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Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial…

流体动力学 · 物理学 2020-05-20 Mohammed Nasir Uddin , M. Monir Uddin , Md. Monjarul Alam

Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…

图像与视频处理 · 电气工程与系统科学 2025-08-28 Utsav Ratna Tuladhar , Richard Simon , Doran Mix , Michael Richards

Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…

医学物理 · 物理学 2025-03-04 Doyeol , Ahn

An abdominal aortic aneurysm (AAA) is a focal dilation of the aorta that, if not treated, tends to grow and may rupture. A significant unmet need in the assessment of AAA disease, for the diagnosis, prognosis and follow-up, is the…

计算机视觉与模式识别 · 计算机科学 2019-03-05 Karen López-Linares , Inmaculada García , Ainhoa García-Familiar , Iván Macía , Miguel A. González Ballester

Coronary anatomy governs local haemodynamics associated with atherosclerotic development, progression and ultimately adverse clinical outcomes. However, lack of large sample size studies and methods to link adverse haemodynamics to…

医学物理 · 物理学 2024-01-24 R. Gharleghi , M. Zhang , C. Shen , M. Webster , C. Ellis , S. Beier

Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…

其他定量生物学 · 定量生物学 2025-05-22 Reza Bozorgpour , Pilwan Kim

Vascular access, such as arteriovenous grafts, is crucial for patients undergoing haemodialysis as part of kidney replacement therapy. One of the primary causes of arteriovenous graft failure and loss of patency is disordered blood flow, as…

组织与器官 · 定量生物学 2025-08-11 Guanqi Wang , Thomas Abadie , Ivan Wall , Patricia Pérez Esteban

Characterization of medium-range order in amorphous materials and its relation to short-range order is discussed. A new topological approach is presented here to extract a hierarchical structure of amorphous materials, which is robust…

软凝聚态物质 · 物理学 2015-02-27 Takenobu Nakamura , Yasuaki Hiraoka , Akihiko Hirata , Emerson G. Escolar , Yasumasa Nishiura

New representations of tree-structured data objects, using ideas from topological data analysis, enable improved statistical analyses of a population of brain artery trees. A number of representations of each data tree arise from…

应用统计 · 统计学 2014-11-26 Paul Bendich , J. S. Marron , Ezra Miller , Alex Pieloch , Sean Skwerer

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…

计算工程、金融与科学 · 计算机科学 2020-03-16 Shanlin Qin , Rongliang Chen , Bokai Wu , Jia Liu , Wen-Shin Shiu , Zhengzheng Yan , Xiao-Chuan Cai

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

计算机视觉与模式识别 · 计算机科学 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

计算机视觉与模式识别 · 计算机科学 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

Aortic root dilation and propensity to dissection are typical manifestations of the Marfan Syndrome (MS), a genetic defect leading to the degeneration of the elastic fibres. Dilation affects the structure of the flow and, in turn, altered…

流体动力学 · 物理学 2014-11-03 Giorgio Querzoli , Stefania Fortini , Stefania Espa , Martina Costantini , Francesca Sorgini

Purpose. It has been reported clinically that rupture or dissections in thoracic aortic aneurysms (TAA) often occur due to hypertension which may be modelled with sudden increase of peripheral resistance, inducing acute changes of blood…

We propose a deep learning-based technique for detection and quantification of abdominal aortic aneurysms (AAAs). The condition, which leads to more than 10,000 deaths per year in the United States, is asymptomatic, often detected…

In CT angiography, the accurate segmentation of abdominal aortic aneurysms (AAAs) is difficult due to large anatomical variability, low-contrast vessel boundaries, and the close proximity of organs whose intensities resemble vascular…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Osamah Sufyan , Martin Brückmann , Ralph Wickenhöfer , Babette Dellen , Uwe Jaekel

Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their…

流体动力学 · 物理学 2023-08-17 Aurèle Goetz , Pablo Jeken Rico , Yves Chau , Jacques Sédat , Aurélien Larcher , Elie Hachem

Bileaflet mechanical heart valves have one of the most successful valve designs for more than 30 years. These valves are often used for aortic valve replacement, where the geometry of the aortic root sinuses may vary due to valvular disease…

流体动力学 · 物理学 2018-03-12 Fardin Khalili , Peshala P. T. Gamage , Hansen A. Mansy

In this paper we present an efficient algorithm for the segmentation of the inner and outer boundary of thoratic and abdominal aortic aneurysms (TAA & AAA) in computed tomography angiography (CTA) acquisitions. The aneurysm segmentation…

计算机视觉与模式识别 · 计算机科学 2016-02-10 Jing Lu , Jan Egger , Andreas Wimmer , Stefan Großkopf , Bernd Freisleben

Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart…

医学物理 · 物理学 2019-11-14 Ahmed Darwish , Giuseppe Di Labbio , Wael Saleh , Othman Smadi , Lyes Kadem