相关论文: UniCell: Universal Cell Nucleus Classification via…

An automated segmentation and classification of nuclei is an essential task in digital pathology. The current deep learning-based approaches require a vast amount of annotated datasets by pathologists. However, the existing datasets are…

Molecular representation learning is fundamental for many drug related applications. Most existing molecular pre-training models are limited in using single molecular modality, either SMILES or graph representation. To effectively leverage…

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Over one in three people are affected by neurodegenerative disorders. Neural stem cells, which are multipotent regenerative cells with the potential to differentiate into any of the neural cell types, have immense therapeutic potential for…

Machine learning and deep learning (ML/DL) have been extensively applied in malware detection, and some existing methods demonstrate robust performance. However, several issues persist in the field of malware detection: (1) Existing work…

Image classification is a well-studied task in computer vision, and yet it remains challenging under high-uncertainty conditions, such as when input images are corrupted or training data are limited. Conventional classification approaches…

Driven by advancements in deep learning, computer-aided diagnoses have made remarkable progress. However, outside controlled laboratory settings, algorithms may encounter several challenges. In the medical domain, these difficulties often…

Deep learning has shown state-of-art classification performance on datasets such as ImageNet, which contain a single object in each image. However, multi-object classification is far more challenging. We present a unified framework which…

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Characterizing uncertainty is a common issue in nuclear measurement and has important implications for reliable physical discovery. Traditional methods are either insufficient to cope with the heterogeneous nature of uncertainty or…

Cell line authentication plays a crucial role in the biomedical field, ensuring researchers work with accurately identified cells. Supervised deep learning has made remarkable strides in cell line identification by studying cell…

Recently, deep learning (DL) has been emerging as a promising approach for channel estimation and signal detection in wireless communications. The majority of the existing studies investigating the use of DL techniques in this domain focus…

Molecular representation learning plays a crucial role in advancing applications such as drug discovery and material design. Existing work leverages 2D and 3D modalities of molecular information for pre-training, aiming to capture…

Accurate prediction of molecular properties is crucial in drug discovery. Traditional methods often overlook that real-world molecules typically exhibit multiple property labels with complex correlations. To this end, we propose a novel…

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Continual learning offers…

Knowledge of molecular subtypes of gliomas can provide valuable information for tailored therapies. This study aimed to investigate the use of deep convolutional neural networks (DCNNs) for noninvasive glioma subtyping with radiological…

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Clear cell renal cell carcinoma (ccRCC) is one of the most common forms of intratumoral heterogeneity in the study of renal cancer. ccRCC originates from the epithelial lining of proximal convoluted renal tubules. These cells undergo…