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Although deep learning approaches have had tremendous success in image, video and audio processing, computer vision, and speech recognition, their applications to three-dimensional (3D) biomolecular structural data sets have been hindered…

定量方法 · 定量生物学 2017-11-01 Zixuan Cang , Guo-Wei Wei

The segmentation of medical images is important for the improvement and creation of healthcare systems, particularly for early disease detection and treatment planning. In recent years, the use of convolutional neural networks (CNNs) and…

图像与视频处理 · 电气工程与系统科学 2024-01-12 Siddharth Tiwari

Recent advances in molecular representation learning have produced highly effective encodings of molecules for numerous cheminformatics and bioinformatics tasks. However, extracting general chemical insight while balancing predictive…

机器学习 · 计算机科学 2025-09-26 Rahul Khorana

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

计算机视觉与模式识别 · 计算机科学 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Persistent homology (PH) is a method for generating topology-inspired representations of data. Empirical studies that investigate the properties of PH, such as its sensitivity to perturbations or ability to detect a feature of interest,…

代数拓扑 · 数学 2024-03-05 Shuang Liang , Renata Turkeš , Jiayi Li , Nina Otter , Guido Montúfar

The hybrid architecture of convolutional neural networks (CNNs) and Transformer are very popular for medical image segmentation. However, it suffers from two challenges. First, although a CNNs branch can capture the local image features…

图像与视频处理 · 电气工程与系统科学 2023-12-21 Tao Lei , Rui Sun , Xuan Wang , Yingbo Wang , Xi He , Asoke Nandi

Deep Convolutional Neural Networks (CNNs) for image classification successively alternate convolutions and downsampling operations, such as pooling layers or strided convolutions, resulting in lower resolution features the deeper the…

计算机视觉与模式识别 · 计算机科学 2022-09-29 Ioannis Vezakis , Antonios Vezakis , Sofia Gourtsoyianni , Vassilis Koutoulidis , George K. Matsopoulos , Dimitrios Koutsouris

Graph-based neural network models are gaining traction in the field of representation learning due to their ability to uncover latent topological relationships between entities that are otherwise challenging to identify. These models have…

图像与视频处理 · 电气工程与系统科学 2023-07-25 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

[18F]-Fluorodeoxyglucose (FDG) positron emission tomography - computed tomography (PET-CT) has become the imaging modality of choice for diagnosing many cancers. Co-learning complementary PET-CT imaging features is a fundamental requirement…

图像与视频处理 · 电气工程与系统科学 2023-08-08 Lei Bi , Michael Fulham , Shaoli Song , David Dagan Feng , Jinman Kim

Segmenting curvilinear structures in medical images is essential for analyzing morphological patterns in clinical applications. Integrating topological properties, such as connectivity, improves segmentation accuracy and consistency.…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Zhuangzhi Gao , Feixiang Zhou , He Zhao , Xiuju Chen , Xiaoxin Li , Qinkai Yu , Yitian Zhao , Alena Shantsila , Gregory Y. H. Lip , Eduard Shantsila , Yalin Zheng

Persistent homology is a mathematical tool used for studying the shape of data by extracting its topological features. It has gained popularity in network science due to its applicability in various network mining problems, including…

代数拓扑 · 数学 2023-06-21 Mehmet Emin Aktas , Thu Nguyen , Rakin Riza , Muhammad Ifte Islam , Esra Akbas

Convolutional neural network (CNN) based methods have achieved great successes in medical image segmentation, but their capability to learn global representations is still limited due to using small effective receptive fields of convolution…

计算机视觉与模式识别 · 计算机科学 2022-11-17 Pengfei Gu , Yejia Zhang , Chaoli Wang , Danny Z. Chen

Automated medical image segmentation is becoming increasingly crucial to modern clinical practice, driven by the growing demand for precise diagnosis, the push towards personalized treatment plans, and the advancements in machine learning…

图像与视频处理 · 电气工程与系统科学 2023-11-13 Tan-Hanh Pham , Xianqi Li , Kim-Doang Nguyen

The convolutional neural network-based methods have become more and more popular for medical image segmentation due to their outstanding performance. However, they struggle with capturing long-range dependencies, which are essential for…

图像与视频处理 · 电气工程与系统科学 2024-01-30 Hongkun Sun , Jing Xu , Yuping Duan

Deep neural networks have been widely used in medical image analysis and medical image segmentation is one of the most important tasks. U-shaped neural networks with encoder-decoder are prevailing and have succeeded greatly in various…

图像与视频处理 · 电气工程与系统科学 2023-06-09 Juntao Jiang , Xiyu Chen , Guanzhong Tian , Yong Liu

The training of neural networks is usually monitored with a validation (holdout) set to estimate the generalization of the model. This is done instead of measuring intrinsic properties of the model to determine whether it is learning…

Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable successes of numerous image processing methods that rely on…

计算机视觉与模式识别 · 计算机科学 2025-08-05 Pengfei Gu , Hongxiao Wang , Yejia Zhang , Huimin Li , Chaoli Wang , Danny Chen

Persistent homology (PH) is one of the most popular methods in Topological Data Analysis. Even though PH has been used in many different types of applications, the reasons behind its success remain elusive; in particular, it is not known…

代数拓扑 · 数学 2023-01-18 Renata Turkeš , Guido Montúfar , Nina Otter

Convolutional Neural Networks (CNNs) have been successful in solving tasks in computer vision including medical image segmentation due to their ability to automatically extract features from unstructured data. However, CNNs are sensitive to…

图像与视频处理 · 电气工程与系统科学 2022-03-18 Minh Tran , Viet-Khoa Vo-Ho , Kyle Quinn , Hien Nguyen , Khoa Luu , Ngan Le

For Convolutional Neural Network-based object detection, there is a typical dilemma: the spatial information is well kept in the shallow layers which unfortunately do not have enough semantic information, while the deep layers have a high…

计算机视觉与模式识别 · 计算机科学 2020-05-08 Ziming Liu , Guangyu Gao , Lin Sun , Li Fang