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In recent years, the lack of reproducibility of research findings has become an important source of concerns in many scientific fields, including functional Magnetic Resonance Imaging (fMRI). The low statistical power often observed in fMRI…

神经元与认知 · 定量生物学 2024-02-21 Elodie Germani , Xavier Rolland , Pierre Maurel , Camille Maumet

The development of foundation models for brain MRI depends critically on the scale, diversity, and consistency of available data, yet systematic assessments of these factors remain scarce. In this study, we analyze 54 publicly accessible…

计算机视觉与模式识别 · 计算机科学 2025-10-24 Minh Sao Khue Luu , Margaret V. Benedichuk , Ekaterina I. Roppert , Roman M. Kenzhin , Bair N. Tuchinov

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

神经元与认知 · 定量生物学 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Resting-state fMRI has been shown to provide surrogate biomarkers for the analysis of various diseases. In addition, fMRI data helps in understanding the brain's functional working during resting state and task-induced activity. To improve…

机器学习 · 计算机科学 2021-10-11 Dushyant Sahoo , Christos Davatzikos

Deep learning has been widely applied in neuroimaging, including predicting brain-phenotype relationships from magnetic resonance imaging (MRI) volumes. MRI data usually requires extensive preprocessing prior to modeling, but variation…

机器学习 · 计算机科学 2023-10-17 Xinhui Li , Alex Fedorov , Mrinal Mathur , Anees Abrol , Gregory Kiar , Sergey Plis , Vince Calhoun

A bioinformatics platform is introduced aimed at identifying models of disease-specific pathways, as well as a set of network measures that can quantify changes in terms of global structure or single link disruptions.The approach integrates…

分子网络 · 定量生物学 2012-01-17 A. Barla , S. Riccadonna , S. Masecchia , M. Squillario , M. Filosi , G. Jurman , C. Furlanello

Correlation matrices are widely used to analyze the interdependence of variables in various real-world scenarios. Often, a perturbation in a few variables leads to mild differences in many correlation coefficients associated with these…

应用统计 · 统计学 2023-03-07 Itamar Faran , Michael Peer , Shahar Arzy , Yuval Benjamini

The technology of functional Magnetic Resonance Imaging (fMRI) based on Blood Oxygen Level Dependent (BOLD) signal has been widely used in clinical treatments and brain function researches. The BOLD signal has to be preprocessed before…

神经元与认知 · 定量生物学 2017-12-29 Yunxiang Ge , Yu Pan , Weibei Dou

In neuroimaging, extensive post-processing of resting-state functional MRI (rfMRI) data is necessary for its application and investigation in relation to brain-behavior associations. Such post-processing is used to derive brain…

计算几何 · 计算机科学 2025-09-11 Ty Easley , Kevin Freese , Elizabeth Munch , Janine Bijsterbosch

Functional magnetic resonance imaging (fMRI) produces data about activity inside the brain, from which spatial maps can be extracted by independent component analysis (ICA). In datasets, there are n spatial maps that contain p voxels. The…

计算工程、金融与科学 · 计算机科学 2016-11-17 Tuomo Sipola , Fengyu Cong , Tapani Ristaniemi , Vinoo Alluri , Petri Toiviainen , Elvira Brattico , Asoke K. Nandi

Statistical analysis of multimodal imaging data is a challenging task, since the data involves high-dimensionality, strong spatial correlations and complex data structures. In this paper, we propose rigorous statistical testing procedures…

统计方法学 · 统计学 2023-03-08 Jinyuan Chang , Jing He , Jian Kang , Mingcong Wu

Diffusion Magnetic Resonance Imaging (dMRI) is sensitive to white matter (WM) changes across the human lifespan. Several models have been proposed to provide more specific metrics than those provided by the conventional Diffusion Tensor…

医学物理 · 物理学 2023-06-19 Rafael Neto Henriques1 , Richard Henson , Cam-CAN , Marta Morgado Correia

Functional magnetic resonance (fMRI) is an invaluable tool in studying cognitive processes in vivo. Many recent studies use functional connectivity (FC), partial correlation connectivity (PC), or fMRI-derived brain networks to predict…

神经元与认知 · 定量生物学 2023-08-04 Anton Orlichenko , Gang Qu , Kuan-Jui Su , Anqi Liu , Hui Shen , Hong-Wen Deng , Yu-Ping Wang

Even though novel imaging techniques have been successful in studying brain structure and function, the measured biological signals are often contaminated by multiple sources of noise, arising due to e.g. head movements of the individual…

计算机视觉与模式识别 · 计算机科学 2025-05-20 Brice Ozenne , Martin Norgaard , Cyril Pernet , Melanie Ganz

This is an empirical study to investigate the impact of scanner effects when using machine learning on multi-site neuroimaging data. We utilize structural T1-weighted brain MRI obtained from two different studies, Cam-CAN and UK Biobank.…

图像与视频处理 · 电气工程与系统科学 2019-10-11 Ben Glocker , Robert Robinson , Daniel C. Castro , Qi Dou , Ender Konukoglu

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

Pooling publicly-available MRI data from multiple sites allows to assemble extensive groups of subjects, increase statistical power, and promote data reuse with machine learning techniques. The harmonization of multicenter data is necessary…

机器学习 · 计算机科学 2024-02-02 Chiara Marzi , Marco Giannelli , Andrea Barucci , Carlo Tessa , Mario Mascalchi , Stefano Diciotti

In this paper we review the preprocessing pipeline through which fMRI data is transformed into a network. We discuss three parameters that mostly affect our understanding of the existence of functional correlations between the brain…

神经元与认知 · 定量生物学 2022-02-07 Amin Kaveh , Matteo Magnani , Christian Rohner

Understanding the structure of the brain, and how it changes with time and disease, is a core goal of structural neuroimaging. Contemporary approaches to structural brain analysis are dominated by voxel-wise, mass-univariate methods such as…

代数拓扑 · 数学 2026-04-28 Donato Quiccione , Mariam Pirashvili , Nathan Broomhead , Sean J. Fallon
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