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Colorectal cancer frequently metastasizes to the liver, significantly reducing long-term survival. While surgical resection is the only potentially curative treatment for colorectal liver metastasis (CRLM), patient outcomes vary widely…

计算机视觉与模式识别 · 计算机科学 2025-09-12 Muhammad Alberb , Helen Cheung , Anne Martel

Colorectal cancer liver metastases (CLM) are the most common type of distant metastases originating from the abdomen and are characterized by a high recurrence rate after curative resection. It has been previously reported that CLM…

定量方法 · 定量生物学 2023-03-09 Ralph Saber , David Henault , Rolando Rebolledo , Simon Turcotte , Samuel Kadoury

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

图像与视频处理 · 电气工程与系统科学 2023-03-21 Yinsheng He , Xingyu Li

While colorectal liver metastasis (CRLM) is potentially curable via hepatectomy, patient outcomes remain highly heterogeneous. Postoperative survival prediction is necessary to avoid non-beneficial surgeries and guide personalized therapy.…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Muhammad Alberb , Jianan Chen , Hossam El-rewaidy , Paul Karanicolas , Arun Seth , Yutaka Amemiya , Anne Martel , Helen Cheung

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

图像与视频处理 · 电气工程与系统科学 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Prognostic evaluation in patients with colorectal liver metastases (CRLM) remains challenging due to suboptimal accuracy of conventional clinical models. This study developed and validated a robust machine learning model for predicting…

图像与视频处理 · 电气工程与系统科学 2025-07-29 Qinlong Li , Pu Sun , Guanlin Zhu , Tianjiao Liang , Honggang QI

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

计算机视觉与模式识别 · 计算机科学 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Faisal Ahmed

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

计算机视觉与模式识别 · 计算机科学 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler

Vision transformers (ViT) have been shown to allow for more flexible feature detection and can outperform convolutional neural network (CNN) when pre-trained on sufficient data. Due to their promising feature detection capabilities, we…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Nghia , Nguyen , Amer Wahed , Andy Quesada , Yasir Ali , Hanadi El Achi , Y. Helen Zhang , Jocelyn Ursua , Alex Banerjee , Sahib Kalra , L. Jeffrey Medeiros , Jie Xu

Recent advances in machine learning are transforming medical image analysis, particularly in cancer detection and classification. Techniques such as deep learning, especially convolutional neural networks (CNNs) and vision transformers…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Arezoo Borji , Gernot Kronreif , Bernhard Angermayr , Sepideh Hatamikia

Deep learning has proven very promising for interpreting MRI in brain tumor diagnosis. However, deep learning models suffer from a scarcity of brain MRI datasets for effective training. Self-supervised learning (SSL) models provide…

图像与视频处理 · 电气工程与系统科学 2024-11-21 Meryem Altin Karagoz , O. Ufuk Nalbantoglu , Geoffrey C. Fox

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Juexin Zhang , Qifeng Zhong , Ying Weng , Ke Chen

In routine colorectal cancer management, histologic samples stained with hematoxylin and eosin are commonly used. Nonetheless, their potential for defining objective biomarkers for patient stratification and treatment selection is still…

定量方法 · 定量生物学 2024-09-26 Fabi Prezja , Leevi Annala , Sampsa Kiiskinen , Suvi Lahtinen , Timo Ojala , Pekka Ruusuvuori , Teijo Kuopio

Purpose Tumor-infiltrating lymphocytes (TILs) have significant prognostic values in cancers. However, very few automated, deep-learning-based TIL scoring algorithms have been developed for colorectal cancers (CRC). Methods We developed an…

定量方法 · 定量生物学 2022-09-16 Anran Liu , Xingyu Li , Hongyi Wu , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

In recent days, Deep Learning (DL) techniques have become an emerging transformation in the field of machine learning, artificial intelligence, computer vision, and so on. Subsequently, researchers and industries have been highly endorsed…

图像与视频处理 · 电气工程与系统科学 2023-11-21 P. Kalaiselvi , S. Anusuya
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