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Accurate tumor classification is essential for selecting effective treatments, but current methods have limitations. Standard tumor grading, which categorizes tumors based on cell differentiation, is not recommended as a stand-alone…

计算机视觉与模式识别 · 计算机科学 2025-02-11 Marianne Abémgnigni Njifon , Tobias Weber , Viktor Bezborodov , Tyll Krueger , Dominic Schuhmacher

Deep learning is expected to aid pathologists by automating tasks such as tumour segmentation. We aimed to develop one universal tumour segmentation model for histopathological images and examine its performance in different cancer types.…

Automatic thin-prep cytologic test (TCT) screening can assist pathologists in finding cervical abnormality towards accurate and efficient cervical cancer diagnosis. Current automatic TCT screening systems mostly involve abnormal cervical…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Zhenrong Shen , Manman Fei , Xin Wang , Jiangdong Cai , Sheng Wang , Lichi Zhang , Qian Wang

Histopathological image analysis is the gold standard to diagnose cancer. Carcinoma is a subtype of cancer that constitutes more than 80% of all cancer cases. Squamous cell carcinoma and adenocarcinoma are two major subtypes of carcinoma,…

图像与视频处理 · 电气工程与系统科学 2022-01-20 Swathi Prabhua , Keerthana Prasada , Antonio Robels-Kelly , Xuequan Lu

We present a novel formulation for the calibration of a biophysical tumor growth model from a single-time snapshot, MRI scan of a glioblastoma patient. Tumor growth models are typically nonlinear parabolic partial differential equations…

定量方法 · 定量生物学 2020-06-30 Klaudius Scheufele , Shashank Subramanian , Andreas Mang , George Biros , Miriam Mehl

Generative models have been very successful over the years and have received significant attention for synthetic data generation. As deep learning models are getting more and more complex, they require large amounts of data to perform…

图像与视频处理 · 电气工程与系统科学 2023-02-24 Usama Tariq , Rizwan Qureshi , Anas Zafar , Danyal Aftab , Jia Wu , Tanvir Alam , Zubair Shah , Hazrat Ali

Cancer pathology is unique to a given individual, and developing personalized diagnostic and treatment protocols are a primary concern. Mathematical modeling and simulation is a promising approach to personalized cancer medicine. Yet, the…

组织与器官 · 定量生物学 2020-08-03 Alvaro Köhn-Luque , Xiaoran Lai , Arnoldo Frigessi

Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…

细胞行为 · 定量生物学 2015-05-20 Salvatore Torquato

Tumor data synthesis offers a promising solution to the shortage of annotated medical datasets. However, current approaches either limit tumor diversity by using predefined masks or employ computationally expensive two-stage processes with…

图像与视频处理 · 电气工程与系统科学 2025-06-02 Shengyuan Liu , Wenting Chen , Boyun Zheng , Wentao Pan , Xiang Li , Yixuan Yuan

In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation…

种群与进化 · 定量生物学 2013-03-22 Johannes G. Reiter , Ivana Bozic , Krishnendu Chatterjee , Martin A. Nowak

Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

图像与视频处理 · 电气工程与系统科学 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…

计算机视觉与模式识别 · 计算机科学 2025-09-04 Hongxu Yang , Edina Timko , Levente Lippenszky , Vanda Czipczer , Lehel Ferenczi

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

机器学习 · 计算机科学 2021-03-04 Takato Yasuno

Understanding how microenvironmental heterogeneity influences tumor progression is essential for advancing both cancer biology and therapeutic strategies. In this study, we develop a cellular automata (CA) model to simulate tumor growth…

细胞行为 · 定量生物学 2026-01-26 Yue Deng , Mingjing Li , Jinzhi Lei

Training computer-vision related algorithms on medical images for disease diagnosis or image segmentation is difficult due to the lack of training data, labeled samples, and privacy concerns. For this reason, a robust generative method to…

图像与视频处理 · 电气工程与系统科学 2021-11-04 Robert V Bergen , Jean-Francois Rajotte , Fereshteh Yousefirizi , Ivan S Klyuzhin , Arman Rahmim , Raymond T. Ng

AI-assisted imaging made substantial advances in tumor diagnosis and management. However, a major barrier to developing robust oncology foundation models is the scarcity of large-scale, high-quality annotated datasets, which are limited by…

This research presents a machine-learning approach for tumor detection in medical images using convolutional neural networks (CNNs). The study focuses on preprocessing techniques to enhance image features relevant to tumor detection,…

图像与视频处理 · 电气工程与系统科学 2024-03-01 Ha Anh Vu

Accurate lesion segmentation in whole-body PET/CT scans is crucial for cancer diagnosis and treatment planning, but limited datasets often hinder the performance of automated segmentation models. In this paper, we explore the potential of…

图像与视频处理 · 电气工程与系统科学 2024-09-13 Lap Yan Lennon Chan , Chenxin Li , Yixuan Yuan

AI requires extensive datasets, while medical data is subject to high data protection. Anonymization is essential, but poses a challenge for some regions, such as the head, as identifying structures overlap with regions of clinical…

We consider a missing data problem in the context of automatic segmentation methods for Magnetic Resonance Imaging (MRI) brain scans. Usually, automated MRI scan segmentation is based on multiple scans (e.g., T1-weighted, T2-weighted, T1CE,…

图像与视频处理 · 电气工程与系统科学 2024-05-06 Giulia Baldini , Melanie Schmidt , Charlotte Zäske , Liliana L. Caldeira