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Multiple instance learning (MIL) is a powerful approach to classify whole slide images (WSIs) for diagnostic pathology. A fundamental challenge of MIL on WSI classification is to discover the \textit{critical instances} that trigger the bag…

计算机视觉与模式识别 · 计算机科学 2022-09-02 Zhikang Wang , Yue Bi , Tong Pan , Xiaoyu Wang , Chris Bain , Richard Bassed , Seiya Imoto , Jianhua Yao , Jiangning Song

Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

计算机视觉与模式识别 · 计算机科学 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

The development of computer vision solutions for gigapixel images in digital pathology is hampered by significant computational limitations due to the large size of whole slide images. In particular, digitizing biopsies at high resolutions…

计算机视觉与模式识别 · 计算机科学 2024-01-12 Rocío del Amor , Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

计算机视觉与模式识别 · 计算机科学 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Masked image modeling (MIM) performs strongly in pre-training large vision Transformers (ViTs). However, small models that are critical for real-world applications cannot or only marginally benefit from this pre-training approach. In this…

计算机视觉与模式识别 · 计算机科学 2023-01-04 Sucheng Ren , Fangyun Wei , Zheng Zhang , Han Hu

Introducing interpretability and reasoning into Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) analysis is challenging, given the complexity of gigapixel slides. Traditionally, MIL interpretability is limited to…

计算机视觉与模式识别 · 计算机科学 2024-05-21 Saarthak Kapse , Pushpak Pati , Srijan Das , Jingwei Zhang , Chao Chen , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras , Rajarsi R. Gupta , Prateek Prasanna

Hyperspectral image (HSI) classification presents unique challenges due to its high spectral dimensionality and limited labeled data. Traditional deep learning models often suffer from overfitting and high computational costs.…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Prachet Dev Singh , Shyamsundar Paramasivam , Sneha Barman , Mainak Singha , Ankit Jha , Girish Mishra , Biplab Banerjee

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

图像与视频处理 · 电气工程与系统科学 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

Multi-task learning (MTL) is to learn one single model that performs multiple tasks for achieving good performance on all tasks and lower cost on computation. Learning such a model requires to jointly optimize losses of a set of tasks with…

计算机视觉与模式识别 · 计算机科学 2020-09-25 Wei-Hong Li , Hakan Bilen

Multi-label image classification is a fundamental but challenging task towards general visual understanding. Existing methods found the region-level cues (e.g., features from RoIs) can facilitate multi-label classification. Nevertheless,…

计算机视觉与模式识别 · 计算机科学 2019-02-22 Yongcheng Liu , Lu Sheng , Jing Shao , Junjie Yan , Shiming Xiang , Chunhong Pan

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

计算机视觉与模式识别 · 计算机科学 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Weakly supervised object detection (WSOD) aims to tackle the object detection problem using only labeled image categories as supervision. A common approach used in WSOD to deal with the lack of localization information is Multiple Instance…

计算机视觉与模式识别 · 计算机科学 2020-04-24 Luis Felipe Zeni , Claudio Jung

Recently, large-scale pre-trained models have shown their advantages in many tasks. However, due to the huge computational complexity and storage requirements, it is challenging to apply the large-scale model to real scenes. A common…

计算机视觉与模式识别 · 计算机科学 2022-12-27 Deng Li , Aming Wu , Yahong Han , Qi Tian

In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…

计算机视觉与模式识别 · 计算机科学 2024-03-11 H. Keshvarikhojasteh , J. P. W. Pluim , M. Veta

Multiple instance learning (MIL) has become the leading approach for extracting discriminative features from whole slide images (WSIs) in computational pathology. Attention-based MIL methods can identify key patches but tend to overlook…

计算机视觉与模式识别 · 计算机科学 2025-09-30 Lubin Gan , Xiaoman Wu , Jing Zhang , Zhifeng Wang , Linhao Qu , Siying Wu , Xiaoyan Sun

Whole Slide Images (WSIs) are high-resolution digital scans widely used in medical diagnostics. WSI classification is typically approached using Multiple Instance Learning (MIL), where the slide is partitioned into tiles treated as…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Convolutional Neural Networks (CNNs) are prone to overfit small training datasets. We present a novel two-phase pipeline that leverages self-supervised learning and knowledge distillation to improve the generalization ability of CNN models…

计算机视觉与模式识别 · 计算机科学 2020-08-04 Bingchen Zhao , Xin Wen

Deep learning methods usually require a large amount of training data and lack interpretability. In this paper, we propose a novel knowledge distillation and model interpretation framework for medical image classification that jointly…

计算机视觉与模式识别 · 计算机科学 2022-01-13 Thanh Nguyen-Duc , He Zhao , Jianfei Cai , Dinh Phung

Whole slide image (WSI) classification is a critical task in computational pathology. However, the gigapixel-size of such images remains a major challenge for the current state of deep-learning. Current methods rely on multiple-instance…

计算机视觉与模式识别 · 计算机科学 2023-10-04 Etienne Pochet , Rami Maroun , Roger Trullo