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The prevalence of unhealthy eating habits has become an increasingly concerning issue in the United States. However, major food recommendation platforms (e.g., Yelp) continue to prioritize users' dietary preferences over the healthiness of…

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the "opioid crisis". The relationship between substance use and mental health has been extensively studied, with one possible relationship…

Dietary intake data are routinely drawn upon to explore diet-health relationships. However, these data are often subject to measurement error, distorting the true relationships. Beyond measurement error, there are likely complex synergistic…

The adoption of deep learning in healthcare is hindered by their "black box" nature. In this paper, we explore the RETAIN architecture for the task of glusose forecasting for diabetic people. By using a two-level attention mechanism, the…

机器学习 · 计算机科学 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in…

定量方法 · 定量生物学 2019-05-03 Jen J. Gong , Abigail Z. Jacobs , Toby E. Stuart , Mathijs de Vaan

Social media platforms have become valuable tools for understanding public health challenges by offering insights into patient behaviors, medication use, and mental health issues. However, analyzing such data remains difficult due to the…

社会与信息网络 · 计算机科学 2025-08-15 Muhammad Ahmad , Fida Ullah , Muhammad Usman , Ildar Batyrshin , Grigori Sidorov

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognised as a systemic disease characterised by coordinated dysfunction across metabolic, renal, lipid, and inflammatory pathways. Existing clinical assessments often fail to…

机器学习 · 计算机科学 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Avoiding out-of-distribution (OOD) data is critical for training supervised machine learning models in the medical imaging domain. Furthermore, obtaining labeled medical data is difficult and expensive since it requires expert annotators…

计算机视觉与模式识别 · 计算机科学 2022-10-05 Suraj Kothawade , Akshit Srivastava , Venkat Iyer , Ganesh Ramakrishnan , Rishabh Iyer

The excessive consumption of marijuana can induce substantial psychological and social consequences. In this investigation, we propose an elucidative framework termed high-order graph attention neural networks (HOGANN) for the…

神经元与认知 · 定量生物学 2024-09-10 Jun-En Ding , Shihao Yang , Anna Zilverstand , Kaustubh R. Kulkarni , Xiaosi Gu , Feng Liu

Metabolic disorders, particularly type 2 diabetes mellitus (T2DM), represent a significant global health burden, disproportionately impacting genetically predisposed populations such as the Pima Indians (a Native American tribe from south…

机器学习 · 计算机科学 2025-09-24 Iram Wajahat , Amritpal Singh , Fazel Keshtkar , Syed Ahmad Chan Bukhari

Understanding the neurobiology of opioid use disorder (OUD) using resting-state functional magnetic resonance imaging (rs-fMRI) may help inform treatment strategies to improve patient outcomes. Recent literature suggests time-frequency…

神经元与认知 · 定量生物学 2025-03-12 Ahmed Temtam , Megan A. Witherow , Liangsuo Ma , M. Shibly Sadique , F. Gerard Moeller , Khan M. Iftekharuddin

This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE)…

Our aging population increasingly suffers from multiple chronic diseases simultaneously, necessitating the comprehensive treatment of these conditions. Finding the optimal set of drugs for a combinatorial set of diseases is a combinatorial…

Substance use is a global issue that negatively impacts millions of persons who use drugs (PWUDs). In practice, identifying vulnerable PWUDs for efficient allocation of appropriate resources is challenging due to their complex use patterns…

Background: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan…

定量方法 · 定量生物学 2023-04-26 Chunyu Ma , Zhihan Zhou , Han Liu , David Koslicki

Dietary studies showed that dietary-related problem such as obesity is associated with other chronic diseases like hypertension, irregular blood sugar levels, and increased risk of heart attacks. The primary cause of these problems is poor…

计算机视觉与模式识别 · 计算机科学 2021-09-07 Ghalib Tahir , Chu Kiong Loo

Motivation: Predicting Drug-Target Interaction (DTI) is a well-studied topic in bioinformatics due to its relevance in the fields of proteomics and pharmaceutical research. Although many machine learning methods have been successfully…

定量方法 · 定量生物学 2021-07-14 Haiyang Wang , Guangyu Zhou , Siqi Liu , Jyun-Yu Jiang , Wei Wang

People with diabetes need insulin delivery to effectively manage their blood glucose levels, especially after meals, because their bodies either do not produce enough insulin or cannot fully utilize it. Accurate insulin delivery starts with…

系统与控制 · 电气工程与系统科学 2024-11-21 Hanyu Zeng , Hui Ji , Pengfei Zhou

Clinical dietary assessment can generate detailed but high-dimensional nutrient and food-group information that is difficult to translate quickly into counselling priorities. This paper proposes an explainable unsupervised-to-supervised…

定量方法 · 定量生物学 2026-05-12 Wing Yi Yu , Chun Yin Chiu

The opioid crisis remains one of the most daunting and complex public health problems in the United States. This study investigates the national epidemic by analyzing vulnerability profiles of three key factors: opioid-related mortality…