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Spiral waves are self-repeating waves that can form in excitable media, propagating outward from their center in a spiral pattern. Spiral waves have been observed in different natural phenomena and have been linked to medical conditions…

元胞自动机与格子气 · 物理学 2020-08-11 Vincent Vangelista , Karl Amjad-Ali , Minhyeok Kwon , Paulo H. Acioli

In medical imaging, generative models are increasingly relied upon for two distinct but equally critical tasks: reconstruction, where the goal is to restore medical imaging (usually inverse problems like inpainting or superresolution), and…

图像与视频处理 · 电气工程与系统科学 2025-07-28 Niklas Bubeck , Yundi Zhang , Suprosanna Shit , Daniel Rueckert , Jiazhen Pan

Within cardiovascular disease detection using deep learning applied to ECG signals, the complexities of handling physiological signals have sparked growing interest in leveraging deep generative models for effective data augmentation. In…

计算机视觉与模式识别 · 计算机科学 2024-05-06 Nour Neifar , Achraf Ben-Hamadou , Afef Mdhaffar , Mohamed Jmaiel

Abnormal electrical activity from the boundaries of ischemic cardiac tissue is recognized as one of the major causes in generation of ischemia-reperfusion arrhythmias. Here we present theoretical analysis of the waves of electrical activity…

组织与器官 · 定量生物学 2015-05-19 Vadim N. Biktashev , Irina V. Biktasheva , Narine A. Sarvazyan

This work reports the results of the theoretical investigation of nonlinear dynamics and spiral wave breakup in a generalized two-variable model of cardiac action potential accounting for thermo-electric coupling and diffusion…

组织与器官 · 定量生物学 2018-11-07 A. Gizzi , A. Loppini , R. Ruiz-Baier , A. Ippolito , A. Camassa , A. La Camera , E. Emmi , L. Di Perna , V. Garofalo , C. Cherubini , S. Filippi

Human trajectory data is crucial in urban planning, traffic engineering, and public health. However, directly using real-world trajectory data often faces challenges such as privacy concerns, data acquisition costs, and data quality. A…

机器学习 · 计算机科学 2025-11-05 Qingyue Long , Can Rong , Tong Li , Yong Li

Living cells employ excitable reaction-diffusion waves for internal cellular functions, in which curvature-inducing proteins are often involved. However, the role of their mechanochemical coupling is not well understood. Here, we report the…

软凝聚态物质 · 物理学 2022-08-09 Naoki Tamemoto , Hiroshi Noguchi

We present an investigation into diffusion models for molecular generation, with the aim of better understanding how their predictions compare to the results of physics-based calculations. The investigation into these models is driven by…

Using statistical physics methods, we study generative diffusion models in the regime where the dimension of space and the number of data are large, and the score function has been trained optimally. Our analysis reveals three distinct…

机器学习 · 计算机科学 2025-01-08 Giulio Biroli , Tony Bonnaire , Valentin de Bortoli , Marc Mézard

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three spatial dimensions. Examples include waves during a pandemic…

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional…

机器学习 · 计算机科学 2025-10-23 Daniel Wesego

The oscillations observed in many time series, particularly in biomedicine, exhibit morphological variations over time. These morphological variations are caused by intrinsic or extrinsic changes to the state of the generating system,…

应用统计 · 统计学 2021-03-30 Yu-Ting Lin , John Malik , Hau-Tieng Wu

The heart's contraction is caused by electrical excitation which propagates through the heart muscle. It was recently shown that the electrical excitation can be computed from the contractile motion of a simulated piece of heart muscle…

医学物理 · 物理学 2023-05-16 Jan Lebert , Daniel Deng , Lei Fan , Lik Chuan Lee , Jan Christoph

We provide an overview of the diffusion model as a method to generate new samples. Generative models have been recently adopted for tasks such as art generation (Stable Diffusion, Dall-E) and text generation (ChatGPT). Diffusion models in…

机器学习 · 统计学 2025-06-13 Justin Le

Excitable tissue is fundamental to brain function, yet its study is complicated by extreme morphological complexity and the physiological processes governing its dynamics. Consequently, detailed computational modeling of this tissue…

Diffusion models have shown promising results for a wide range of generative tasks with continuous data, such as image and audio synthesis. However, little progress has been made on using diffusion models to generate discrete symbolic music…

声音 · 计算机科学 2023-10-24 Jincheng Zhang , György Fazekas , Charalampos Saitis

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

Scroll wave chaos is thought to underlie life-threatening ventricular fibrillation. However, currently there is no direct way to measure action potential wave patterns transmurally throughout the thick ventricular heart muscle.…

组织与器官 · 定量生物学 2023-02-08 Jan Lebert , Meenakshi Mittal , Jan Christoph

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

图像与视频处理 · 电气工程与系统科学 2022-06-28 Boah Kim , Jong Chul Ye

The design of aerodynamic shapes, such as airfoils, has traditionally required significant computational resources and relied on predefined design parameters, which limit the potential for novel shape synthesis. In this work, we introduce a…

机器学习 · 计算机科学 2024-12-19 Reid Graves , Amir Barati Farimani
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