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Metastasis on lymph nodes (LNs), the most common way of spread for primary tumor cells, is a sign of increased mortality. However, metastatic LNs are time-consuming and challenging to detect even for professional radiologists due to their…

图像与视频处理 · 电气工程与系统科学 2023-01-10 Chaoyi Wu , Feng Chang , Xiao Su , Zhihan Wu , Yanfeng Wang , Ling Zhu , Ya Zhang

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

图像与视频处理 · 电气工程与系统科学 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

The success of deep convolutional neural networks is partially attributed to the massive amount of annotated training data. However, in practice, medical data annotations are usually expensive and time-consuming to be obtained. Considering…

图像与视频处理 · 电气工程与系统科学 2020-10-06 Kang Li , Lequan Yu , Shujun Wang , Pheng-Ann Heng

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

计算机视觉与模式识别 · 计算机科学 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Addressing missing modalities presents a critical challenge in multimodal learning. Current approaches focus on developing models that can handle modality-incomplete inputs during inference, assuming that the full set of modalities are…

计算机视觉与模式识别 · 计算机科学 2024-06-05 Yunpeng Zhao , Cheng Chen , Qing You Pang , Quanzheng Li , Carol Tang , Beng-Ti Ang , Yueming Jin

A common assumption in multimodal learning is the completeness of training data, i.e., full modalities are available in all training examples. Although there exists research endeavor in developing novel methods to tackle the incompleteness…

计算机视觉与模式识别 · 计算机科学 2021-03-11 Mengmeng Ma , Jian Ren , Long Zhao , Sergey Tulyakov , Cathy Wu , Xi Peng

Multimodal learning has increasingly become a focal point in research, primarily due to its ability to integrate complementary information from diverse modalities. Nevertheless, modality imbalance, stemming from factors such as insufficient…

机器学习 · 计算机科学 2025-11-04 Rongrong Xie , Guido Sanguinetti

Multimodal pathology-genomic analysis is critical for cancer survival prediction. However, existing approaches predominantly integrate formalin-fixed paraffin-embedded (FFPE) slides with genomic data, while neglecting the availability of…

计算机视觉与模式识别 · 计算机科学 2025-06-25 Mingcheng Qu , Guang Yang , Donglin Di , Yue Gao , Tonghua Su , Yang Song , Lei Fan

Multimodal clinical data are characterized by high dimensionality, heterogeneous representations, and structured missingness, posing significant challenges for predictive modeling, data integration, and interpretability. We propose BIONIC…

Metastatic presence in lymph nodes is one of the most important prognostic variables of breast cancer. The current diagnostic procedure for manually reviewing sentinel lymph nodes, however, is very time-consuming and subjective.…

计算机视觉与模式识别 · 计算机科学 2016-08-05 Richard Chen , Yating Jing , Hunter Jackson

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

机器学习 · 计算机科学 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

图像与视频处理 · 电气工程与系统科学 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

With the development of radiomics, noninvasive diagnosis like ultrasound (US) imaging plays a very important role in automatic liver fibrosis diagnosis (ALFD). Due to the noisy data, expensive annotations of US images, the application of…

计算机视觉与模式识别 · 计算机科学 2020-11-03 Lufei Gao , Ruisong Zhou , Changfeng Dong , Cheng Feng , Zhen Li , Xiang Wan , Li Liu

Multiple Instance Learning (MIL) plays a significant role in computational pathology, enabling weakly supervised analysis of Whole Slide Image (WSI) datasets. The field of WSI analysis is confronted with a severe long-tailed distribution…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Xitong Ling , Yifeng Ping , Jiawen Li , Jing Peng , Yuxuan Chen , Minxi Ouyang , Yizhi Wang , Yonghong He , Tian Guan , Xiaoping Liu , Lianghui Zhu

Leveraging multimodal information from Magnetic Resonance Imaging (MRI) plays a vital role in lesion segmentation, especially for brain tumors. However, in clinical practice, multimodal MRI data are often incomplete, making it challenging…

计算机视觉与模式识别 · 计算机科学 2026-01-01 Yulong Zou , Bo Liu , Cun-Jing Zheng , Yuan-ming Geng , Siyue Li , Qiankun Zuo , Shuihua Wang , Yudong Zhang , Jin Hong

Multimodal learning has achieved great successes in many scenarios. Compared with unimodal learning, it can effectively combine the information from different modalities to improve the performance of learning tasks. In reality, the…

机器学习 · 计算机科学 2021-08-25 Fei Ma , Xiangxiang Xu , Shao-Lun Huang , Lin Zhang

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

计算机视觉与模式识别 · 计算机科学 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

In recent years, multimodal medical data-based survival analysis has attracted much attention. However, real-world datasets often suffer from the problem of incomplete modality, where some patient modality information is missing due to…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Yi Yin , Yuntao Shou , Zao Dai , Yun Peng , Tao Meng , Wei Ai , Keqin Li

Determining lymphoma subtypes is a crucial step for better patient treatment targeting to potentially increase their survival chances. In this context, the existing gold standard diagnosis method, which relies on gene expression technology,…

图像与视频处理 · 电气工程与系统科学 2024-07-24 Bilel Guetarni , Feryal Windal , Halim Benhabiles , Marianne Petit , Romain Dubois , Emmanuelle Leteurtre , Dominique Collard