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Backgrounds: Information extraction (IE) is critical in clinical natural language processing (NLP). While large language models (LLMs) excel on generative tasks, their performance on extractive tasks remains debated. Methods: We…

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

计算与语言 · 计算机科学 2023-12-12 Chris Solomou

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

计算与语言 · 计算机科学 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman

Recent advancements in large language models (LLMs) have shown promise in medical applications such as disease diagnosis and treatment planning. However, most existing medical LLMs struggle with the deep reasoning required for complex…

计算与语言 · 计算机科学 2025-07-31 Hongzhou Yu , Tianhao Cheng , Yingwen Wang , Wen He , Qing Wang , Ying Cheng , Yuejie Zhang , Rui Feng , Xiaobo Zhang

For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

计算与语言 · 计算机科学 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

The precipitous rise and adoption of Large Language Models (LLMs) have shattered expectations with the fastest adoption rate of any consumer-facing technology in history. Healthcare, a field that traditionally uses NLP techniques, was bound…

计算与语言 · 计算机科学 2023-10-10 Surjya Ray , Pratik Mehta , Hongen Zhang , Ada Chaman , Jian Wang , Chung-Jen Ho , Michael Chiou , Tashfeen Suleman

The rapid identification of medical emergencies through digital communication channels remains a critical challenge in modern healthcare delivery, particularly with the increasing prevalence of telemedicine. This paper presents a novel…

机器学习 · 计算机科学 2024-12-24 Ferit Akaybicen , Aaron Cummings , Lota Iwuagwu , Xinyue Zhang , Modupe Adewuyi

This study evaluates the performance of large language models (LLMs) and the HINT model in predicting clinical trial outcomes, focusing on metrics including Balanced Accuracy, Matthews Correlation Coefficient (MCC), Recall, and Specificity.…

机器学习 · 计算机科学 2025-03-19 Shuyi Jin , Lu Chen , Hongru Ding , Meijie Wang , Lun Yu

Self-healing systems have long been a focus of research, aiming to enable software to recover from unexpected runtime errors without human intervention. Traditional approaches rely on predefined heuristic rules, such as reusing error…

软件工程 · 计算机科学 2026-05-05 Zhensu Sun , Haotian Zhu , Bowen Xu , Xiaoning Du , Li Li , David Lo

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

计算与语言 · 计算机科学 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Artificial intelligence (AI) has shown the potential to revolutionize healthcare by improving diagnostic accuracy, optimizing workflows, and personalizing treatment plans. Large Language Models (LLMs) and Multimodal Large Language Models…

Large Language Models (LLMs) are increasingly adopted for applications in healthcare, reaching the performance of domain experts on tasks such as question answering and document summarisation. Despite their success on these tasks, it is…

计算与语言 · 计算机科学 2025-05-20 Aishik Nagar , Viktor Schlegel , Thanh-Tung Nguyen , Hao Li , Yuping Wu , Kuluhan Binici , Stefan Winkler

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

计算与语言 · 计算机科学 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

The integration of Large Language Models (LLMs) into healthcare holds significant potential to enhance diagnostic accuracy and support medical treatment planning. These AI-driven systems can analyze vast datasets, assisting clinicians in…

计算与语言 · 计算机科学 2025-04-15 Diogo Sousa , Guilherme Barbosa , Catarina Rocha , Dulce Oliveira

Fine-tuning Large Language Models (LLMs) incurs considerable training costs, driving the need for data-efficient training with optimised data ordering. Human-inspired strategies offer a solution by organising data based on human learning…

计算与语言 · 计算机科学 2024-11-06 Yushi Yang , Andrew M. Bean , Robert McCraith , Adam Mahdi

Clinical natural language processing (NLP) is increasingly in demand in both clinical research and operational practice. However, most of the state-of-the-art solutions are transformers-based and require high computational resources,…

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Large language models (LLMs) such as GPT-4o and o1 have demonstrated strong performance on clinical natural language processing (NLP) tasks across multiple medical benchmarks. Nonetheless, two high-impact NLP tasks - structured tabular…

The challenge of accessing historical patient data for clinical research, while adhering to privacy regulations, is a significant obstacle in medical science. An innovative approach to circumvent this issue involves utilising synthetic…

计算与语言 · 计算机科学 2024-03-15 Erlend Frayling , Jake Lever , Graham McDonald