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Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo

In the following short article we adapt a new and popular machine learning model for inference on medical data sets. Our method is based on the Variational AutoEncoder (VAE) framework that we adapt to survival analysis on small data sets…

机器学习 · 统计学 2018-12-06 Cédric Beaulac , Jeffrey S. Rosenthal , David Hodgson

Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

机器学习 · 计算机科学 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

Structured variational autoencoders (SVAEs) combine probabilistic graphical model priors on latent variables, deep neural networks to link latent variables to observed data, and structure-exploiting algorithms for approximate posterior…

机器学习 · 统计学 2023-05-29 Yixiu Zhao , Scott W. Linderman

The application of deep learning in survival analysis (SA) allows utilizing unstructured and high-dimensional data types uncommon in traditional survival methods. This allows to advance methods in fields such as digital health, predictive…

机器学习 · 计算机科学 2021-11-18 Tobias Weber , Michael Ingrisch , Bernd Bischl , David Rügamer

The surrogate loss of variational autoencoders (VAEs) poses various challenges to their training, inducing the imbalance between task fitting and representation inference. To avert this, the existing strategies for VAEs focus on adjusting…

神经与进化计算 · 计算机科学 2024-04-02 Zhangkai Wu , Longbing Cao , Lei Qi

This paper provides a comprehensive analysis of variational inference in latent variable models for survival analysis, emphasizing the distinctive challenges associated with applying variational methods to survival data. We identify a…

机器学习 · 计算机科学 2025-06-05 Chuanhui Liu , Xiao Wang

Probabilistic generative models are attractive for scientific modeling because their inferred parameters can be used to generate hypotheses and design experiments. This requires that the learned model provide an accurate representation of…

机器学习 · 统计学 2023-01-18 Liyun Tu , Austin Talbot , Neil Gallagher , David Carlson

Is there really much more to say about sparse autoencoders (SAEs)? Autoencoders in general, and SAEs in particular, represent deep architectures that are capable of modeling low-dimensional latent structure in data. Such structure could…

机器学习 · 计算机科学 2025-06-09 Yin Lu , Xuening Zhu , Tong He , David Wipf

Variational autoencoders (VAEs) have been used extensively to discover low-dimensional latent factors governing neural activity and animal behavior. However, without careful model selection, the uncovered latent factors may reflect noise in…

机器学习 · 计算机科学 2023-12-13 Julia Huiming Wang , Dexter Tsin , Tatiana Engel

Often the analysis of time-dependent chemical and biophysical systems produces high-dimensional time-series data for which it can be difficult to interpret which individual features are most salient. While recent work from our group and…

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

The SAVVY project aims to improve the analyses of adverse events (AEs) in clinical trials through the use of survival techniques appropriately dealing with varying follow-up times and competing events (CEs). This paper summarizes key…

应用统计 · 统计学 2024-02-28 Kaspar Rufibach , Jan Beyersmann , Tim Friede , Claudia Schmoor , Regina Stegherr

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

The variational autoencoder (VAE) is a popular deep latent variable model used to analyse high-dimensional datasets by learning a low-dimensional latent representation of the data. It simultaneously learns a generative model and an…

机器学习 · 计算机科学 2023-11-21 Mine Öğretir , Siddharth Ramchandran , Dimitrios Papatheodorou , Harri Lähdesmäki

Syntactic information contains structures and rules about how text sentences are arranged. Incorporating syntax into text modeling methods can potentially benefit both representation learning and generation. Variational autoencoders (VAEs)…

计算与语言 · 计算机科学 2019-08-28 Yijun Xiao , William Yang Wang

We present the development of a semi-supervised regression method using variational autoencoders (VAE), which is customized for use in soft sensing applications. We motivate the use of semi-supervised learning considering the fact that…

机器学习 · 计算机科学 2022-12-12 Yilin Zhuang , Zhuobin Zhou , Burak Alakent , Mehmet Mercangöz

By composing graphical models with deep learning architectures, we learn generative models with the strengths of both frameworks. The structured variational autoencoder (SVAE) inherits structure and interpretability from graphical models,…

机器学习 · 计算机科学 2023-11-15 Harry Bendekgey , Gabriel Hope , Erik B. Sudderth

Although the Conditional Variational AutoEncoder (CVAE) model can generate more diversified responses than the traditional Seq2Seq model, the responses often have low relevance with the input words or are illogical with the question. A…

计算与语言 · 计算机科学 2022-10-12 Jiayi Liu , Wei Wei , Zhixuan Chu , Xing Gao , Ji Zhang , Tan Yan , Yulin Kang

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

机器学习 · 计算机科学 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka
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