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Accurately discriminating progressive stages of Alzheimer's Disease (AD) is crucial for early diagnosis and prevention. It often involves multiple imaging modalities to understand the complex pathology of AD, however, acquiring a complete…

图像与视频处理 · 电气工程与系统科学 2025-03-06 Seunghun Baek , Jaeyoon Sim , Guorong Wu , Won Hwa Kim

Mild cognitive impairment (MCI) is often at high risk of progression to Alzheimer's disease (AD). Existing works to identify the progressive MCI (pMCI) typically require MCI subtype labels, pMCI vs. stable MCI (sMCI), determined by whether…

图像与视频处理 · 电气工程与系统科学 2024-01-24 Chenhui Wang , Yiming Lei , Tao Chen , Junping Zhang , Yuxin Li , Hongming Shan

Labeled data is a fundamental component in training supervised deep learning models for computer vision tasks. However, the labeling process, especially for ordinal image classification where class boundaries are often ambiguous, is prone…

计算机视觉与模式识别 · 计算机科学 2026-05-19 Alireza Sedighi Moghaddam , Mohammad Reza Mohammadi

Dynamic treatment regimens (DTRs) are sequential decision rules tailored at each stage by potentially time-varying patient features and intermediate outcomes observed in previous stages. The complexity, patient heterogeneity and chronicity…

统计方法学 · 统计学 2016-11-09 Ying Liu , Yuanjia Wang , Michael R. Kosorok , Yingqi Zhao , Donglin Zeng

Modern systems that rely on Machine Learning (ML) for predictive modelling, may suffer from the cold-start problem: supervised models work well but, initially, there are no labels, which are costly or slow to obtain. This problem is even…

Many real-world datasets are labeled with natural orders, i.e., ordinal labels. Ordinal regression is a method to predict ordinal labels that finds a wide range of applications in data-rich domains, such as natural, health and social…

机器学习 · 计算机科学 2020-04-28 Lu Wang , Dongxiao Zhu

Online Active Learning (OAL) aims to manage unlabeled datastream by selectively querying the label of data. OAL is applicable to many real-world problems, such as anomaly detection in health-care and finance. In these problems, there are…

机器学习 · 计算机科学 2019-11-19 Yifan Zhang , Peilin Zhao , Shuaicheng Niu , Qingyao Wu , Jiezhang Cao , Junzhou Huang , Mingkui Tan

Modeling a system's temporal behaviour in reaction to external stimuli is a fundamental problem in many areas. Pure Machine Learning (ML) approaches often fail in the small sample regime and cannot provide actionable insights beyond…

机器学习 · 计算机科学 2021-06-18 Zhaozhi Qian , William R. Zame , Lucas M. Fleuren , Paul Elbers , Mihaela van der Schaar

Learning with reduced labeling standards, such as noisy label, partial label, and multiple label candidates, which we generically refer to as \textit{imprecise} labels, is a commonplace challenge in machine learning tasks. Previous methods…

机器学习 · 计算机科学 2024-10-31 Hao Chen , Ankit Shah , Jindong Wang , Ran Tao , Yidong Wang , Xing Xie , Masashi Sugiyama , Rita Singh , Bhiksha Raj

Precision medicine is of considerable interest in clinical, academic and regulatory parties. The key to precision medicine is the optimal treatment regime. Recently, Zhou et al. (2017) developed residual weighted learning (RWL) to construct…

统计方法学 · 统计学 2017-11-30 Xin Zhou , Michael R. Kosorok

Objective: We aimed to develop and validate a novel multimodal framework HiMAL (Hierarchical, Multi-task Auxiliary Learning) framework, for predicting cognitive composite functions as auxiliary tasks that estimate the longitudinal risk of…

机器学习 · 计算机科学 2026-02-06 Sayantan Kumar , Sean Yu , Andrew Michelson , Thomas Kannampallil , Philip Payne

Pool-based active learning (AL) is a promising technology for increasing data-efficiency of machine learning models. However, surveys show that performance of recent AL methods is very sensitive to the choice of dataset and training…

机器学习 · 计算机科学 2023-09-12 Tim Bakker , Herke van Hoof , Max Welling

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Ordinal regression (OR) is classification of ordinal data in which the underlying categorical target variable has a natural ordinal relation for the underlying explanatory variable. For $K$-class OR tasks, threshold methods learn a…

机器学习 · 计算机科学 2024-05-22 Ryoya Yamasaki , Toshiyuki Tanaka

Model-based deep learning methods that combine imaging physics with learned regularization priors have been emerging as powerful tools for parallel MRI acceleration. The main focus of this paper is to determine the utility of the monotone…

机器学习 · 计算机科学 2023-04-05 Aniket Pramanik , Mathews Jacob

Learning from noisy ordinal labels is a key challenge in medical imaging. In this work, we ask whether ordinal disease progression labels (better, worse, or stable) can be used to learn a representation allowing to classify disease state.…

计算机视觉与模式识别 · 计算机科学 2025-08-08 Gustav Schmidt , Holger Heidrich , Philipp Berens , Sarah Müller

Deep learning models have been successfully used in medical image analysis problems but they require a large amount of labeled images to obtain good performance.Deep learning models have been successfully used in medical image analysis…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Asim Smailagic , Hae Young Noh , Pedro Costa , Devesh Walawalkar , Kartik Khandelwal , Mostafa Mirshekari , Jonathon Fagert , Adrián Galdrán , Susu Xu

Ordinal regression is commonly formulated as a multi-class problem with ordinal constraints. The challenge of designing accurate classifiers for ordinal regression generally increases with the number of classes involved, due to the large…

机器学习 · 计算机科学 2015-03-18 Chun-Wei Seah , Ivor W. Tsang , Yew-Soon Ong

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Active learning (AL) is a learning paradigm where an active learner has to train a model (e.g., a classifier) which is in principal trained in a supervised way, but in AL it has to be done by means of a data set with initially unlabeled…

机器学习 · 计算机科学 2015-12-23 Adrian Calma , Tobias Reitmaier , Bernhard Sick , Paul Lukowicz , Mark Embrechts
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