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Color centers in diamond nanocrystals are a new class of fluorescence markers that attract significant interest due to matchless brightness, photostability and biochemical inertness. Fluorescing diamond nanocrystals containing defects can…

生物大分子 · 定量生物学 2009-11-13 M. Boersch , R. Reuter , G. Balasubramanian , R. Erdmann , F. Jelezko , J. Wrachtrup

Nanodiamonds containing nitrogen-vacancy (NV) centers offer a versatile platform for sensing applications spanning from nanomagnetism to in-vivo monitoring of cellular processes. In many cases, however, weak optical signals and poor…

量子物理 · 物理学 2018-04-30 David A. Hopper , Richard R. Grote , Samuel M. Parks , Lee C. Bassett

We report on sensing stability of nanodiamond (ND) quantum sensors in various pH aqueous buffer solutions for the two detection schemes of quantum decoherence spectroscopy and thermometry. The electron spin properties of single…

介观与纳米尺度物理 · 物理学 2019-10-17 Masazumi Fujiwara , Ryuta Tsukahara , Yoshihiko Sera , Hiroshi Yukawa , Yoshinobu Baba , Shinichi Shikata , Hideki Hashimoto

A key limitation of electron paramagnetic resonance (EPR), an established and powerful tool for studying atomic-scale biomolecular structure and dynamics is its poor sensitivity, samples containing in excess of 10^12 labeled biomolecules…

The fluorescent nitrogen-vacancy (NV) defect in diamond has remarkable photophysical properties, including high photostability, which allows stable fluorescence emission for hours; as a result, there has been much interest in using…

Nitrogen-vacancy (NV) centers in diamond have emerged as valuable tools for sensing and polarizing spins. Motivated by potential applications in chemistry, biology, and medicine, we show that NV-based sensors are capable of detecting single…

量子物理 · 物理学 2016-03-10 M. Bruderer , P. Fernández-Acebal , R. Aurich , M. B. Plenio

Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…

光学 · 物理学 2022-02-28 Yaofei Chen , Qianyu Lin , Hongda Cheng , Yingying Ye , Gui-Shi Liu , Lei Chen , Yunhan Luo , Zhe Chen

The investigation of biomolecular interactions at the single-molecule level has emerged as a pivotal research area in life science, particularly through optical, mechanical, and electrochemical approaches. Spins existing widely in…

A simple and convenient design enables real-time three-dimensional position tracking of nitrogen-vacancy (NV) centers in diamond. The system consists entirely of commercially available components (a single photon counter, a high-speed…

仪器与探测器 · 物理学 2018-03-14 Kiho Kim , Jiwon Yun , Donghyuck Lee , Dohun Kim

Probing electrical and magnetic properties in aqueous environments remains a frontier challenge in nanoscale sensing. Our inability to do so with quantitative accuracy imposes severe limitations, for example, on our understanding of the…

Due to its superior coherent and optical properties at room temperature, the nitrogen-vacancy (N-V ) center in diamond has become a promising quantum probe for nanoscale quantum sensing. However, the application of N-V containing…

The Nitrogen-Vacancy (NV) defect in diamond is a unique quantum system that offers precision sensing of nanoscale physical quantities beyond the current state-of-the-art. Here we present a method to controllably encode the interactions in…

A key challenge for neuroscience is noninvasive, label-free sensing of action potential (AP) dynamics in whole organisms with single-neuron resolution. Here, we present a new approach to this problem: using nitrogen-vacancy (NV) quantum…

量子物理 · 物理学 2016-12-26 J. F. Barry , M. J. Turner , J. M. Schloss , D. R. Glenn , Y. Song , M. D. Lukin , H. Park , R. L. Walsworth

Nitrogen-vacancy (NV) centers in nanodiamonds are excellent nanoscale sensors for measuring parameters such as temperature, magnetic field, and viscosity in complex fluidic environments, including living cells. However, the rapid motion of…

Nuclear magnetic resonance (NMR) imaging with shallow nitrogen-vacancy (NV) centers in diamond offers an exciting route toward sensitive and localized chemical characterization at the nanoscale. Remarkable progress has been made to combat…

The nitrogen-vacancy (NV) defect center in diamond has demonstrated great capability for nanoscale magnetic sensing and imaging for both static and periodically modulated target fields. However, it remains a challenge to detect and image…

介观与纳米尺度物理 · 物理学 2014-09-19 Lan Luan , Michael S. Grinolds , Sungkun Hong , Patrick Maletinsky , Ronald L. Walsworth , Amir Yacoby

High biocompatibility, variable size ranging from ~ 5 nm, stable luminescence from its color centers and simple carbon chemistry for biomolecule grafting make nanodiamond (ND) particles an attractive alternative to molecular dyes for…

Nitrogen vacancy (NV) centers in diamond are promising elemental blocks for quantum optics [1, 2], spin-based quantum information processing [3, 4], and high-resolution sensing [5-13]. Yet, fully exploiting these capabilities of single NV…

We present a protocol that detects molecular conformational changes with two nitroxide electron-spin labels and a nitrogen-vacancy (NV) center in diamond. More specifically, we demonstrate that the NV can detect energy shifts induced by the…

量子物理 · 物理学 2022-12-21 C. Munuera-Javaloy , R. Puebla , B. D'Anjou , M. B. Plenio , J. Casanova

Nanomagnetometry using the nitrogen-vacancy (NV) centre in diamond has attracted a great deal of interest because of the combined features of room temperature operation, nanoscale resolution and high sensitivity. One of the important goals…

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