相关论文: Spatial Transcriptomics Analysis of Zero-shot Gene…

The need to address the scarcity of task-specific annotated data has resulted in concerted efforts in recent years for specific settings such as zero-shot learning (ZSL) and domain generalization (DG), to separately address the issues of…

Vision-Language Models (VLMs) excel at zero-shot inference but often degrade under test-time domain shifts. For this reason, episodic test-time adaptation strategies have recently emerged as powerful techniques for adapting VLMs to a single…

Human and animal tissues consist of heterogeneous cell types that organize and interact in highly structured manners. Bulk and single-cell sequencing technologies remove cells from their original microenvironments, resulting in a loss of…

Identifying genes that display spatial patterns is critical to investigating expression interactions within a spatial context and further dissecting biological understanding of complex mechanistic functionality. Despite the increase in…

Zero-shot learning aims at recognizing unseen classes (no training example) with knowledge transferred from seen classes. This is typically achieved by exploiting a semantic feature space shared by both seen and unseen classes, i.e.,…

This paper aims to predict gene expression from a histology slide image precisely. Such a slide image has a large resolution and sparsely distributed textures. These obstruct extracting and interpreting discriminative features from the…

The existing Zero-Shot learning (ZSL) methods may suffer from the vague class attributes that are highly overlapped for different classes. Unlike these methods that ignore the discrimination among classes, in this paper, we propose to…

Spatial transcriptomics (ST) technologies can be used to align transcriptomes with histopathological morphology, presenting exciting new opportunities for biomolecular discovery. Using ST data, we construct a novel framework, GeneFlow, to…

Zero-shot learning (ZSL) aims to recognize unseen image categories by learning an embedding space between image and semantic representations. For years, among existing works, it has been the center task to learn the proper mapping matrices…

Zero-shot learning relies on semantic class representations such as hand-engineered attributes or learned embeddings to predict classes without any labeled examples. We propose to learn class representations by embedding nodes from common…

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

We propose a method to infer domain-specific models such as classifiers for unseen domains, from which no data are given in the training phase, without domain semantic descriptors. When training and test distributions are different,…

Spatial transcriptomics provides an unprecedented perspective for deciphering tissue spatial heterogeneity. However, high-resolution spatial transcriptomic technology remains constrained by limited gene coverage, technical complexity, and…

Spatial transcriptomics (ST) enables spot-level in situ expression profiling, but its high cost and limited throughput motivate predicting expression directly from HE-stained histology. Recent advances explore using score- or flow-based…

Zero-shot learning (ZSL) is to handle the prediction of those unseen classes that have no labeled training data. Recently, generative methods like Generative Adversarial Networks (GANs) are being widely investigated for ZSL due to their…

Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…

Spatial transcriptomics enables genome-wide expression analysis within native tissue context, yet identifying spatial domains remains challenging due to complex gene-spatial interactions. Existing methods typically process spatial and…

Zero shot learning in Image Classification refers to the setting where images from some novel classes are absent in the training data but other information such as natural language descriptions or attribute vectors of the classes are…

In image recognition, there are many cases where training samples cannot cover all target classes. Zero-shot learning (ZSL) utilizes the class semantic information to classify samples of the unseen categories that have no corresponding…

Semantic segmentation, which aims to acquire a detailed understanding of images, is an essential issue in computer vision. However, in practical scenarios, new categories that are different from the categories in training usually appear.…