物学 2025-04-23 Moo K. Chung , Aaron F. Struck

The various human brain tasks are performed at different locations and time scales. Yet, we discovered the existence of time-invariant (above an essential time scale) partitioning of the brain activity into personal state-specific frequency…

医学物理 · 物理学 2009-11-11 Itai Doron , Eyal Hulata , Itay Baruchi , Vernon L. Towle , Eshel Ben-Jacob

Adaptive behavior, cognition and emotion are the result of a bewildering variety of brain spatiotemporal activity patterns. An important problem in neuroscience is to understand the mechanism by which the human brain's 100 billion neurons…

Brain rhythms contribute to every aspect of brain function. Here, we study critical and resonance phenomena that precede the emergence of brain rhythms. Using an analytical approach and simulations of a cortical circuit model of neural…

无序系统与神经网络 · 物理学 2015-06-12 A. V. Goltsev , M. A. Lopes , K. -E. Lee , J. F. F. Mendes

As a person learns a new skill, distinct synapses, brain regions, and circuits are engaged and change over time. In this paper, we develop methods to examine patterns of correlated activity across a large set of brain regions. Our goal is…

神经元与认知 · 定量生物学 2013-10-31 Danielle S. Bassett , Nicholas F. Wymbs , M. Puck Rombach , Mason A. Porter , Peter J. Mucha , Scott T. Grafton

Our current understanding of brain rhythms is based on quantifying their instantaneous or time-averaged characteristics. What remains unexplored, is the actual structure of the waves -- their shapes and patterns over finite timescales. To…

神经元与认知 · 定量生物学 2022-05-10 Clarissa Hoffman , Jingheng Cheng , Daoyun Ji , Y. Dabaghian

The brain criticality hypothesis has largely only characterized brain dynamics in terms of their self-similarity, although experimental evidence suggests that the brain exhibits significant multifractality. To understand how multifractality…

无序系统与神经网络 · 物理学 2026-02-03 Merlin Dumeur , Sheng H. Wang , J. Matias Palva , Philippe Ciuciu

Synchronization in neural system plays an important role in many brain functions. Synchronization in the gamma frequency band (30Hz-100Hz) is involved in a variety of cognitive phenomena; abnormalities of the gamma synchronization are found…

神经元与认知 · 定量生物学 2021-04-26 Quynh-Anh Nguyen , Leonid L Rubchinsky

Neural synchronization is believed to be critical for many brain functions. It frequently exhibits temporal variability, but it is not known if this variability has a specific temporal patterning. This study explores these…

神经元与认知 · 定量生物学 2013-03-11 Sungwoo Ahn , Leonid L. Rubchinsky

Loss of cortical integration and changes in the dynamics of electrophysiological brain signals characterize the transition from wakefulness towards unconsciousness. The common mechanism underlying these observations remains unknown. In this…

The functioning of an organ such as the brain emerges from interactions between its constituent parts. Further, this interaction is not immutable in time but rather unfolds in a succession of patterns, thereby allowing the brain to adapt to…

神经元与认知 · 定量生物学 2021-06-02 Emmanuelle Tognoli , Daniela Benites , J. A. Scott Kelso

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

神经元与认知 · 定量生物学 2022-07-19 Yan-Liang Shi , Roxana Zeraati , Anna Levina , Tatiana A. Engel

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…

神经元与认知 · 定量生物学 2026-01-21 Roxana Zeraati , Anna Levina , Jakob H. Macke , Richard Gao

The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…

统计力学 · 物理学 2022-07-08 Guillermo B. Morales , Serena Di Santo , Miguel A. Munoz

The brain is organized in a modular way, serving multiple functionalities. This multiplicity requires that both positive (e.g. excitatory, phase-coherent) and negative (e.g. inhibitory, phase-opposing) interactions take place across brain…

神经元与认知 · 定量生物学 2019-07-29 Assaf Almog , Ori Roethler , Renate Buijink , Stephan Michel , Johanna H Meijer , Jos H. T. Rohling , Diego Garlaschelli

Functional magnetic resonance imaging (fMRI) data provides information concerning activity in the brain and in particular the interactions between brain regions. Resting state fMRI data is widely used for inferring connectivities in the…

应用统计 · 统计学 2019-03-04 Christina Stoehr , John A D Aston , Claudia Kirch

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

神经元与认知 · 定量生物学 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan
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