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Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, affecting up to 45% of patients. They are often underdiagnosed due to overlapping motor…

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Parkinson's Disease (PD) is one of the most prevalent neurodegenerative diseases that affects tens of millions of Americans. PD is highly progressive and heterogeneous. Quite a few studies have been conducted in recent years on predictive…

计算机视觉与模式识别 · 计算机科学 2019-05-08 Xi Sheryl Zhang , Lifang He , Kun Chen , Yuan Luo , Jiayu Zhou , Fei Wang

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

计算与语言 · 计算机科学 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerged as a powerful tool to enhance PD classification and diagnostic accuracy, particularly by…

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide and affects around 1% of the (60+ years old) elderly population in industrial nations. More than 80% of PD patients suffer from motor symptoms, which…

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Parkinsons disease, the fastest growing neurodegenerative disorder globally, has seen a 50 percent increase in cases within just two years. As speech, memory, and motor symptoms worsen over time, early diagnosis is crucial for preserving…

定量方法 · 定量生物学 2024-12-02 Diya Vatsavai , Anya Iyer , Ashwin A. Nair

Parkinson's disease (PD) is a progressive neurodegenerative disorder that impacts motor functions and speech characteristics This study focuses on differentiating individuals with Parkinson's disease from healthy controls through the…

机器学习 · 计算机科学 2025-01-27 Burak Çelik , Ayhan Akbal

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

机器学习 · 计算机科学 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

神经元与认知 · 定量生物学 2014-05-07 Pooja Chandrashekar

Parkinson's disease (PD) is a progressive degenerative disorder of the central nervous system characterized by motor and non-motor symptoms. As the disease progresses, patients alternate periods in which motor symptoms are mitigated due to…

音频与语音处理 · 电气工程与系统科学 2020-08-26 Anna Pompili , Rubén Solera-Ureña , Alberto Abad , Rita Cardoso , Isabel Guimarães , Margherita Fabbri , Isabel P. Martins , Joaquim Ferreira

Parkinson's disease (PD) is a progressive neurodegenerative disorder that results in a variety of motor dysfunction symptoms, including tremors, bradykinesia, rigidity and postural instability. The diagnosis of PD mainly relies on clinical…

计算机视觉与模式识别 · 计算机科学 2022-07-15 Haozheng Zhang , Edmond S. L. Ho , Xiatian Zhang , Hubert P. H. Shum

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Recently, there has been a growing interest in developing automatic tools that can assess motor function in PD patients.…

信息检索 · 计算机科学 2018-05-04 Liron Allerhand , Brit Youngmann , Elad Yom-Tov , David Arkadir

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

信号处理 · 电气工程与系统科学 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

机器学习 · 计算机科学 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

In this work, we use a deep learning framework for simultaneous classification and regression of Parkinson disease diagnosis based on MR-Images and personal information (i.e. age, gender). We intend to facilitate and increase the confidence…

计算机视觉与模式识别 · 计算机科学 2018-06-15 Soheil Esmaeilzadeh , Yao Yang , Ehsan Adeli

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

计算机视觉与模式识别 · 计算机科学 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

应用统计 · 统计学 2018-10-04 R Prashanth , Sumantra Dutta Roy