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Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

Although Large Language Models (LLMs) demonstrate strong capabilities across various tasks, they exhibit significant performance discrepancies across languages. While prompting LLMs in English typically yields the highest general…

计算与语言 · 计算机科学 2026-05-26 Andrew Ivan Soegeng , Patrick Sutanto , Tan Sang Nguyen

Objective: Today's neural machine translation (NMT) can achieve near human-level translation quality and greatly facilitates international communications, but the lack of parallel corpora poses a key problem to the development of…

计算与语言 · 计算机科学 2022-02-08 Shengxuan Luo , Huaiyuan Ying , Jiao Li , Sheng Yu

Large Language Models (LLMs) are pretrained on extensive multilingual corpora to acquire both language-specific cultural knowledge and general knowledge. Ideally, while LLMs should provide consistent responses to culture-independent…

计算与语言 · 计算机科学 2025-02-11 Yumeng Wang , Zhiyuan Fan , Qingyun Wang , May Fung , Heng Ji

The combination of multilingual pre-trained representations and cross-lingual transfer learning is one of the most effective methods for building functional NLP systems for low-resource languages. However, for extremely low-resource…

计算与语言 · 计算机科学 2021-04-19 Mengzhou Xia , Guoqing Zheng , Subhabrata Mukherjee , Milad Shokouhi , Graham Neubig , Ahmed Hassan Awadallah

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

计算机视觉与模式识别 · 计算机科学 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Medical vision-language pretraining (VLP) models have recently been investigated for their generalization to diverse downstream tasks. However, current medical VLP methods typically force the model to learn simple and complex concepts…

计算机视觉与模式识别 · 计算机科学 2026-03-11 Chenran Zhang , Ruiqi Wu , Tao Zhou , Yi Zhou

Cross-lingual knowledge transfer is critical for building high-performing multilingual language models for languages with insufficient training data. When target language data is scarce, the knowledge required for many downstream tasks…

计算与语言 · 计算机科学 2026-05-25 Anastasiia Sedova , Natalie Schluter , Skyler Seto , Maartje ter Hoeve

We present BioLangFusion, a simple approach for integrating pre-trained DNA, mRNA, and protein language models into unified molecular representations. Motivated by the central dogma of molecular biology (information flow from gene to…

机器学习 · 计算机科学 2025-06-11 Amina Mollaysa , Artem Moskale , Pushpak Pati , Tommaso Mansi , Mangal Prakash , Rui Liao

This paper explores training medical vision-language models (VLMs) -- where the visual and language inputs are embedded into a common space -- with a particular focus on scenarios where training data is limited, as is often the case in…

计算机视觉与模式识别 · 计算机科学 2023-04-03 Rhydian Windsor , Amir Jamaludin , Timor Kadir , Andrew Zisserman

Large Language Models (LLMs) have achieved remarkable progress in recent years; however, their excellent performance is still largely limited to major world languages, primarily English. Many LLMs continue to face challenges with…

Several medical Multimodal Large Languange Models (MLLMs) have been developed to address tasks involving visual images with textual instructions across various medical modalities, achieving impressive results. Most current medical…

计算机视觉与模式识别 · 计算机科学 2025-04-08 Lehan Wang , Haonan Wang , Honglong Yang , Jiaji Mao , Zehong Yang , Jun Shen , Xiaomeng Li

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage…

计算与语言 · 计算机科学 2026-05-08 Xin Gao , Ruiyi Zhang , Meixi Du , Peijia Qin , Pengtao Xie

The scarcity of high-quality multimodal biomedical data limits the ability to effectively fine-tune pretrained Large Language Models (LLMs) for specialized biomedical tasks. To address this challenge, we introduce MINT (Multimodal…

定量方法 · 定量生物学 2026-02-18 Zhanliang Wang , Da Wu , Quan Nguyen , Zhuoran Xu , Kai Wang

Protein language models have shown remarkable success in learning biological information from protein sequences. However, most existing models are limited by either autoencoding or autoregressive pre-training objectives, which makes them…

English pretrained language models, which make up the backbone of many modern NLP systems, require huge amounts of unlabeled training data. These models are generally presented as being trained only on English text but have been found to…

计算与语言 · 计算机科学 2022-11-18 Terra Blevins , Luke Zettlemoyer

In Natural Language Processing (NLP), Machine Reading Comprehension (MRC) is the task of answering a question based on a given context. To handle questions in the medical domain, modern language models such as BioBERT, SciBERT and even…

计算与语言 · 计算机科学 2024-12-16 Saptarshi Sengupta , Connor Heaton , Suhan Cui , Soumalya Sarkar , Prasenjit Mitra

Large Language Models (LLMs) have introduced a new era of proficiency in comprehending complex healthcare and biomedical topics. However, there is a noticeable lack of models in languages other than English and models that can interpret…

计算机视觉与模式识别 · 计算机科学 2023-11-02 Junling Liu , Ziming Wang , Qichen Ye , Dading Chong , Peilin Zhou , Yining Hua

Human expertise in chemistry and biomedicine relies on contextual molecular understanding, a capability that large language models (LLMs) can extend through fine-grained alignment between molecular structures and text. Recent multimodal…

计算与语言 · 计算机科学 2025-03-10 Sumin Ha , Jun Hyeong Kim , Yinhua Piao , Sun Kim

Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited…

计算与语言 · 计算机科学 2025-01-14 Haochun Wang , Sendong Zhao , Zewen Qiang , Zijian Li , Nuwa Xi , Yanrui Du , MuZhen Cai , Haoqiang Guo , Yuhan Chen , Haoming Xu , Bing Qin , Ting Liu