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Decrypting intelligence from the human brain construct is vital in the detection of particular neurological disorders. Recently, functional brain connectomes have been used successfully to predict behavioral scores. However,…

神经元与认知 · 定量生物学 2022-09-28 Imen Jegham , Islem Rekik

Effective connectivity can describe the causal patterns among brain regions. These patterns have the potential to reveal the pathological mechanism and promote early diagnosis and effective drug development for cognitive disease. However,…

计算机视觉与模式识别 · 计算机科学 2024-06-04 Qiankun Zuo , Hao Tian , Chi-Man Pun , Hongfei Wang , Yudong Zhang , Jin Hong

Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…

社会与信息网络 · 计算机科学 2020-06-11 Tommaso Lanciano , Francesco Bonchi , Aristides Gionis

Graph neural networks (GNNs) provide powerful insights for brain neuroimaging technology from the view of graphical networks. However, most existing GNN-based models assume that the neuroimaging-produced brain connectome network is a…

机器学习 · 计算机科学 2022-09-30 Gen Shi , Yifan Zhu , Wenjin Liu , Quanming Yao , Xuesong Li

Studying influential nodes (I-nodes) in brain networks is of great significance in the field of brain imaging. Most existing studies consider brain connectivity hubs as I-nodes. However, this approach relies heavily on prior knowledge from…

神经元与认知 · 定量生物学 2024-09-18 Yanqing Kang , Di Zhu , Haiyang Zhang , Enze Shi , Sigang Yu , Jinru Wu , Xuhui Wang , Xuan Liu , Geng Chen , Xi Jiang , Tuo Zhang , Shu Zhang

Under the framework of network-based neurodegeneration, brain functional connectome (FC)-based Graph Neural Networks (GNN) have emerged as a valuable tool for the diagnosis and prognosis of neurodegenerative diseases such as Alzheimer's…

神经元与认知 · 定量生物学 2023-07-14 Zijian Dong , Yilei Wu , Yu Xiao , Joanna Su Xian Chong , Yueming Jin , Juan Helen Zhou

Learning how to estimate a connectional brain template(CBT) from a population of brain multigraphs, where each graph (e.g., functional) quantifies a particular relationship between pairs of brain regions of interest (ROIs), allows to pin…

机器学习 · 计算机科学 2021-10-08 Oytun Demirbilek , Islem Rekik

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

机器学习 · 计算机科学 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Graph neural networks (GNNs) have demonstrated great success in representation learning for graph-structured data. The layer-wise graph convolution in GNNs is shown to be powerful at capturing graph topology. During this process, GNNs are…

机器学习 · 计算机科学 2021-12-10 Mingxuan Ju , Shifu Hou , Yujie Fan , Jianan Zhao , Liang Zhao , Yanfang Ye

Alzheimer's disease (AD) is a neurodegenerative disorder that affects more than seven million people in the United States alone. AD currently has no cure, but there are ways to potentially slow its progression if caught early enough. In…

计算机视觉与模式识别 · 计算机科学 2026-04-09 Mahdi Moghaddami , Mohammad-Reza Siadat , Austin Toma , Connor Laming , Huirong Fu

Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…

机器学习 · 计算机科学 2025-09-24 Niharika Tewari , Nguyen Linh Dan Le , Mujie Liu , Jing Ren , Ziqi Xu , Tabinda Sarwar , Veeky Baths , Feng Xia

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

定量方法 · 定量生物学 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

Functional magnetic resonance imaging (fMRI) is one of the most common imaging modalities to investigate brain functions. Recent studies in neuroscience stress the great potential of functional brain networks constructed from fMRI data for…

机器学习 · 计算机科学 2022-05-31 Xuan Kan , Hejie Cui , Joshua Lukemire , Ying Guo , Carl Yang

Graph Neural Networks (GNNs) have emerged as a powerful tool to learn from graph-structured data. A paramount example of such data is the brain, which operates as a network, from the micro-scale of neurons, to the macro-scale of regions.…

机器学习 · 计算机科学 2022-11-17 Ahmed ElGazzar , Rajat Thomas , Guido van Wingen

Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…

计算机视觉与模式识别 · 计算机科学 2025-07-31 Yuzhen Gao , Qianqian Wang , Yongheng Sun , Cui Wang , Yongquan Liang , Mingxia Liu

Exploring the complex structure of the human brain is crucial for understanding its functionality and diagnosing brain disorders. Thanks to advancements in neuroimaging technology, a novel approach has emerged that involves modeling the…

There is a recent trend to leverage the power of graph neural networks (GNNs) for brain-network based psychiatric diagnosis, which,in turn, also motivates an urgent need for psychiatrists to fully understand the decision behavior of the…

机器学习 · 统计学 2024-01-30 Kaizhong Zheng , Shujian Yu , Badong Chen

Objective: Multi-modal functional magnetic resonance imaging (fMRI) can be used to make predictions about individual behavioral and cognitive traits based on brain connectivity networks. Methods: To take advantage of complementary…

机器学习 · 计算机科学 2024-08-27 Gang Qu , Li Xiao , Wenxing Hu , Kun Zhang , Vince D. Calhoun , Yu-Ping Wang