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相关论文: CIDGMed: Causal Inference-Driven Medication Recomm…

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Retrieval-Augmented Large Language Models (LLMs), which integrate external knowledge, have shown remarkable performance in medical domains, including clinical diagnosis. However, existing RAG methods often struggle to tailor retrieval…

计算与语言 · 计算机科学 2025-10-16 Jiawei He , Mingyi Jia , Zhihao Jia , Junwen Duan , Yan Song , Jianxin Wang

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

In recent years, there has been a growing interest in using machine learning techniques for the estimation of treatment effects. Most of the best-performing methods rely on representation learning strategies that encourage shared behavior…

机器学习 · 计算机科学 2024-04-19 Roger Pros , Jordi Vitrià

Causal inference methods are widely applied in various decision-making domains such as precision medicine, optimal policy and economics. Central to causal inference is the treatment effect estimation of intervention strategies, such as…

人工智能 · 计算机科学 2021-05-31 Tri Dung Duong , Qian Li , Guandong Xu

Negative controls are increasingly used to evaluate the presence of potential unmeasured confounding in observational studies. Beyond the use of negative controls to detect the presence of residual confounding, proximal causal inference…

统计方法学 · 统计学 2024-06-06 Jiewen Liu , Chan Park , Kendrick Li , Eric J. Tchetgen Tchetgen

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

人工智能 · 计算机科学 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Benefiting from the powerful expressive capability of graphs, graph-based approaches have been popularly applied to handle multi-modal medical data and achieved impressive performance in various biomedical applications. For disease…

机器学习 · 计算机科学 2022-03-14 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yuchen Yang , Yao Zhao

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

机器学习 · 计算机科学 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Molecular property prediction has attracted substantial attention recently. Accurate prediction of drug properties relies heavily on effective molecular representations. The structures of chemical compounds are commonly represented as…

机器学习 · 计算机科学 2025-08-05 Anyin Zhao , Zuquan Chen , Zhengyu Fang , Xiaoge Zhang , Jing Li

Training a deep learning model with artificially generated data can be an alternative when training data are scarce, yet it suffers from poor generalization performance due to a large domain gap. In this paper, we characterize the domain…

计算机视觉与模式识别 · 计算机科学 2023-02-21 Gilhyun Nam , Gyeongjae Choi , Kyungmin Lee

A major limitation of machine learning (ML) prediction models is that they recover associational, rather than causal, predictive relationships between variables. In high-stakes automation applications of ML this is problematic, as the model…

机器学习 · 计算机科学 2025-11-04 Jianqiao Mao , Max A. Little

Medication recommendation is crucial in healthcare, offering effective treatments based on patient's electronic health records (EHR). Previous studies show that integrating more medication-related knowledge improves medication…

人工智能 · 计算机科学 2025-04-28 Xiang Li , Haixu Ma , Guanyong Wu , Shi Mu , Chen Li , Shunpan Liang

Referring medical image segmentation targets delineating lesions indicated by textual descriptions. Aligning visual and textual cues is challenging due to their distinct data properties. Inspired by large-scale pre-trained vision-language…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Yaxiong Chen , Minghong Wei , Zixuan Zheng , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Class incremental medical image segmentation (CIMIS) aims to preserve knowledge of previously learned classes while learning new ones without relying on old-class labels. However, existing methods 1) either adopt one-size-fits-all…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Shengqian Zhu , Chengrong Yu , Qiang Wang , Ying Song , Guangjun Li , Jiafei Wu , Xiaogang Xu , Zhang Yi , Junjie Hu

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

计算与语言 · 计算机科学 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Food recommendation systems serve as pivotal components in the realm of digital lifestyle services, designed to assist users in discovering recipes and food items that resonate with their unique dietary predilections. Typically, multi-modal…

信息检索 · 计算机科学 2025-02-28 Yixin Zhang , Xin Zhou , Qianwen Meng , Fanglin Zhu , Yonghui Xu , Zhiqi Shen , Lizhen Cui

The Granger framework is useful for discovering causal relations in time-varying signals. However, most Granger causality (GC) methods are developed for densely sampled timeseries data. A substantially different setting, particularly common…

机器学习 · 计算机科学 2024-12-19 Minh Nguyen , Gia H. Ngo , Mert R. Sabuncu

Recent researches of large language models(LLM), which is pre-trained on massive general-purpose corpora, have achieved breakthroughs in responding human queries. However, these methods face challenges including limited data insufficiency…

计算与语言 · 计算机科学 2025-01-07 Yiming Zhang , Zheng Chang , Wentao Cai , MengXing Ren , Kang Yuan , Yining Sun , Zenghui Ding

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

计算与语言 · 计算机科学 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Improving generalization and achieving highly predictive, robust machine learning models necessitates learning the underlying causal structure of the variables of interest. A prominent and effective method for this is learning invariant…

机器学习 · 计算机科学 2024-11-12 Jawad Chowdhury , Gabriel Terejanu