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Transcranial focused ultrasound (tFUS) offers noninvasive access to deep brain circuits but remains limited by skull-induced phase aberration, acoustic impedance mismatch, and poor volumetric control of intracranial pressure fields.…

We report 3D-printed acoustic holographic lenses for the formation of ultrasonic fields of complex spatial distribution inside the skull. Using holographic lenses, we experimentally, numerically and theoretically produce acoustic beams…

Acoustic holography in the megahertz frequency range can impact numerous applications, including manufacturing, non-destructive testing, and transcranial ultrasound. However, designing lens topologies for complex acoustic holograms in the…

应用物理 · 物理学 2025-08-26 Pradosh Pritam Dash , Costas D. Arvanitis

Acoustic holography provides a practical means of flexibly controlling acoustic wavefronts. However, high-fidelity shaping of acoustic fields remains constrained by the numerical-physical gap inherent in conventional phase-only designs.…

系统与控制 · 电气工程与系统科学 2026-03-25 Moon Hwan Lee , Mohd. Afzal Khan , Akm Ashiquzzaman , Eunbin Lee , Jonghun Lee , Euiheon Chung , Hyuk-Sang Kwon , Jae Youn Hwang

The correction of the aberration of transcranial focused ultrasounds is a relevant issue for enhancing various non-invasive medical treatments. Emission through multi-element phased arrays has been the most widely accepted method to reduce…

医学物理 · 物理学 2018-05-28 Marcelino Ferri , JM Bravo , Javier Redondo , JV Sánchez-Pérez

The correction of transcranial focused ultrasound aberrations is a relevant topic for enhancing various non-invasive medical treatments. Nowadays, the most widely accepted method to improve focusing is the emission through multi-element…

Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Vinkle Srivastav , Juliette Puel , Jonathan Vappou , Elijah Van Houten , Paolo Cabras , Nicolas Padoy

Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…

In therapeutic focused ultrasound (FUS), such as thermal ablation and hyperthermia, effective acousto-thermal manipulation requires precise targeting of complex geometries, sound wave propagation through irregular structures and selective…

应用物理 · 物理学 2024-09-04 Ceren Cengiz , Zekeriya Ender Eger , Pinar Acar , Wynn Legon , Shima Shahab

Ultrasound, alone or in concert with circulating microbubble contrast agents, has emerged as a promising modality for therapy and imaging of brain diseases. While this has become possible due to advancements in aberration correction…

信号处理 · 电气工程与系统科学 2020-01-08 Scott Schoen , Costas D. Arvanitis

Optical geometric-phase metasurface provides a robust and efficient means for light control by simply manipulating the spatial orientations of the in-plane anisotropic meta-atoms, where polarization conversion plays a vital role. However,…

经典物理 · 物理学 2022-06-08 Bingyi Liu , Qunshuo Wei , Zhaoxian Su , Yongtian Wang , Lingling Huang

Ultrasound vortices have rapidly expanded their applications to areas like particle trapping, contactless manipulation, acoustic communications. In ultrasonic imaging and therapy involving bone tissues, these vortex beams offer intriguing…

医学物理 · 物理学 2026-01-21 Zhongtao Hu

In recent years high-resolution 3D printing has enabled a diverse range of new, low-cost, methods for ultrasonic wave-front shaping. Acoustic holograms, particularly, allow for the generation of arbitrary, diffraction limited, acoustic…

医学物理 · 物理学 2022-09-07 Michael D. Brown , Ben T. Cox , Bradley E. Treeby

Advances in additive manufacturing have enabled the realisation of inexpensive, scalable, diffractive acoustic lenses that can be used to generate complex acoustic fields via phase and/or amplitude modulation. However, the design of these…

声音 · 计算机科学 2023-05-08 Antonio Stanziola , Ben T. Cox , Bradley E. Treeby , Michael D. Brown

Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…

医学物理 · 物理学 2024-10-29 Kasra Naftchi-Ardebili , Karanpartap Singh , Gerald R. Popelka , Kim Butts Pauly

Acoustic impedance mismatches between soft tissues and bones are known to result in strong aberrations in optoacoustic and ultrasound images. Of particular importance are the severe distortions introduced by the human skull, impeding…

医学物理 · 物理学 2021-08-10 Xose Luis Dean-Ben , Daniel Razansky

A novel approach to improving the performances of confocal scanning imaging is proposed. We experimentally demonstrate its feasibility using acoustic waves. It relies on a new way to encode spatial information using the temporal dimension.…

Optical and acoustic metasurfaces are two-dimensional arrays of subwavelength elements that locally modulate or phase shift incident waves. Acoustoplasmonic metasurfaces combine the physics of light and sound, producing acoustic wavefronts…

应用物理 · 物理学 2025-04-11 Julia E. Holland , Nicholas Boechler , Lisa V. Poulikakos

Low-intensity transcranial focused ultrasound (tFUS) is rapidly emerging as a transformative non-invasive brain stimulation (NIBS) modality characterized by high spatial resolution and ability to target deep brain circuits. Unlike…

神经元与认知 · 定量生物学 2026-04-02 William J. Tyler

Robot-assisted minimally invasive surgery benefits from enhancing dynamic scene reconstruction, as it improves surgical outcomes. While Neural Radiance Fields (NeRF) have been effective in scene reconstruction, their slow inference speeds…

计算机视觉与模式识别 · 计算机科学 2024-09-11 Haoyu Zhao , Xingyue Zhao , Lingting Zhu , Weixi Zheng , Yongchao Xu
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