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Image based biomarker discovery typically requires an accurate segmentation of histologic structures (e.g., cell nuclei, tubules, epithelial regions) in digital pathology Whole Slide Images (WSI). Unfortunately, annotating each structure of…

图像与视频处理 · 电气工程与系统科学 2021-01-07 Runtian Miao , Robert Toth , Yu Zhou , Anant Madabhushi , Andrew Janowczyk

In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via…

计算机视觉与模式识别 · 计算机科学 2025-08-15 Myeongjang Pyeon , Janghyeon Lee , Minsoo Lee , Juseung Yun , Hwanil Choi , Jonghyun Kim , Jiwon Kim , Yi Hu , Jongseong Jang , Soonyoung Lee

Automatic pain intensity estimation plays a pivotal role in healthcare and medical fields. While many methods have been developed to gauge human pain using behavioral or physiological indicators, facial expressions have emerged as a…

计算机视觉与模式识别 · 计算机科学 2023-12-13 Issam Serraoui , Eric Granger , Abdenour Hadid , Abdelmalik Taleb-Ahmed

Deciphering tumor microenvironment from Whole Slide Images (WSIs) is intriguing as it is key to cancer diagnosis, prognosis and treatment response. While these gigapixel images on one hand offer a comprehensive portrait of cancer, on the…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Kunpeng Zhang , Hanwen Xu , Sheng Wang

In recent years, deep learning has successfully been applied to automate a wide variety of tasks in diagnostic histopathology. However, fast and reliable localization of small-scale regions-of-interest (ROI) has remained a key challenge, as…

图像与视频处理 · 电气工程与系统科学 2022-01-06 Jon Braatz , Pranav Rajpurkar , Stephanie Zhang , Andrew Y. Ng , Jeanne Shen

Cancer diseases constitute one of the most significant societal challenges. In this paper, we introduce a novel histopathological dataset for prostate cancer detection. The proposed dataset, consisting of over 2.6 million tissue patches…

Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular…

图像与视频处理 · 电气工程与系统科学 2025-03-25 Yang Luo , Shiru Wang , Jun Liu , Jiaxuan Xiao , Rundong Xue , Zeyu Zhang , Hao Zhang , Yu Lu , Yang Zhao , Yutong Xie

Abundant accumulation of digital histopathological images has led to the increased demand for their analysis, such as computer-aided diagnosis using machine learning techniques. However, digital pathological images and related tasks have…

计算机视觉与模式识别 · 计算机科学 2018-02-23 Daisuke Komura , Shumpei Ishikawa

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

图像与视频处理 · 电气工程与系统科学 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Few-shot learning presents a critical solution for cancer diagnosis in computational pathology (CPath), addressing fundamental limitations in data availability, particularly the scarcity of expert annotations and patient privacy…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Zhengrui Guo , Conghao Xiong , Jiabo Ma , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

We explore three representative lines of research and demonstrate the utility of our methods on a classification benchmark of brain cancer MRI data. First, we present a capsule network that explicitly learns a representation robust to…

图像与视频处理 · 电气工程与系统科学 2020-05-13 Neil Getty , Thomas Brettin , Dong Jin , Rick Stevens , Fangfang Xia

We present an effective application of quantum machine learning in the field of healthcare. The study here emphasizes on a classification problem of a histopathological cancer detection using quantum transfer learning. Rather than using…

量子物理 · 物理学 2023-02-10 Reek Majumdar , Biswaraj Baral , Bhavika Bhalgamiya , Taposh Dutta Roy

Background: Histopathology is an important modality for the diagnosis and management of many diseases in modern healthcare, and plays a critical role in cancer care. Pathology samples can be large and require multi-site sampling, leading to…

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

计算机视觉与模式识别 · 计算机科学 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

计算机视觉与模式识别 · 计算机科学 2025-10-07 Nabil Daiyan , Md Rakibul Haque

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Weakly-supervised classification of histopathology slides is a computationally intensive task, with a typical whole slide image (WSI) containing billions of pixels to process. We propose Discriminative Region Active Sampling for Multiple…

图像与视频处理 · 电气工程与系统科学 2023-02-23 Jack Breen , Katie Allen , Kieran Zucker , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of…