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Objectives: To evaluate the performance of a deep learning based Artificial Intelligence (AI) software for detection of glaucoma from stereoscopic optic disc photographs, and to compare this performance to the performance of a large cohort…

计算机视觉与模式识别 · 计算机科学 2019-06-05 Thomas W. Rogers , Nicolas Jaccard , Francis Carbonaro , Hans G. Lemij , Koenraad A. Vermeer , Nicolaas J. Reus , Sameer Trikha

Diabetic Retinopathy (DR) is a major cause of global blindness, necessitating early and accurate diagnosis. While deep learning models have shown promise in DR detection, their black-box nature often hinders clinical adoption due to a lack…

计算机视觉与模式识别 · 计算机科学 2025-08-22 Masato Ito , Kaito Tanaka , Keisuke Matsuda , Aya Nakayama

Artificial intelligence methods have been increasingly turning into a potentially powerful tool in the diagnosis and management of diseases. In this study, we utilized logistic regression (LR), decision tree (DT), gradient boosted decision…

机器学习 · 计算机科学 2021-02-23 Chenglin Pan , Kuan Yan , Xiao Liu , Yanjie Chen , Yanyan Luo , Xiaoming Li , Zhenguo Nie , Xinjun Liu

The diagnosis of glaucoma plays a critical role in the management and treatment of this vision-threatening disease. Glaucoma is a group of eye diseases that cause blindness by damaging the optic nerve at the back of the eye. Often called…

图像与视频处理 · 电气工程与系统科学 2024-10-24 Yuki Hagiwara , Octavia-Andreea Ciora , Maureen Monnet , Gino Lancho , Jeanette Miriam Lorenz

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

计算机视觉与模式识别 · 计算机科学 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Developing interpretable models for neurodevelopmental disorders (NDDs) diagnosis presents significant challenges in effectively encoding, decoding, and integrating multimodal neuroimaging data. While many existing machine learning…

计算机视觉与模式识别 · 计算机科学 2026-04-24 Yueyang Li , Lei Chen , Wenhao Dong , Shengyu Gong , Zijian Kang , Boyang Wei , Weiming Zeng , Hongjie Yan , Lingbin Bian , Zhiguo Zhang , Wai Ting Siok , Nizhuan Wang

Medical diagnosis prediction plays a critical role in disease detection and personalized healthcare. While machine learning (ML) models have been widely adopted for this task, their reliance on supervised training limits their ability to…

人工智能 · 计算机科学 2025-07-08 Yuzhang Xie , Hejie Cui , Ziyang Zhang , Jiaying Lu , Kai Shu , Fadi Nahab , Xiao Hu , Carl Yang

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

计算机视觉与模式识别 · 计算机科学 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Cardiovascular disease (CVD) remains the foremost cause of mortality worldwide, underscoring the urgent need for intelligent and data-driven diagnostic tools. Traditional predictive models often struggle to generalize across heterogeneous…

人工智能 · 计算机科学 2026-01-27 Rajan Das Gupta , Xiaobin Wu , Xun Liu , Jiaqi He

For safety, medical AI systems undergo thorough evaluations before deployment, validating their predictions against a ground truth which is assumed to be fixed and certain. However, this ground truth is often curated in the form of…

Nearly one in five adolescents currently live with a diagnosed mental or behavioral health condition, such as anxiety, depression, or conduct disorder, underscoring the urgency of developing accurate and interpretable diagnostic tools.…

机器学习 · 计算机科学 2025-10-07 Song Wang , Zhenyu Lei , Zhen Tan , Jundong Li , Javier Rasero , Aiying Zhang , Chirag Agarwal

Diabetic retinopathy (DR) grading is crucial in determining the adequate treatment and follow up of patients, but the screening process can be tiresome and prone to errors. Deep learning approaches have shown promising performance as…

图像与视频处理 · 电气工程与系统科学 2020-06-01 Teresa Araújo , Guilherme Aresta , Luís Mendonça , Susana Penas , Carolina Maia , Ângela Carneiro , Ana Maria Mendonça , Aurélio Campilho

Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

人工智能 · 计算机科学 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

We propose a novel and interpretable embedding method to represent the international statistical classification codes of diseases and related health problems (i.e., ICD codes). This method considers a self-attention mechanism within the…

应用统计 · 统计学 2019-06-14 Dixin Luo , Hongteng Xu , Lawrence Carin

The black-box nature of machine learning models hinders the deployment of some high-accuracy models in medical diagnosis. It is risky to put one's life in the hands of models that medical researchers do not fully understand. However,…

Concept Bottleneck Models (CBMs) are a prominent framework for interpretable AI that map learned visual features to a set of meaningful concepts for task-specific downstream predictions. Their sequential structure enhances transparency by…

Precision medicine, tailored to individual patients based on their genetics, environment, and lifestyle, shows promise in managing complex diseases like infections. Integrating artificial intelligence (AI) into precision medicine can…

其他定量生物学 · 定量生物学 2023-07-31 Ghizal fatima , Risala H. Allami , Maitham G. Yousif

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

图像与视频处理 · 电气工程与系统科学 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Appendicitis is among the most frequent reasons for pediatric abdominal surgeries. Previous decision support systems for appendicitis have focused on clinical, laboratory, scoring, and computed tomography data and have ignored abdominal…

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves
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