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Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

计算与语言 · 计算机科学 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage…

计算与语言 · 计算机科学 2026-05-08 Xin Gao , Ruiyi Zhang , Meixi Du , Peijia Qin , Pengtao Xie

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

This paper presents a comprehensive evaluation of cost-efficient Large Language Models (LLMs) for diverse biomedical tasks spanning both text and image modalities. We evaluated a range of closed-source and open-source LLMs on tasks such as…

计算与语言 · 计算机科学 2025-07-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Biomedical text mining and question-answering are essential yet highly demanding tasks, particularly in the face of the exponential growth of biomedical literature. In this work, we present our participation in the 13th edition of the…

计算与语言 · 计算机科学 2025-08-05 Dimitra Panou , Alexandros C. Dimopoulos , Manolis Koubarakis , Martin Reczko

Developing therapeutics is a lengthy and expensive process that requires the satisfaction of many different criteria, and AI models capable of expediting the process would be invaluable. However, the majority of current AI approaches…

To enhance the performance of large language models (LLMs) in biomedical natural language processing (BioNLP) by introducing a domain-specific instruction dataset and examining its impact when combined with multi-task learning principles.…

计算与语言 · 计算机科学 2024-06-10 Hieu Tran , Zhichao Yang , Zonghai Yao , Hong Yu

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

数字图书馆 · 计算机科学 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

Natural medicines, particularly Traditional Chinese Medicine (TCM), are gaining global recognition for their therapeutic potential in addressing human symptoms and diseases. TCM, with its systematic theories and extensive practical…

计算与语言 · 计算机科学 2025-05-20 Zhi Liu , Tao Yang , Jing Wang , Yexin Chen , Zhan Gao , Jiaxi Yang , Kui Chen , Bingji Lu , Xiaochen Li , Changyong Luo , Yan Li , Xiaohong Gu , Peng Cao

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

计算与语言 · 计算机科学 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Large Language Models (LLMs) have the unique capability to understand and generate human-like text from input queries. When fine-tuned, these models show enhanced performance on domain-specific queries. OpenAI highlights the process of…

计算与语言 · 计算机科学 2024-07-02 Scott Barnett , Zac Brannelly , Stefanus Kurniawan , Sheng Wong

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

The rapid growth of biomedical literature poses challenges for manual knowledge curation and synthesis. Biomedical Natural Language Processing (BioNLP) automates the process. While Large Language Models (LLMs) have shown promise in general…

Large Language Models (LLMs), such as the LLaMA model, have demonstrated their effectiveness in various general-domain natural language processing (NLP) tasks. Nevertheless, LLMs have not yet performed optimally in biomedical domain tasks…

计算与语言 · 计算机科学 2023-04-17 Haochun Wang , Chi Liu , Nuwa Xi , Zewen Qiang , Sendong Zhao , Bing Qin , Ting Liu

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

计算与语言 · 计算机科学 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

This paper investigates the challenges of developing large language models (LLMs) proficient in both multilingual understanding and medical knowledge. We demonstrate that simply translating medical data does not guarantee strong performance…

计算与语言 · 计算机科学 2025-01-20 Nada Saadi , Tathagata Raha , Clément Christophe , Marco AF Pimentel , Ronnie Rajan , Praveen K Kanithi

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

计算与语言 · 计算机科学 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the…

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