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Chemical space which encompasses all stable compounds is unfathomably large and its dimension scales linearly with the number of atoms considered. The success of machine learning methods suggests that many physical quantities exhibit…

化学物理 · 物理学 2025-07-04 Ali Banjafar , Guido Falk von Rudorff

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

化学物理 · 物理学 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

The limited extrapolative power of structure-based machine learning (ML) models is a critical bottleneck in chemical discovery, particularly for industrial R&D, where navigating uncharted chemical space to find next-generation materials or…

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

We introduce property-independent kernels for machine learning modeling of arbitrarily many molecular properties. The kernels encode molecular structures for training sets of varying size, as well as similarity measures sufficiently diffuse…

化学物理 · 物理学 2015-03-18 Raghunathan Ramakrishnan , O. Anatole von Lilienfeld

We study the problem of space and time efficient evaluation of a nonparametric estimator that approximates an unknown density. In the regime where consistent estimation is possible, we use a piecewise multivariate polynomial interpolation…

统计理论 · 数学 2020-11-11 Paxton Turner , Jingbo Liu , Philippe Rigollet

Upcoming facilities such as the Herschel Space Observatory or ALMA will deliver a wealth of molecular line observations of young stellar objects (YSOs). Based on line fluxes, chemical abundances can then be estimated by radiative transfer…

太阳与恒星天体物理 · 物理学 2009-07-22 Simon Bruderer , Steven D. Doty , Arnold O. Benz

The interpolation of high-dimensional potential energy surfaces (PESs) is commonly done with physically-inspired deep-neural network models. In this work, we illustrate that Gaussian Processes (GPs) are also capable of interpolating…

化学物理 · 物理学 2021-09-30 Rodrigo A. Vargas-Hernández , Jake R. Gardner

We present a highly efficient molecular dynamics scheme for calculating the concentration profile of dopants implanted in group-IV alloy, and III-V zinc blende structure materials. Our program incorporates methods for reducing computational…

材料科学 · 物理学 2009-10-31 Keith M. Beardmore , Niels Gronbech-Jensen

We present ChemXploreML, a modular desktop application designed for machine learning-based molecular property prediction. The framework's flexible architecture allows integration of any molecular embedding technique with modern machine…

化学物理 · 物理学 2025-05-14 Aravindh Nivas Marimuthu , Brett A. McGuire

Spectroscopic properties of molecules holds great importance for the description of the molecular response under the effect of an UV/Vis electromagnetic radiation. Computationally expensive ab initio (e.g. MultiConfigurational SCF, Coupled…

Computer-driven molecular design combines the principles of chemistry, physics, and artificial intelligence to identify novel chemical compounds and materials with desired properties for a specific application. In particular,…

化学物理 · 物理学 2023-09-04 Alessio Fallani , Leonardo Medrano Sandonas , Alexandre Tkatchenko

Chemically accurate and comprehensive studies of the virtual space of all possible molecules are severely limited by the computational cost of quantum chemistry. We introduce a composite strategy that adds machine learning corrections to…

At the Institute for Thermodynamics and Thermal Process Engineering (ITT) about 100 molecular models for pure substances have been developed so far. These models reproduce vapor pressure, saturated liquid density, and enthalpy of…

计算物理 · 物理学 2009-04-22 Bernhard Eckl , Martin Horsch , Jadran Vrabec , Hans Hasse

Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determination of molecular properties under native solution…

Direct searches for sub-GeV dark matter are limited by the intrinsic quantum properties of the target material. In this proof-of-concept study, we argue that this problem is particularly well suited for machine learning. We demonstrate that…

高能物理 - 唯象学 · 物理学 2025-12-18 Cameron Cook , Carlos Blanco , Juri Smirnov

A new approach for describing the effective electronic states of "atoms in compounds" to study the properties of molecules and condensed matter which are circumscribed by the operators heavily concentrated in atomic cores is proposed. Among…

化学物理 · 物理学 2014-12-02 Anatoly V. Titov , Yuriy V. Lomachuk , Leonid V. Skripnikov

Rational design of interface passivators for perovskite solar cells is hindered by the entanglement of intrinsic molecular efficacy with extrinsic platform-dependent performance - a confounding factor that obscures true chemical advances.…

材料科学 · 物理学 2026-03-04 Jing Zhang , Ziyuan Li , Shan Gao , Zhen Zhu , Jing Wang , Xiangmei Duan

Exact calculation of electronic properties of molecules is a fundamental step for intelligent and rational compounds and materials design. The intrinsically graph-like and non-vectorial nature of molecular data generates a unique and…

化学物理 · 物理学 2019-10-29 Alain Tchagang , Julio Valdés

Coherent control, a central concept in physics and chemistry, has sparked significant interest due to its ability to fine-tune interference effects in atoms and individual molecules for applications ranging from light-harvesting complexes…

量子物理 · 物理学 2026-01-07 Juan M. Scarpetta , Omar Calderón-Losada , Morten Hjorth-Jensen , John H. Reina
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