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The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.6 million retinal images, has demonstrated high adaptability…

Optical Coherence Tomography (OCT) imaging is pivotal in diagnosing ophthalmic conditions by providing detailed cross-sectional images of the anterior and posterior segments of the eye. Nonetheless, speckle noise and other imaging artifacts…

图像与视频处理 · 电气工程与系统科学 2024-09-26 Akkidas Noel Prakash , Jahnvi Sai Ganta , Ramaswami Krishnadas , Tin A. Tunc , Satish K Panda

Our research is motivated by the urgent global issue of a large population affected by retinal diseases, which are evenly distributed but underserved by specialized medical expertise, particularly in non-urban areas. Our primary objective…

计算机视觉与模式识别 · 计算机科学 2025-03-28 Deependra Singh , Saksham Agarwal , Subhankar Mishra

Optical Coherence Tomography (OCT) imaging plays an important role in glaucoma diagnosis in clinical practice. Early detection and timely treatment can prevent glaucoma patients from permanent vision loss. However, only a dearth of…

计算机视觉与模式识别 · 计算机科学 2019-07-31 Xi Wang , Hao Chen , Luyang Luo , An-ran Ran , Poemen P. Chan , Clement C. Tham , Carol Y. Cheung , Pheng-Ann Heng

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

图像与视频处理 · 电气工程与系统科学 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

People with diabetes are more likely to develop diabetic retinopathy (DR) than healthy people. However, DR is the leading cause of blindness. At present, the diagnosis of diabetic retinopathy mainly relies on the experienced clinician to…

计算机视觉与模式识别 · 计算机科学 2023-05-30 Zhuoyi Tan , Hizmawati Madzin , Zeyu Ding

3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However,…

图像与视频处理 · 电气工程与系统科学 2021-12-17 Zhuojie Wu , Zijian Wang , Wenxuan Zou , Fan Ji , Hao Dang , Wanting Zhou , Muyi Sun

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

图像与视频处理 · 电气工程与系统科学 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Optical Coherence Tomography (OCT) layer segmentation faces challenges due to annotation scarcity and heterogeneous label granularities across datasets. While semi-supervised learning helps alleviate label scarcity, existing methods…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Yizhou Fang , Jian Zhong , Li Lin , Xiaoying Tang

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

计算机视觉与模式识别 · 计算机科学 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Optical coherence tomography (OCT) is a non-invasive imaging modality which is widely used in clinical ophthalmology. OCT images are capable of visualizing deep retinal layers which is crucial for early diagnosis of retinal diseases. In…

计算机视觉与模式识别 · 计算机科学 2019-05-28 Peyman Gholami , Priyanka Roy , Mohana Kuppuswamy Parthasarathy , Vasudevan Lakshminarayanan

In this work, we propose Many-MobileNet, an efficient model fusion strategy for retinal disease classification using lightweight CNN architecture. Our method addresses key challenges such as overfitting and limited dataset variability by…

计算机视觉与模式识别 · 计算机科学 2024-12-05 Hao Wang , Wenhui Zhu , Xuanzhao Dong , Yanxi Chen , Xin Li , Peijie Qiu , Xiwen Chen , Vamsi Krishna Vasa , Yujian Xiong , Oana M. Dumitrascu , Abolfazl Razi , Yalin Wang

Deep learning has transformed computer vision but relies heavily on large labeled datasets and computational resources. Transfer learning, particularly fine-tuning pretrained models, offers a practical alternative; however, models…

计算机视觉与模式识别 · 计算机科学 2025-05-23 Iván Matas , Carmen Serrano , Miguel Nogales , David Moreno , Lara Ferrándiz , Teresa Ojeda , Begoña Acha

This paper considers making active learning more sensible from a medical perspective. In practice, a disease manifests itself in different forms across patient cohorts. Existing frameworks have primarily used mathematical constructs to…

图像与视频处理 · 电气工程与系统科学 2022-06-28 Yash-yee Logan , Ryan Benkert , Ahmad Mustafa , Gukyeong Kwon , Ghassan AlRegib

Inpainting shadowed regions cast by superficial blood vessels in retinal optical coherence tomography (OCT) images is critical for accurate and robust machine analysis and clinical diagnosis. Traditional sequence-based approaches such as…

计算机视觉与模式识别 · 计算机科学 2022-02-24 Yaoqi Tang , Yufan Li , Hongshan Liu , Jiaxuan Li , Peiyao Jin , Yu Gan , Yuye Ling , Yikai Su

We propose a hybrid sequential deep learning model to predict the risk of AMD progression in non-exudative AMD eyes at multiple timepoints, starting from short-term progression (3-months) up to long-term progression (21-months). Proposed…

定量方法 · 定量生物学 2019-03-01 Imon Banerjee , Luis de Sisternes , Joelle Hallak , Theodore Leng , Aaron Osborne , Mary Durbin , Daniel Rubin

Unlabeled data is often abundant in the clinic, making machine learning methods based on semi-supervised learning a good match for this setting. Despite this, they are currently receiving relatively little attention in medical image…

计算机视觉与模式识别 · 计算机科学 2020-10-26 Valentyn Melnychuk , Evgeniy Faerman , Ilja Manakov , Thomas Seidl

Cancer is a leading cause of death worldwide, necessitating advancements in early detection and treatment technologies. In this paper, we present a novel and highly efficient melanoma detection framework that synergistically combines the…

图像与视频处理 · 电气工程与系统科学 2024-08-05 Peng Zhang , Divya Chaudhary

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

The segmentation of the retinal vasculature from eye fundus images represents one of the most fundamental tasks in retinal image analysis. Over recent years, increasingly complex approaches based on sophisticated Convolutional Neural…

图像与视频处理 · 电气工程与系统科学 2020-09-07 Adrian Galdran , André Anjos , José Dolz , Hadi Chakor , Hervé Lombaert , Ismail Ben Ayed