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Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…

计算机视觉与模式识别 · 计算机科学 2019-02-21 Shujun Wang , Lequan Yu , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

Glaucoma, a leading cause of blindness, is characterized by optic nerve damage related to intraocular pressure (IOP), but its full etiology is unknown. Researchers at UAB have devised a custom device to measure scleral strain continuously…

Diabetic retinopathy (DR) is one of the leading causes of vision loss worldwide, making early and accurate DR grading critical for timely intervention. Recent clinical practices leverage multi-view fundus images for DR detection with a wide…

计算机视觉与模式识别 · 计算机科学 2026-02-26 Haoran Li , Yuxin Lin , Huan Wang , Xiaoling Luo , Qi Zhu , Jiahua Shi , Huaming Chen , Bo Du , Johan Barthelemy , Zongyan Xue , Jun Shen , Yong Xu

Objective: Ophthalmological pathologies such as glaucoma, diabetic retinopathy and age-related macular degeneration are major causes of blindness and vision impairment. There is a need for novel decision support tools that can simplify and…

图像与视频处理 · 电气工程与系统科学 2023-06-08 Or Abramovich , Hadas Pizem , Jan Van Eijgen , Ilan Oren , Joshua Melamed , Ingeborg Stalmans , Eytan Z. Blumenthal , Joachim A. Behar

Recently, deep learning has been adopted to the glaucoma classification task with performance comparable to that of human experts. However, a well trained deep learning model demands a large quantity of properly labeled data, which is…

计算机视觉与模式识别 · 计算机科学 2020-07-23 Junde Wu , Shuang Yu , Wenting Chen , Kai Ma , Rao Fu , Hanruo Liu , Xiaoguang Di , Yefeng Zheng

Here, we examine the latest advances in glaucoma detection through Deep Learning (DL) algorithms using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study focuses on three aspects of DL-based glaucoma…

图像与视频处理 · 电气工程与系统科学 2024-11-12 Mahtab Faraji , Homa Rashidisabet , George R. Nahass , RV Paul Chan , Thasarat S Vajaranant , Darvin Yi

Background and Objective: To address the inability of single-model architectures to perform simultaneous analysis of complex glomerular ultrastructures, we developed Glo-UMF, a unified multi-model framework integrating segmentation,…

计算机视觉与模式识别 · 计算机科学 2025-09-12 Zhentai Zhang , Danyi Weng , Guibin Zhang , Xiang Chen , Kaixing Long , Jian Geng , Yanmeng Lu , Lei Zhang , Zhitao Zhou , Lei Cao

Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions. Participants: A…

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

图像与视频处理 · 电气工程与系统科学 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

Ultra-Wide-Field Fluorescein Angiography (UWF-FA) enables precise identification of ocular diseases using sodium fluorescein, which can be potentially harmful. Existing research has developed methods to generate UWF-FA from Ultra-Wide-Field…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Zhaojie Fang , Xiao Yu , Guanyu Zhou , Ke Zhuang , Yifei Chen , Ruiquan Ge , Changmiao Wang , Gangyong Jia , Qing Wu , Juan Ye , Maimaiti Nuliqiman , Peifang Xu , Ahmed Elazab

Hyperspectral image (HSI) classification has recently reached its performance bottleneck. Multimodal data fusion is emerging as a promising approach to overcome this bottleneck by providing rich complementary information from the…

计算机视觉与模式识别 · 计算机科学 2024-06-26 Xuming Zhang , Naoto Yokoya , Xingfa Gu , Qingjiu Tian , Lorenzo Bruzzone

Fundus photography is prone to suffer from image quality degradation that impacts clinical examination performed by ophthalmologists or intelligent systems. Though enhancement algorithms have been developed to promote fundus observation on…

图像与视频处理 · 电气工程与系统科学 2023-09-12 Heng Li , Haofeng Liu , Huazhu Fu , Yanwu Xu , Hui Shu , Ke Niu , Yan Hu , Jiang Liu

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Cancer is one of the leading causes of death worldwide, making the development of rapid, minimally invasive, label-free and scalable diagnostic strategies a major challenge in modern oncology. In this context, spectroscopic liquid biopsy…

This paper studies automated categorization of age-related macular degeneration (AMD) given a multi-modal input, which consists of a color fundus image and an optical coherence tomography (OCT) image from a specific eye. Previous work uses…

图像与视频处理 · 电气工程与系统科学 2019-07-30 Weisen Wang , Zhiyan Xu , Weihong Yu , Jianchun Zhao , Jingyuan Yang , Feng He , Zhikun Yang , Di Chen , Dayong Ding , Youxin Chen , Xirong Li

Multi-modal ophthalmic image classification plays a key role in diagnosing eye diseases, as it integrates information from different sources to complement their respective performances. However, recent improvements have mainly focused on…

图像与视频处理 · 电气工程与系统科学 2024-05-29 Ke Zou , Tian Lin , Zongbo Han , Meng Wang , Xuedong Yuan , Haoyu Chen , Changqing Zhang , Xiaojing Shen , Huazhu Fu

Skin cancer is a highly dangerous type of cancer that requires an accurate diagnosis from experienced physicians. To help physicians diagnose skin cancer more efficiently, a computer-aided diagnosis (CAD) system can be very helpful. In this…

图像与视频处理 · 电气工程与系统科学 2024-06-24 Ayush Roy , Sujan Sarkar , Sohom Ghosal , Dmitrii Kaplun , Asya Lyanova , Ram Sarkar

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

医学物理 · 物理学 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Large language models (LLMs) can simulate clinical reasoning based on natural language prompts, but their utility in ophthalmology is largely unexplored. This study evaluated GPT-4's ability to interpret structured textual descriptions of…

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