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Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

The predictive normalized maximum likelihood (pNML) approach has recently been proposed as the min-max optimal solution to the batch learning problem where both the training set and the test data feature are individuals, known sequences.…

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

Driven by applications in telecommunication networks, we explore the simulation task of estimating rare event probabilities for tandem queues in their steady state. Existing literature has recognized that importance sampling methods can be…

Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H\&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and…

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

Multimodal representation learning techniques typically rely on paired samples to learn common representations, but paired samples are challenging to collect in fields such as biology where measurement devices often destroy the samples.…

We propose a new formulation of Multiple-Instance Learning (MIL). In typical MIL settings, a unit of data is given as a set of instances called a bag and the goal is to find a good classifier of bags based on similarity from a single or…

Multi-scale resolution training has seen an increased adoption across multiple vision tasks, including classification and detection. Training with smaller resolutions enables faster training at the expense of a drop in accuracy. Conversely,…

We address the challenging problem of whole slide image (WSI) classification. WSIs have very high resolutions and usually lack localized annotations. WSI classification can be cast as a multiple instance learning (MIL) problem when only…

Continuous-time reinforcement learning (CTRL) provides a natural framework for sequential decision-making in dynamic environments where interactions evolve continuously over time. While CTRL has shown growing empirical success, its ability…

In this study, we derive Probably Approximately Correct (PAC) bounds on the asymptotic sample-complexity for RL within the infinite-horizon Markov Decision Process (MDP) setting that are sharper than those in existing literature. The…

Recently, multimodal contrastive learning (MMCL) approaches, such as CLIP, have achieved a remarkable success in learning representations that are robust against distribution shift and generalize to new domains. Despite the empirical…

In-Context Learning (ICL) empowers Large Language Models (LLMs) for rapid task adaptation without Fine-Tuning (FT), but its reliance on demonstration selection remains a critical challenge. While many-shot ICL shows promising performance…

Machine Learning models are increasingly used for decision making, in particular in high-stakes applications such as credit scoring, medicine or recidivism prediction. However, there are growing concerns about these models with respect to…

In the context of Multi Instance Learning, we analyze the Single Instance (SI) learning objective. We show that when the data is unbalanced and the family of classifiers is sufficiently rich, the SI method is a useful learning algorithm. In…

We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize…

The aim of multi-task reinforcement learning is two-fold: (1) efficiently learn by training against multiple tasks and (2) quickly adapt, using limited samples, to a variety of new tasks. In this work, the tasks correspond to reward…