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Rupture of intracranial aneurysms results in severe subarachnoidal hemorrhage, which is associated with high morbidity and mortality. Neurointerventional occlusion of the aneurysm through coiling has evolved to a therapeutical standard. The…

计算工程、金融与科学 · 计算机科学 2024-03-12 Julian Schwarting , Fabian Holzberger , Markus Muhr , Martin Renz , Tobias Boeckh-Behrens , Barbara Wohlmuth , Jan Kirschke

Enodvascular coils treat intracranial aneurysms (IAs) by causing them to occlude by thrombosis. Ideally, coiled IAs eventually occlude in the long-term. However, 20.8% are found incompletely occluded at treatment follow-up. Computer…

Predicting the long-term success of endovascular interventions in the clinical management of cerebral aneurysms requires detailed insight into the patient-specific physiological conditions. In this work, we not only propose numerical…

Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…

计算工程、金融与科学 · 计算机科学 2026-05-06 Fabian Holzberger , Struan Hume , Markus Muhr , Malebogo Ngoepe , Barbara Wohlmuth

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Intracranial aneurysms are the leading cause of hemorrhagic stroke. One of the established treatment approaches is the embolization induced by coil insertion. However, the prediction of treatment and subsequent changed flow characteristics…

数值分析 · 数学 2026-05-20 Medeea Horvat , Stephan B. Lunowa , Dmytro Sytnyk , Barbara Wohlmuth

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

The two most important aneurysm types are cerebral aneurysms (CA) and abdominal aortic aneurysms (AAA), accounting together for over 80\% of all fatal aneurysm incidences. To minimise aneurysm related deaths, clinicians require various…

A commonly adopted approach to carry out detection tasks in medical imaging is to rely on an initial segmentation. However, this approach strongly depends on voxel-wise annotations which are repetitive and time-consuming to draw for medical…

We hereby present a full synthetic model, able to mimic the various constituents of the cerebral vascular tree, including the cerebral arteries, bifurcations and intracranial aneurysms. This model intends to provide a substantial dataset of…

计算机视觉与模式识别 · 计算机科学 2024-11-06 Rafic Nader , Florent Autrusseau , Vincent L'Allinec , Romain Bourcier

Cerebral aneurysms affect three to five percent of the population, and rupture remains a major cause of stroke-related death and disability. Current therapies, surgical clipping, endovascular coiling, and flow diversion, have improved…

组织与器官 · 定量生物学 2025-09-25 Duong Le

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

Currently, it is challenging to investigate aneurismal hemodynamics based on current in-vivo data such as Magnetic Resonance Imaging or Computed Tomography due to the limitations in both spatial and temporal resolutions. In this work, we…

流体动力学 · 物理学 2024-10-17 Thien-Tam Nguyen , Davina Kasperski , Phat Kim Huynh , Trung Quoc Le , Trung Bao Le

The exact shape of intracranial aneurysms is critical in medical diagnosis and surgical planning. While voxel-based deep learning frameworks have been proposed for this segmentation task, their performance remains limited. In this study, we…

图像与视频处理 · 电气工程与系统科学 2021-07-06 Xi Yang , Ding Xia , Taichi Kin , Takeo Igarashi

Computational fluid dynamics is intensively used to deepen the understanding of aneurysm growth and rupture in the attempt to support physicians during therapy planning. Numerous studies have assumed fully-rigid vessel walls in their…

流体动力学 · 物理学 2023-08-17 Aurèle Goetz , Pablo Jeken Rico , Yves Chau , Jacques Sédat , Aurélien Larcher , Elie Hachem

Endoluminal reconstruction using flow diverters represents a novel paradigm for the minimally invasive treatment of intracranial aneurysms. The configuration assumed by these very dense braided stents once deployed within the parent vessel…

计算工程、金融与科学 · 计算机科学 2023-01-23 Beatrice Bisighini , Miquel Aguirre , Marco Evangelos Biancolini , Federica Trovalusci , David Perrin , Stephane Avril , Baptiste Pierrat

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

Endovascular aneurysm repair (EVAR) is a current alternative treatment for thoracic and abdominal aortic aneurysms, but is still sometimes compromised by possible complications such as device migration or endoleaks. In order to assist…

医学物理 · 物理学 2019-02-05 V. Acosta Santamaría , G. Daniel , D. Perrin , J. Albertini , E. Rosset , S. Avril

Background:Subarachnoid hemorrhage caused by ruptured cerebral aneurysm often leads to fatal consequences.However,if the aneurysm can be found and treated during asymptomatic periods,the probability of rupture can be greatly reduced.At…

图像与视频处理 · 电气工程与系统科学 2021-10-27 Chen Geng , Meng Chen , Ruoyu Di , Dongdong Wang , Liqin Yang , Wei Xia , Yuxin Li , Daoying Geng

This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…

定量方法 · 定量生物学 2026-02-17 Reza Bozorgpour , Jacob R. Rammer
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