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Recently, large language models (LLMs) have outperformed human experts in predicting the results of neuroscience experiments (Luo et al., 2024). What is the basis for this performance? One possibility is that statistical patterns in that…

神经元与认知 · 定量生物学 2024-07-03 Xiaoliang Luo , Guangzhi Sun , Bradley C. Love

The advent of Large Language Models (LLMs) has ushered in a new era for design science in Information Systems, demanding a paradigm shift in tailoring LLMs design for business contexts. We propose and test a novel framework to customize…

计算机与社会 · 计算机科学 2024-05-15 Wen Wang , Zhenyue Zhao , Tianshu Sun

The recent success of Large Language Models (LLMs) has had a significant impact on the healthcare field, providing patients with medical advice, diagnostic information, and more. However, due to a lack of professional medical knowledge,…

计算与语言 · 计算机科学 2024-06-27 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Xiang Wan , Feng Jiang , Benyou Wang

Humankind's understanding of the world is fundamentally linked to our perception and cognition, with \emph{human languages} serving as one of the major carriers of \emph{world knowledge}. In this vein, \emph{Large Language Models} (LLMs)…

人工智能 · 计算机科学 2024-06-27 Huajun Chen

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

计算与语言 · 计算机科学 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

With the proliferation of large language models (LLMs) in the medical domain, there is increasing demand for improved evaluation techniques to assess their capabilities. However, traditional metrics like F1 and ROUGE, which rely on token…

计算与语言 · 计算机科学 2025-05-20 Xiechi Zhang , Zetian Ouyang , Linlin Wang , Gerard de Melo , Zhu Cao , Xiaoling Wang , Ya Zhang , Yanfeng Wang , Liang He

Integrating large language models (LLMs) into healthcare holds great potential but faces challenges. Pre-training LLMs from scratch for domains like medicine is resource-heavy and often unfeasible. On the other hand, sole reliance on…

计算与语言 · 计算机科学 2024-04-18 Qichen Ye , Junling Liu , Dading Chong , Peilin Zhou , Yining Hua , Fenglin Liu , Meng Cao , Ziming Wang , Xuxin Cheng , Zhu Lei , Zhenhua Guo

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

人工智能 · 计算机科学 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

In practice, clinicians achieve a diagnosis by following a sequence of steps, such as laboratory exams, observations, or imaging. The pathways to reach diagnosis decisions are documented by guidelines authored by expert organizations, which…

计算与语言 · 计算机科学 2024-09-25 Elisa Castagnari , Lillian Muyama , Adrien Coulet

Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

计算与语言 · 计算机科学 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

This research paper discusses the advances made in the past decade in biomedicine and Large Language Models. To understand how the advances have been made hand-in-hand with one another, the paper also discusses the integration of Natural…

计算与语言 · 计算机科学 2024-06-26 Michael Ackerman

Multimodal large language models (MLLMs) have shown remarkable potential in various domains, yet their application in the medical field is hindered by several challenges. General-purpose MLLMs often lack the specialized knowledge required…

人工智能 · 计算机科学 2025-09-29 Guanghao Zhu , Zhitian Hou , Zeyu Liu , Zhijie Sang , Congkai Xie , Hongxia Yang

Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

计算与语言 · 计算机科学 2024-08-23 Raphael Poulain , Hamed Fayyaz , Rahmatollah Beheshti

Artificial intelligence (AI) has gained significant attention in healthcare consultation due to its potential to improve clinical workflow and enhance medical communication. However, owing to the complex nature of medical information, large…

计算与语言 · 计算机科学 2024-03-05 Xiaolan Chen , Ziwei Zhao , Weiyi Zhang , Pusheng Xu , Le Gao , Mingpu Xu , Yue Wu , Yinwen Li , Danli Shi , Mingguang He

Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

The existing methods for evaluating the medical knowledge of Large Language Models (LLMs) are largely based on atemporal examination-style benchmarks, while in reality, medical knowledge is inherently dynamic and continuously evolves as new…

机器学习 · 计算机科学 2026-05-14 Zihan Guan , Qiao Jin , Guangzhi Xiong , Fangyuan Chen , Mengxuan Hu , Qingyu Chen , Yifan Peng , Zhiyong Lu , Anil Vullikanti

This project investigates the efficacy of Large Language Models (LLMs) in understanding and extracting scientific knowledge across specific domains and to create a deep learning framework: Knowledge AI. As a part of this framework, we…

计算与语言 · 计算机科学 2024-08-12 Balaji Muralidharan , Hayden Beadles , Reza Marzban , Kalyan Sashank Mupparaju

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

计算与语言 · 计算机科学 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large language models (LLMs) have been extensively studied for their abilities to generate convincing natural language sequences, however their utility for quantitative information retrieval is less well understood. Here we explore the…

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…