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A common problem in bioinformatics is related to identifying gene regulatory regions marked by relatively high frequencies of motifs, or deoxyribonucleic acid sequences that often code for transcription and enhancer proteins. Predicting…

基因组学 · 定量生物学 2021-01-22 Ethan Jacob Moyer , Anup Das

Conventionally, pairwise relationships between nodes are considered to be the fundamental building blocks of complex networks. However, over the last decade the overabundance of certain sub-network patterns, so called motifs, has attracted…

物理与社会 · 物理学 2015-01-28 Marco Winkler , Joerg Reichardt

Networks are ubiquitous structure that describes complex relationships between different entities in the real world. As a critical component of prediction task over nodes in networks, learning the feature representation of nodes has become…

机器学习 · 计算机科学 2018-09-10 Hansheng Xue , Jiajie Peng , Xuequn Shang

Characterizing motif (i.e., locally connected subgraph patterns) statistics is important for understanding complex networks such as online social networks and communication networks. Previous work made the strong assumption that the graph…

社会与信息网络 · 计算机科学 2015-02-25 Pinghui Wang , John C. S. Lui , Don Towsley

Relational data mining is becoming ubiquitous in many fields of study. It offers insights into behaviour of complex, real-world systems which cannot be modeled directly using propositional learning. We propose Symbolic Graph Embedding…

机器学习 · 计算机科学 2019-10-30 Blaz Škrlj , Jan Kralj , Nada Lavrač

We consider feature representation learning problem of molecular graphs. Graph Neural Networks have been widely used in feature representation learning of molecular graphs. However, most existing methods deal with molecular graphs…

机器学习 · 计算机科学 2022-06-08 Zhaoning Yu , Hongyang Gao

Sequential pattern mining (SPM) with gap constraints (or repetitive SPM or tandem repeat discovery in bioinformatics) can find frequent repetitive subsequences satisfying gap constraints, which are called positive sequential patterns with…

数据库 · 计算机科学 2025-02-11 Yan Li , Zhulin Wang , Jing Liu , Lei Guo , Philippe Fournier-Viger , Youxi Wu , Xindong Wu

Deep learning methods for graphs achieve remarkable performance on many node-level and graph-level prediction tasks. However, despite the proliferation of the methods and their success, prevailing Graph Neural Networks (GNNs) neglect…

机器学习 · 计算机科学 2020-11-10 Emily Alsentzer , Samuel G. Finlayson , Michelle M. Li , Marinka Zitnik

Pattern counting in graphs is fundamental to network science tasks, and there are many scalable methods for approximating counts of small patterns, often called motifs, in large graphs. However, modern graph datasets now contain richer…

社会与信息网络 · 计算机科学 2018-10-03 Paul Liu , Austin Benson , Moses Charikar

Link prediction is one of the central problems in graph mining. However, recent studies highlight the importance of higher-order network analysis, where complex structures called motifs are the first-class citizens. We first show that…

Identifying super-spreaders can be framed as a subtask of the influence maximisation problem. It seeks to pinpoint agents within a network that, if selected as single diffusion seeds, disseminate information most effectively. Multilayer…

社会与信息网络 · 计算机科学 2025-10-27 Michał Czuba , Mateusz Stolarski , Adam Piróg , Piotr Bielak , Piotr Bródka

Graph mining applications, such as subgraph pattern matching and mining, are widely used in real-world domains such as bioinformatics, social network analysis, and computer vision. Such applications are considered a new class of…

硬件体系结构 · 计算机科学 2023-06-21 Jiya Su , Peng Jiang , Rujia Wang

Network analysis has played a key role in knowledge discovery and data mining. In many real-world applications in recent years, we are interested in mining multilayer networks, where we have a number of edge sets called layers, which encode…

社会与信息网络 · 计算机科学 2022-11-08 Yasushi Kawase , Atsushi Miyauchi , Hanna Sumita

Frequent Subgraph Mining (FSM) is the key task in many graph mining and machine learning applications. Numerous systems have been proposed for FSM in the past decade. Although these systems show good performance for small patterns (with no…

数据库 · 计算机科学 2021-02-09 Peng Jiang , Rujia Wang , Bo Wu

Motif discovery is one of the most challenging problems in bioinformatics today. DNA sequence motifs are becoming increasingly important in analysis of gene regulation. Motifs are short, recurring patterns in DNA that have a biological…

分布式、并行与集群计算 · 计算机科学 2014-05-05 Umang Vipul

While Graph Neural Networks (GNNs) are powerful models for learning representations on graphs, most state-of-the-art models do not have significant accuracy gain beyond two to three layers. Deep GNNs fundamentally need to address: 1).…

Frequent Subgraph Mining (FSM) is the process of identifying common subgraph patterns that surpass a predefined frequency threshold. While FSM is widely applicable in fields like bioinformatics, chemical analysis, and social network anomaly…

数据库 · 计算机科学 2024-04-03 Akshit Sharma , Sam Reinher , Dinesh Mehta , Bo Wu

We present a novel graph embedding space (i.e., a set of measures on graphs) for performing statistical analyses of networks. Key improvements over existing approaches include discovery of "motif-hubs" (multiple overlapping significant…

无序系统与神经网络 · 物理学 2007-05-23 Etay Ziv , Robin Koytcheff , Manuel Middendorf , Chris Wiggins

The detection of triadic subgraph motifs is a common methodology in complex-networks research. The procedure usually applied in order to detect motifs evaluates whether a certain subgraph pattern is overrepresented in a network as a whole.…

社会与信息网络 · 计算机科学 2015-09-14 Marco Winkler

We address the problem of computing the distribution of induced connected subgraphs, aka \emph{graphlets} or \emph{motifs}, in large graphs. The current state-of-the-art algorithms estimate the motif counts via uniform sampling, by…

数据结构与算法 · 计算机科学 2021-07-20 Marco Bressan , Stefano Leucci , Alessandro Panconesi