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相关论文: Predicting O-GlcNAcylation Sites in Mammalian Prot…

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Neural networks are trained by minimizing a loss function that defines the discrepancy between the predicted model output and the target value. The selection of the loss function is crucial to achieve task-specific behaviour and highly…

计算机视觉与模式识别 · 计算机科学 2024-04-22 Shakhnaz Akhmedova , Nils Körber

We propose SEARNN, a novel training algorithm for recurrent neural networks (RNNs) inspired by the "learning to search" (L2S) approach to structured prediction. RNNs have been widely successful in structured prediction applications such as…

机器学习 · 计算机科学 2018-03-06 Rémi Leblond , Jean-Baptiste Alayrac , Anton Osokin , Simon Lacoste-Julien

Many applications of machine learning require a model to make accurate pre-dictions on test examples that are distributionally different from training ones, while task-specific labels are scarce during training. An effective approach to…

机器学习 · 计算机科学 2020-02-20 Weihua Hu , Bowen Liu , Joseph Gomes , Marinka Zitnik , Percy Liang , Vijay Pande , Jure Leskovec

Biological agents are known to learn many different tasks over the course of their lives, and to be able to revisit previous tasks and behaviors with little to no loss in performance. In contrast, artificial agents are prone to…

机器学习 · 计算机科学 2021-12-16 Ta-Chu Kao , Kristopher T. Jensen , Gido M. van de Ven , Alberto Bernacchia , Guillaume Hennequin

The likelihood of O-GlcNAc glycosylation in human proteins is predicted using the ridge regression estimated linear probability model (LPM). To achieve this, sequences from three similar post-translational modifications (PTMs) of proteins…

定量方法 · 定量生物学 2019-07-09 Rajaram Gana , Sona Vasudevan

Loss function learning is a new meta-learning paradigm that aims to automate the essential task of designing a loss function for a machine learning model. Existing techniques for loss function learning have shown promising results, often…

机器学习 · 计算机科学 2025-10-14 Christian Raymond , Qi Chen , Bing Xue , Mengjie Zhang

Deep neural networks, albeit their great success on feature learning in various computer vision tasks, are usually considered as impractical for online visual tracking because they require very long training time and a large number of…

计算机视觉与模式识别 · 计算机科学 2016-05-04 Hanxi Li , Yi Li , Fatih Porikli

Computational drug discovery provides an efficient tool helping large scale lead molecules screening. One of the major tasks of lead discovery is identifying molecules with promising binding affinities towards a target, a protein in…

生物物理 · 物理学 2019-09-18 Liangzhen Zheng , Jingrong Fan , Yuguang Mu

With the development of next generation sequencing techniques, it is fast and cheap to determine protein sequences but relatively slow and expensive to extract useful information from protein sequences because of limitations of traditional…

定量方法 · 定量生物学 2017-10-20 Renzhi Cao , Colton Freitas , Leong Chan , Miao Sun , Haiqing Jiang , Zhangxin Chen

Graph Neural Networks (GNNs), especially message-passing-based models, have become prominent in top-k recommendation tasks, outperforming matrix factorization models due to their ability to efficiently aggregate information from a broader…

信息检索 · 计算机科学 2024-07-12 Yannis Karmim , Elias Ramzi , Raphaël Fournier-S'niehotta , Nicolas Thome

Convolutional Neural Networks (CNNs) have shown to be powerful medical image segmentation models. In this study, we address some of the main unresolved issues regarding these models. Specifically, training of these models on small medical…

计算机视觉与模式识别 · 计算机科学 2022-12-06 Davood Karimi , Ali Gholipour

As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

定量方法 · 定量生物学 2017-01-31 Xueliang Liu

Transfer learning is widely used for training deep neural networks (DNN) for building a powerful representation. Even after the pre-trained model is adapted for the target task, the representation performance of the feature extractor is…

机器学习 · 计算机科学 2023-08-22 Seunghee Koh , Hyounguk Shon , Janghyeon Lee , Hyeong Gwon Hong , Junmo Kim

The objective of this work is to improve the accuracy of building demand forecasting. This is a more challenging task than grid level forecasting. For the said purpose, we develop a new technique called recurrent transform learning (RTL).…

机器学习 · 计算机科学 2019-12-12 Megha Gupta , Angshul Majumdar

Protein function prediction is a crucial task in bioinformatics, with significant implications for understanding biological processes and disease mechanisms. While the relationship between sequence and function has been extensively…

定量方法 · 定量生物学 2024-09-04 Shania Mitra , Lei Huang , Manolis Kellis

The LASSO-Clip-EN (LCEN) algorithm was previously introduced for nonlinear, interpretable feature selection and machine learning. However, its design and use was limited to regression tasks. In this work, we create a modified version of the…

机器学习 · 计算机科学 2026-04-24 Pedro Seber , Richard D. Braatz

Algorithmic image-based diagnosis and prognosis of neurodegenerative diseases on longitudinal data has drawn great interest from computer vision researchers. The current state-of-the-art models for many image classification tasks are based…

计算机视觉与模式识别 · 计算机科学 2017-09-04 Jie Zhang , Qingyang Li , Richard J. Caselli , Jieping Ye , Yalin Wang

With the advent of next-generation surveys and the expectation of discovering huge numbers of strong gravitational lens systems, much effort is being invested into developing automated procedures for handling the data. The several orders of…

星系天体物理 · 物理学 2021-02-17 Jacob Maresca , Simon Dye , Nan Li

Grasping objects is one of the most important abilities that a robot needs to master in order to interact with its environment. Current state-of-the-art methods rely on deep neural networks trained to jointly predict a graspability score…

机器人学 · 计算机科学 2021-04-01 Amaury Depierre , Emmanuel Dellandréa , Liming Chen

Convolutional Neural Networks (CNNs) are widely used for image classification in a variety of fields, including medical imaging. While most studies deploy cross-entropy as the loss function in such tasks, a growing number of approaches have…

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