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相关论文: Molecule Design by Latent Prompt Transformer

200 篇论文

In this work, we propose to model the interaction between visual and textual features for multi-modal neural machine translation (MMT) through a latent variable model. This latent variable can be seen as a multi-modal stochastic embedding…

计算与语言 · 计算机科学 2019-05-17 Iacer Calixto , Miguel Rios , Wilker Aziz

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

计算与语言 · 计算机科学 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Prompt tuning prepends a soft prompt to the input embeddings or hidden states and only optimizes the prompt to adapt pretrained models (PTMs) to downstream tasks. The previous work manually selects prompt layers which are far from optimal…

计算与语言 · 计算机科学 2023-11-01 Wei Zhu , Ming Tan

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

生物大分子 · 定量生物学 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

We present a novel probabilistic deep learning approach, the 'Stochastic Latent Transformer' (SLT), designed for the efficient reduced-order modelling of stochastic partial differential equations. Stochastically driven flow models are…

机器学习 · 计算机科学 2024-06-21 Ira J. S. Shokar , Rich R. Kerswell , Peter H. Haynes

Text-to-image models have shown remarkable progress in generating high-quality images from user-provided prompts. Despite this, the quality of these images varies due to the models' sensitivity to human language nuances. With advancements…

人工智能 · 计算机科学 2024-06-14 Xinrui Yang , Zhuohan Wang , Anthony Hu

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

生物大分子 · 定量生物学 2024-05-10 Ian Dunn , David Ryan Koes

Large language models achieve state-of-the-art performance but are increasingly costly to fine-tune. Prompt tuning is a parameter-efficient fine-tuning method that addresses parameter-efficiency by learning prompt embeddings, but these…

计算与语言 · 计算机科学 2026-04-14 Zijun Wu , Yongchang Hao , Lili Mou

Large Language Models (LLMs) excel at generating synthetic data, but ensuring its quality and diversity remains challenging. We propose Genetic Prompt, a novel framework that combines genetic algorithms with LLMs to augment synthetic data…

计算与语言 · 计算机科学 2025-09-03 Guangzeng Han , Weisi Liu , Xiaolei Huang

Generative Pre-trained Transformer (GPT) models have achieved remarkable performance on various natural language processing tasks, and have shown great potential as backbones for audio-and-text large language models (LLMs). Previous…

Prompt learning is a new learning paradigm which reformulates downstream tasks as similar pretraining tasks on pretrained models by leveraging textual prompts. Recent works have demonstrated that prompt learning is particularly useful for…

计算与语言 · 计算机科学 2022-10-21 Yue Zhang , Hongliang Fei , Dingcheng Li , Tan Yu , Ping Li

Although generative models hold promise for discovering molecules with optimized desired properties, they often fail to suggest synthesizable molecules that improve upon the known molecules seen in training. We find that a key limitation is…

机器学习 · 计算机科学 2025-01-07 Evan R. Antoniuk , Peggy Li , Nathan Keilbart , Stephen Weitzner , Bhavya Kailkhura , Anna M. Hiszpanski

Pre-trained language models (PLM) have marked a huge leap in neural dialogue modeling. While PLMs are pre-trained on large-scale text corpora, they are usually fine-tuned on scarce dialogue data with specific domain knowledge and dialogue…

计算与语言 · 计算机科学 2021-12-14 Xiaodong Gu , Kang Min Yoo , Sang-Woo Lee

Prompt learning is a new paradigm in the Natural Language Processing (NLP) field which has shown impressive performance on a number of natural language tasks with common benchmarking text datasets in full, few-shot, and zero-shot…

计算与语言 · 计算机科学 2022-05-12 Niall Taylor , Yi Zhang , Dan Joyce , Alejo Nevado-Holgado , Andrey Kormilitzin

In this paper, we evaluate the capability of transformer-based language models in making inferences over uncertain text that includes uncertain rules of reasoning. We cover both Pre-trained Language Models (PLMs) and generative Large…

计算与语言 · 计算机科学 2024-02-12 Aliakbar Nafar , Kristen Brent Venable , Parisa Kordjamshidi

Text entry is an essential task in our day-to-day digital interactions. Numerous intelligent features have been developed to streamline this process, making text entry more effective, efficient, and fluid. These improvements include…

计算与语言 · 计算机科学 2023-10-17 Junxiao Shen , John J. Dudley , Jingyao Zheng , Bill Byrne , Per Ola Kristensson

Large Language Models (LLMs) have demonstrated remarkable capabilities in code generation. However, the quality of the generated code is heavily dependent on the structure and composition of the prompts used. Crafting high-quality prompts…

软件工程 · 计算机科学 2025-04-08 Jinyang Li , Sangwon Hyun , M. Ali Babar

Strategic planning is critical for multi-step reasoning, yet compact Large Language Models (LLMs) often lack the capacity to formulate global strategies, leading to error propagation in long-horizon tasks. Our analysis reveals that LLMs…

计算与语言 · 计算机科学 2026-04-15 Haoyu Zheng , Yun Zhu , Yuqian Yuan , Bo Yuan , Wenqiao Zhang , Siliang Tang , Jun Xiao

Training generative models that capture rich semantics of the data and interpreting the latent representations encoded by such models are very important problems in un-/self-supervised learning. In this work, we provide a simple algorithm…

机器学习 · 计算机科学 2024-09-02 Samuel C. Hoffman , Payel Das , Karthikeyan Shanmugam , Kahini Wadhawan , Prasanna Sattigeri

Pre-trained vision-language models (VLMs) have shown impressive performance on various downstream tasks by utilizing knowledge learned from large data. In general, the performance of VLMs on target tasks can be further improved by prompt…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Eulrang Cho , Jooyeon Kim , Hyunwoo J. Kim