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Real cortical tissue curves and folds according to experimental data. However, our current simulations only use unfolded cortical layers. This project extends the cortical slice model in order to be able to specify arbitrary curvatures to…

神经元与认知 · 定量生物学 2014-05-15 Jintao Long , Richard Tomsett , Marcus Kaiser

The brain's spatial orientation system uses different neuron ensembles to aid in environment-based navigation. Two of the ways brains encode spatial information is through head direction cells and grid cells. Brains use head direction cells…

神经与进化计算 · 计算机科学 2023-09-07 Edward C. Mitchell , Brittany Story , David Boothe , Piotr J. Franaszczuk , Vasileios Maroulas

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

计算机视觉与模式识别 · 计算机科学 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

Self-supervised topological deep learning (TDL) represents a nascent but underexplored area with significant potential for modeling higher-order interactions in simplicial complexes and cellular complexes to derive representations of…

机器学习 · 计算机科学 2025-05-29 Bin Qin , Qirui Ji , Jiangmeng Li , Yupeng Wang , Xuesong Wu , Jianwen Cao , Fanjiang Xu

The human brain displays a complex network topology, whose structural organization is widely studied using diffusion tensor imaging. The original geometry from which emerges the network topology is known, as well as the localization of the…

Cortical circuits exhibit intricate recurrent architectures that are remarkably similar across different brain areas. Such stereotyped structure suggests the existence of common computational principles. However, such principles have…

神经元与认知 · 定量生物学 2018-01-04 Rui Ponte Costa , Yannis M. Assael , Brendan Shillingford , Nando de Freitas , Tim P. Vogels

This paper presents a novel approach to learn and detect distinctive regions on 3D shapes. Unlike previous works, which require labeled data, our method is unsupervised. We conduct the analysis on point sets sampled from 3D shapes, then…

图形学 · 计算机科学 2020-04-22 Xianzhi Li , Lequan Yu , Chi-Wing Fu , Daniel Cohen-Or , Pheng-Ann Heng

Inferring synaptic connectivity from neural population activity is a fundamental challenge in computational neuroscience, complicated by partial observability and mismatches between inference models and true circuit dynamics. In this study,…

神经元与认知 · 定量生物学 2025-10-28 Kijung Yoon

Both biological cortico-thalamic networks and artificial transformer networks use canonical computations to perform a wide range of cognitive tasks. In this work, we propose that the structure of cortico-thalamic circuits is well suited to…

神经元与认知 · 定量生物学 2025-08-12 Arno Granier , Walter Senn

Functional brain graphs are often characterized with separate graph-theoretic or spectral descriptors, overlooking how these properties covary and partially overlap across brains and conditions. We anticipate that dense, weighted functional…

神经元与认知 · 定量生物学 2025-11-07 Subati Abulikemu , Tiago Azevedo , Michail Mamalakis , John Suckling

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

定量方法 · 定量生物学 2016-02-03 Sean L. Simpson , Paul J. Laurienti

Semantic segmentation of neuronal structures in 3D high-resolution fluorescence microscopy imaging of the human brain cortex can take advantage of bidimensional CNNs, which yield good results in neuron localization but lead to inaccurate…

图像与视频处理 · 电气工程与系统科学 2020-09-03 Filippo Maria Castelli , Matteo Roffilli , Giacomo Mazzamuto , Irene Costantini , Ludovico Silvestri , Francesco Saverio Pavone

In recent years, Convolutional Neural Networks (CNNs) have become the state-of-the-art method for biomedical image analysis. However, these networks are usually trained in a supervised manner, requiring large amounts of labelled training…

计算机视觉与模式识别 · 计算机科学 2020-11-24 Nastassya Horlava , Alisa Mironenko , Sebastian Niehaus , Sebastian Wagner , Ingo Roeder , Nico Scherf

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Precise segmentation of brain structures in magnetic resonance imaging (MRI) is essential for reliable neuroimaging analysis, yet voxel-wise deep models often yield anatomically inconsistent results that diverge from expert-defined…

计算机视觉与模式识别 · 计算机科学 2026-05-15 Ahmed Rekik , R. Jarrett Rushmore , Sylvain Bouix , Linda Marrakchi-Kacem

Recovering an image from a noisy observation is a key problem in signal processing. Recently, it has been shown that data-driven approaches employing convolutional neural networks can outperform classical model-based techniques, because…

图像与视频处理 · 电气工程与系统科学 2019-05-30 Diego Valsesia , Giulia Fracastoro , Enrico Magli

Estimating multiple attributes from a single facial image gives comprehensive descriptions on the high level semantics of the face. It is naturally regarded as a multi-task supervised learning problem with a single deep CNN, in which lower…

计算机视觉与模式识别 · 计算机科学 2018-10-23 Yan Zhang , Li Sun

Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…

计算机视觉与模式识别 · 计算机科学 2021-03-24 Xiang Li , Aoxiao Zhong , Ming Lin , Ning Guo , Mu Sun , Arkadiusz Sitek , Jieping Ye , James Thrall , Quanzheng Li

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

计算机视觉与模式识别 · 计算机科学 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

Detection and segmentation of the hippocampal structures in volumetric brain images is a challenging problem in the area of medical imaging. In this paper, we propose a two-stage 3D fully convolutional neural network that efficiently…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Dengsheng Chen , Wenxi Liu , You Huang , Tong Tong , Yuanlong Yu